Description

Procyclidine Hydrochloride Tablets (5 mg)

Healthy Inc is a specialized global supplier and exporter of advanced neurology, psychiatric, and central nervous system (CNS) therapeutics. We provide ultra-high-purity, kinetically precise Procyclidine Hydrochloride Tablets (5 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Central Anticholinergic Agent” is a highly lucrative, massive-volume export to psychiatric hospitals, neurology centers, retail pharmacy networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, rapid-response intervention for drug-induced Extrapyramidal Symptoms (EPS) and idiopathic Parkinsonism.

Product Overview

This highly targeted formulation contains Procyclidine, a synthetic tertiary amine that acts as a powerful central nervous system shield, restoring the delicate neurochemical balance required for smooth, voluntary muscle movement.

The “EPS Antidote & Neuro-Balancer” Specialist:

• Mechanism 1 (The Acetylcholine-Dopamine Seesaw): In a healthy brain, dopamine and acetylcholine exist in perfect balance to control movement. In Parkinson’s Disease—or when a patient is taking heavy antipsychotic drugs that block dopamine—this balance is destroyed. Acetylcholine becomes completely dominant, causing severe tremors, extreme muscle rigidity, and uncontrollable restlessness (akathisia). Procyclidine acts as a central anticholinergic. It crosses the blood-brain barrier and aggressively blocks the muscarinic acetylcholine receptors, forcing the “seesaw” back into balance and rapidly halting the tremors.
• Mechanism 2 (The Psychiatric Ward Essential): Up to 70% of patients on first-generation antipsychotics (and many on second-generation drugs) develop agonizing, drug-induced parkinsonism. Procyclidine is the high-volume, mandatory co-prescription in these wards. It rapidly reverses acute dystonic reactions (severe, painful muscle spasms of the neck, jaw, and eyes), ensuring patient compliance with life-saving psychiatric therapies.
• Sialorrhea (Drooling) Control: A secondary, highly beneficial effect of its anticholinergic properties is the severe drying of salivary secretions. This provides immense clinical relief for Parkinson’s and psychiatric patients suffering from severe, socially debilitating drooling (sialorrhea).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Psychiatric Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Precision Low-Dose Blending: Manufacturing a 5 mg central nervous system drug requires strict geometric dilution and advanced high-shear wet granulation. Our facilities utilize rigorous HPLC content uniformity protocols to guarantee that every single tablet delivers the exact milligram dose, completely eliminating the risk of anticholinergic toxicity (over-dosing) or treatment failure (under-dosing) in highly vulnerable psychiatric patients.

Therapeutic Indications (Human Use)

Indicated for the targeted management of severe extrapyramidal and parkinsonian motor dysfunction:

• Drug-Induced Extrapyramidal Symptoms (EPS): Treatment of pseudo-parkinsonism, acute dystonia, and akathisia induced by neuroleptic drugs (phenothiazines, butyrophenones) or reserpine.
• Parkinson’s Disease: Adjunctive treatment of all forms of Parkinson’s syndrome (idiopathic, post-encephalitic, and arteriosclerotic), specifically targeting rigidity, tremors, and excessive salivation.

Dosage & Administration

Recommended Dosage (Strictly as per Psychiatrist/Neurologist Guidelines):

• Drug-Induced EPS: Generally initiated at 2.5 mg three times a day. If well-tolerated and symptoms persist, the dose may be increased to 5 mg three times a day (TID).
• Parkinson’s Disease: Usually initiated at 2.5 mg three times daily, gradually increasing up to 20-30 mg daily in divided doses based on clinical response.
• Administration (THE MEALTIME RULE): To minimize the risk of severe gastric irritation and nausea, the tablets should be taken after meals.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Narrow-Angle Glaucoma (Absolute Contraindication): Procyclidine causes the pupils to dilate (mydriasis). In patients with narrow-angle glaucoma, this will physically block the drainage of fluid from the eye, causing a massive, agonizing spike in intraocular pressure that can lead to rapid, irreversible blindness.
• The Anticholinergic Toxidrome: High doses cause severe systemic drying and neurological side effects. Patients must be monitored for the classic symptoms: “Red as a beet, dry as a bone, blind as a bat, mad as a hatter, hot as a hare” (severe dry mouth, blurred vision, urinary retention, severe constipation, and acute confusion/delirium).
• Elderly Patient Susceptibility: Geriatric patients are exquisitely sensitive to central anticholinergics. Standard doses can precipitate sudden, severe cognitive impairment, hallucinations, and urinary retention (especially in men with enlarged prostates). Extreme caution and severe dose reductions are required.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and NGO Health Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Neurological and Psychiatric Formulations. Whether you are looking for a reliable Government Tender Supplier for asylum networks in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.