Description

Metronidazole Capsules

Healthy Inc is a specialized global supplier and exporter of essential antimicrobial, antiprotozoal, and gastrointestinal therapeutics. We provide high-purity Metronidazole Capsules (500 mg), manufactured in WHO–GMP certified oral solid dosage facilities. This “Nitroimidazole Antimicrobial” is a massive-volume, absolute-priority export to infectious disease hospitals, NGO epidemic response teams, primary care clinics, and government health ministries in Africa, LATAM, the Middle East, and Southeast Asia, serving as the globally trusted, first-line intervention for severe amebic dysentery, trichomoniasis, and deep-tissue anaerobic infections.

Product Overview

This formulation contains Metronidazole, a synthetic nitroimidazole derivative with highly potent, rapid bactericidal and antiprotozoal activity.

The “Anaerobic DNA Destroyer” Specialist:

• Mechanism (Intracellular Reduction & DNA Breakage): Metronidazole is essentially a prodrug that is only activated in oxygen-starved (anaerobic) environments. Once it enters the anaerobic bacterium or protozoan, microbial proteins (like ferredoxin) reduce the drug’s nitro group. This creates highly reactive, short-lived cytotoxic free radicals that violently attack the microbe’s DNA, causing devastating strand breakages, halting nucleic acid synthesis, and ensuring immediate cell death.
• The Capsule Compliance Advantage: Metronidazole API is notoriously bitter and leaves a lingering, nauseating metallic taste in the mouth when taken as a standard compressed tablet. Our hard gelatin capsule formulation completely seals the API, entirely bypassing the taste buds. This drastically improves patient adherence—a critical metric for NGOs and infectious disease specialists managing 7-to-10-day eradication protocols.
• Broad-Spectrum GI & STI Utility: It is the undisputed global gold standard for treating severe protozoal diarrhea (Amebiasis and Giardiasis), the most common curable Sexually Transmitted Infection (Trichomoniasis), and is a vital component in treating Bacterial Vaginosis (BV) and pelvic inflammatory disease.

Product Composition & Strength

We supply this product as a Hard Gelatin Capsule, packed in highly secure, moisture-resistant Alu-PVC or Alu-Alu blister strips to ensure API stability in extreme tropical climates.

*Pack Sizes: 10×10 Alu-PVC Blisters (optimized for standard 7-to-10 day infectious disease dispensing cycles).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and NGO Outbreak Response Teams.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• API Purity & Bioavailability: Metronidazole must be rapidly absorbed in the GI tract to achieve the high peak serum concentrations required for systemic and deep-tissue infections. Our encapsulation process utilizes premium superdisintegrants to ensure the capsule ruptures immediately in the stomach, providing systemic bioavailability approaching 100%.
• Cross-Contamination Protocols: Manufactured in strictly controlled, segregated zones to prevent any cross-contamination with beta-lactam antibiotics, ensuring total safety for penicillin-allergic patients.

Therapeutic Indications (Human Use)

Indicated for the comprehensive treatment of severe anaerobic bacterial and protozoal infections:

• Amebiasis & Giardiasis: Treatment of acute intestinal amebiasis (amebic dysentery), amebic liver abscesses, and giardiasis.
• Trichomoniasis & Bacterial Vaginosis: Eradication of Trichomonas vaginalis (requires concurrent treatment of sexual partners) and symptomatic Bacterial Vaginosis.
• Anaerobic Bacterial Infections: Treatment of severe intra-abdominal infections, skin/skin structure infections, gynecologic infections, and bacterial septicemia caused by Bacteroides fragilis, Clostridium species, and Peptostreptococcus.
• Helicobacter pylori Eradication: Used off-label in combination with other antibiotics and a PPI (like Omeprazole) for patients allergic to penicillin.

Dosage & Administration

Recommended Dosage (Strictly as per Infectious Disease Specialist):

• Administration: Should be taken orally. Taking the capsule with food or a full glass of water or milk drastically reduces the mild gastrointestinal irritation frequently caused by the drug.
• Swallowing Protocol: Must be swallowed whole to preserve the taste-masking benefit of the capsule.
• Treatment Duration (CRITICAL): Patients must complete the entire prescribed course (usually 7 to 10 days) even if symptoms disappear after a few days, to prevent the survival of resistant protozoal cysts or anaerobic spores.

Safety Warnings (CRITICAL):

• The Disulfiram-Like Reaction (SEVERE ALCOHOL WARNING): Metronidazole blocks the metabolism of alcohol, causing a violent, toxic buildup of acetaldehyde. Patients MUST NOT consume any alcohol (or propylene glycol-containing products) during therapy and for at least 48 to 72 hours after the final dose. Doing so will cause severe abdominal cramps, violent vomiting, flushing, and intense headaches.
• Neurological Toxicity: High doses or prolonged use can cause severe central and peripheral nervous system toxicity, presenting as peripheral neuropathy (numbness/tingling in hands and feet), encephalopathy, or convulsive seizures. Treatment must be stopped immediately if neurological symptoms arise.
• Carcinogenicity (BLACK BOX EQUIVALENT): Metronidazole has been shown to be carcinogenic in mice and rats. It should be used strictly for approved indications and unnecessary, prolonged use must be avoided.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Essential Antimicrobial Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable NGO Tender Supplier for dysentery outbreak procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.