Description

Chloroquine Phosphate Tablets

Healthy Inc is a specialized global supplier and exporter of established antimalarial and anti-rheumatic agents. We provide high-purity Chloroquine Phosphate Tablets, sourced from WHO–GMP certified solid dosage facilities. This “First-Generation” 4-Aminoquinoline is a top export to National Malaria Control Programs, rheumatology clinics, and government dispensaries in Africa, LATAM, and Southeast Asia, serving as the drug of choice for non-falciparum malaria and sensitive strains of P. falciparum.

Product Overview

This formulation contains Chloroquine Phosphate, a synthetic 4-aminoquinoline derivative with rapid schizonticidal and anti-inflammatory activity.

The “Heme Poisoning” Specialist:

• Mechanism (Malaria): The malaria parasite digests hemoglobin inside its food vacuole, releasing toxic free heme. The parasite normally converts this toxic heme into non-toxic “hemozoin” crystals. Chloroquine concentrates in the vacuole and inhibits the enzyme heme polymerase. This blocks the detoxification process, causing toxic heme to build up and kill the parasite.
• Anti-Inflammatory (RA/Lupus): In autoimmune diseases, Chloroquine inhibits the migration of neutrophils and eosinophils and suppresses antigen presentation, effectively calming the overactive immune system in Rheumatoid Arthritis and Lupus.
• Amoebicidal Action: It concentrates highly in the liver (hundreds of times plasma levels), making it effective against Amoebic Liver Abscess where Metronidazole has failed or is contraindicated.

Product Composition & Strength

We supply this product as Film Coated Tablets or Uncoated Tablets. The strength is often labeled by the salt weight or the base equivalent.

*Pack Sizes: Blister packs of 10s (Box of 10×10), 500s, or Bulk HDPE Jars of 1000s (Hospital/Program Packs).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Taste Masking Engineering: Chloroquine is exceptionally bitter. An uncoated tablet can cause immediate vomiting in children, leading to treatment failure. We recommend our Film Coated variant, which utilizes a tasteless polymer barrier to ensure the dose is swallowed successfully.
• Dissolution: Rapid disintegration is engineered to ensure the drug reaches therapeutic blood levels quickly, essential for treating acute malarial fever.

Therapeutic Indications (Human Use)

Indicated for infectious and autoimmune conditions:

• Malaria Treatment: Cure of malaria caused by Plasmodium vivax, P. ovale, P. malariae, and sensitive strains of P. falciparum.
• Malaria Prophylaxis: Prevention of malaria in travelers to areas where Chloroquine resistance is not present (e.g., Central America/Caribbean).
• Amoebic Liver Abscess: Treatment of extra-intestinal amoebiasis.
• Autoimmune: Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) / Discoid Lupus.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Oral.
• Acute Malaria (The “4-2-2” Regimen):
  • Initial: 1000 mg (600 mg base).
  • + 6 Hours: 500 mg (300 mg base).
  • Day 2: 500 mg (300 mg base).
  • Day 3: 500 mg (300 mg base).
  • Total Dose: 2500 mg (1500 mg base) over 3 days.
• Prophylaxis: 500 mg (300 mg base) taken once weekly on the same day of the week. Start 1-2 weeks before travel.
• Lupus / RA: 250 mg daily (maintenance).
• Administration: Take with food to reduce nausea and stomach pain.

Safety Warnings:

• Retinopathy (Eye Toxicity): Long-term use (e.g., for Lupus) can cause irreversible retinal damage and blindness. Baseline and annual eye exams are mandatory.
• Pruritus (Itching): Intense itching is a very common side effect in Black/African patients. This is not an allergy but a genetic reaction.
• Psoriasis: Can precipitate a severe attack of psoriasis. Contraindicated in psoriatic patients.
• Cardiotoxicity: Can cause QT prolongation and arrhythmias. Caution with other heart drugs.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.

Commercial Inquiries

For hospital tenders, bulk export, or distributor pricing, please contact our export team.

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in