Description

Dexamethasone Sodium Phosphate Injection

Healthy Inc is a specialized global supplier and exporter of high-potency glucocorticoids. We provide high-purity Dexamethasone Sodium Phosphate Injection (4 mg / 8 mg / 20 mg), sourced from WHO–GMP certified sterile injectable facilities. This “Inflammation Firefighter” is a top export to intensive care units (ICU), respiratory wards, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the critical standard of care for severe allergies, cerebral edema, fetal lung maturation, and COVID-19 management.

Product Overview

This formulation contains Dexamethasone Sodium Phosphate, a synthetic adrenocortical steroid that is approximately 25-30 times more potent than hydrocortisone.

The “Systemic Shield” Specialist:

• Mechanism (Gene Regulation): Dexamethasone enters cells and binds to glucocorticoid receptors. This complex enters the nucleus and regulates gene expression, suppressing the production of inflammatory cytokines (like IL-6) and inhibiting the migration of white blood cells to sites of injury. This rapidly extinguishes the “cytokine storm” seen in severe infections and autoimmune reactions.
• Fetal Lung Maturation: It is the global standard for pregnant women at risk of preterm birth. Injection aids the production of surfactant in the fetus’s lungs, preventing Respiratory Distress Syndrome (RDS) in the newborn.
• Cerebral Edema: It is the most effective drug for reducing brain swelling caused by tumors or trauma.

Product Composition & Strength

We supply this product as a Sterile Solution in Glass Ampoules or Vials.

*Pack Sizes: Tray of 10 Ampoules, 50 Ampoules, or 100 Ampoules.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Oxidation Resistance: Corticosteroids are sensitive to oxidative degradation. We utilize Nitrogen Sparging during the filling process to remove dissolved oxygen, ensuring the solution remains potent and does not discolor over time.
• Preservative Optimization: For multi-dose vials, we use precise concentrations of Methylparaben/Propylparaben or Benzyl Alcohol to ensure sterility after the first puncture without causing hypersensitivity.

Therapeutic Indications (Human Use)

Indicated for conditions requiring potent anti-inflammatory or immunosuppressive action:

• Severe Allergic Reactions: Anaphylaxis, Status Asthmaticus, Angioedema.
• Cerebral Edema: Associated with primary or metastatic brain tumors.
• Preterm Labor: Induction of fetal lung maturation (prevention of RDS).
• COVID-19 (Severe): Reduces mortality in hospitalized patients requiring oxygen or ventilation (RECOVERY Trial Protocol).
• Shock: Adjunct in septic or anaphylactic shock.
• Autoimmune Disorders: Lupus (SLE), Rheumatoid Arthritis flares.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intravenous (IV) or Intramuscular (IM) Injection.
• Standard Adult Dose: 4 mg to 20 mg daily (divided doses).
• Cerebral Edema: Loading dose of 10 mg IV, followed by 4 mg IM every 6 hours.
• Fetal Lung Maturation: 6 mg IM every 12 hours for 4 doses.
• COVID-19: 6 mg IV/Oral once daily for up to 10 days.
• Shock: High dose (massive) pulses may be used (e.g., 20-40 mg).

Safety Warnings (CRITICAL):

• Hyperglycemia (Diabetes): Dexamethasone significantly raises blood sugar levels. Diabetics must monitor glucose closely. Insulin doses may need adjustment.
• Immune Suppression: Masks signs of infection. Do not use in active untreated fungal or tubercular infections.
• Adrenal Suppression: Sudden discontinuation after long-term use can cause fatal adrenal crisis. Taper dose gradually.
• Peptic Ulcer: Increases risk of GI bleeding.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.