Description

Dexamethasone Tablets

Healthy Inc is a specialized global supplier and exporter of high-potency synthetic corticosteroids. We provide high-purity Dexamethasone Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Anti-Inflammatory Powerhouse” is a top export to critical care units, oncology centers, and government health ministries in Africa, LATAM, and Southeast Asia, serving as a frontline therapy for severe allergies, cerebral edema, and acute respiratory distress protocols (including COVID-19 management).

Product Overview

This formulation contains Dexamethasone, a long-acting fluorinated glucocorticoid.

The “Potency” Specialist:

• Mechanism (Genomic Action): Dexamethasone diffuses into cells and binds to specific Glucocorticoid Receptors (GR) in the cytoplasm. This complex enters the nucleus and modulates DNA transcription, inhibiting the synthesis of pro-inflammatory cytokines (IL-1, IL-6, TNF-alpha) and prostaglandins.
• High Potency: It is approximately 25 to 30 times more potent than Hydrocortisone and 5 to 7 times more potent than Prednisolone.
• Zero Mineralocorticoid Effect: Unlike other steroids, Dexamethasone has virtually no salt-retaining properties (no sodium retention). This makes it the drug of choice for treating cerebral edema and for patients with heart failure or hypertension where fluid retention must be avoided.
• Long Duration: It has a biological half-life of 36 to 54 hours, providing sustained suppression of inflammation.

Product Composition & Strength

We supply this product as Uncoated Tablets (typically White, Round, Scored). The scoring allows for precise dose tapering.

*Pack Sizes: Blister packs of 10s (Box of 10×10), 20s, 30s, or Bulk HDPE Jars of 1000s/5000s (Hospital Packs).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Content Uniformity: The 0.5 mg dose contains a very small amount of active drug. We use Geometric Dilution and high-precision blending technology to ensure that every tablet contains exactly 0.5 mg, preventing sub-therapeutic dosing or toxicity.
• Micronization: The API is micronized to < 10 microns to ensure rapid dissolution and immediate bioavailability, critical for acute allergic reactions.

Therapeutic Indications (Human Use)

Indicated for the management of severe inflammatory and autoimmune conditions:

• Cerebral Edema: Associated with primary or metastatic brain tumors, craniotomy, or head injury.
• Respiratory Disorders: Severe bronchial asthma, aspiration pneumonitis, and **COVID-19** (in patients requiring oxygen support).
• Autoimmune Diseases: Rheumatoid arthritis, Systemic Lupus Erythematosus (SLE), and Pemphigus.
• Oncology: Used as an antiemetic (to prevent nausea from chemotherapy) and as a direct treatment for Multiple Myeloma/Leukemia.
• Diagnostic: Dexamethasone Suppression Test (DST) for diagnosing Cushing’s Syndrome.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Oral.
• Adults: Ranges widely from 0.75 mg to 9 mg daily depending on the disease severity.
• Cerebral Edema: Initially high dose (e.g., 16 mg), tapering down to 4 mg every 6 hours.
• COVID-19 (Hypoxic Patients): 6 mg once daily for up to 10 days.
• Administration: Take with food to minimize gastric irritation.

Safety Warnings:

• HPA Axis Suppression (WARNING): Long-term use suppresses the body’s natural cortisol production. DO NOT STOP ABRUPTLY. Taper slowly to prevent adrenal crisis (shock/death).
• Hyperglycemia: Significantly raises blood sugar. Diabetic patients require strict monitoring and insulin adjustment.
• Immunosuppression: Masks signs of infection and increases susceptibility to fungal/viral infections.
• Psychiatric Effects: Can cause insomnia, euphoria (“steroid high”), or severe depression/psychosis.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.