Clotrimazole Vaginal Cream

Description

Clotrimazole Vaginal Cream (2.0% / 10.0% w/w)

Healthy Inc is a specialized global supplier and exporter of advanced gynaecology, anti-infectives, and targeted mucosal therapeutics. We provide ultra-high-purity, kinetically optimized Clotrimazole Vaginal Cream, manufactured in WHO–GMP certified, high-precision specialized topical and semi-solid facilities. This “Imidazole Antifungal” is a massive-volume strategic export to pharmacy chains, maternity hospitals, and government health tenders, serving as the globally mandated first-line intervention for Vulvovaginal Candidiasis (Yeast Infection).

Product Overview

This formulation operates as a “Cell Membrane Disruptor.” It is specifically engineered to adhere to the vaginal mucosa, ensuring the active ingredient remains in contact with the fungal colony long enough to ensure total eradication.

• Mechanism 1 (Ergosterol Synthesis Inhibition): Clotrimazole physically inhibits the enzyme lanosterol 14α-demethylase. This blocks the conversion of lanosterol to ergosterol, the essential component of the fungal cell wall.

• Mechanism 2 (Structural Lysis): The depletion of ergosterol physically leads to the formation of “pores” in the fungal membrane. This causes essential internal cellular components to leak out, leading to rapid cell death.

• Mechanism 3 (Muco-Adhesive Delivery): Our specialized cream base physically binds to the vaginal lining, preventing the “leak-out” often associated with lower-quality generics, and providing sustained therapeutic levels for 1 to 7 days.

Product Composition & Strength

We supply this product in a Smooth, Non-Greasy, Water-Washable Emulsion, optimized for delicate mucosal environments.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics – Antifungals)

• CAS Number: 23593-75-1 (Clotrimazole)

• Dosage Form: Vaginal Cream (O/W Emulsion)

• Packaging: Laminated Aluminum Tubes (30g or 35g for 2% / 5g for 10%) accompanied by Sterile Plastic Graduated Applicators. Our high-barrier packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Sterile Filling Standards: Our manufacturing process utilizes Class 100 (ISO 5) filling environments for the cream and applicators, ensuring the product is free from contaminants and safe for sensitive internal use.

• pH Standardization: We utilize Automated Buffering Systems to ensure the cream’s pH is precisely adjusted to the vaginal range (4.0–4.5). This physically prevents irritation and supports the growth of healthy Lactobacilli.

Primary Indications

• Gynaecology: Treatment of Vulvovaginal Candidiasis (Yeast Infections).

• Infectious Disease: Management of vaginal discharge and itching associated with Candida species.

• General Practice: Relief for secondary fungal irritation of the vulva.

Dosage & Administration

• 2% Cream (3-Day/6-Day): One full applicator (approx. 5g) inserted deep into the vagina once daily at bedtime for 3 or 6 consecutive days.

• 10% Cream (Single Dose): One full applicator (5g) inserted deep into the vagina as a single, one-time treatment.

• Note: Best used at night to maximize retention and absorption.

Safety Warning: Vaginal Use Only. Not for oral consumption. Latex Warning: The cream may physically weaken latex condoms and diaphragms; avoid sexual intercourse during treatment and for 3 days after. Contraindication: Do not use if known hypersensitivity to imidazole antifungals exists.

Global Export & Contract Manufacturing

Healthy Inc is a premier Gynaecology and Antifungal Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume vaginal topicals and suppository alternatives. Whether you are a National Health Tender in Africa or a B2B Pharma Marketplace partner in the CIS or LATAM, we ensure secure, WHO-GMP compliant delivery.

Commercial Inquiries:

WhatsApp/Call: +91 7710003340

Email: info@healthyinc.co.in