Description

Cinitapride Hydrogen Tartrate Film-Coated Tablets (1 mg)

Healthy Inc is a specialized global supplier and exporter of advanced gastroenterology, internal medicine, and targeted prokinetic therapeutics. We provide ultra-high-purity, kinetically stabilized Cinitapride Hydrogen Tartrate Film-Coated Tablets (1 mg), manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Next-Generation Prokinetic & 5-HT4 Agonist” is a massive-volume, high-margin export to GI clinics, surgical recovery centers, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, safer intervention for Gastroesophageal Reflux Disease (GERD) and functional dyspepsia.

Product Overview

This highly advanced formulation operates as a sophisticated “accelerator” for the digestive tract. It physically coordinates the contractions of the stomach and esophagus, ensuring that food and acid move downward into the intestines rather than refluxing upward or sitting stagnant in the stomach.

The “Triple-Serotonergic & Prokinetic” Specialist:

• Mechanism 1 (The 5-HT4 “Accelerator” Agonism): Cinitapride is a potent agonist of 5-HT4 receptors in the gut wall. Stimulating these receptors triggers a massive release of acetylcholine, which violently increases the pressure of the Lower Esophageal Sphincter (LES) and forces the stomach to empty its contents rapidly. This is the definitive cure for “Heartburn” caused by a weak LES.
• Mechanism 2 (The 5-HT1/5-HT2 “Smoothing” Antagonism): Uniquely, Cinitapride also acts as an antagonist at 5-HT1 and 5-HT2 receptors. This dual-action “smooths” out the gut’s contractions, preventing the painful cramping or “spastic” motility often seen with older, less selective prokinetics.
• Mechanism 3 (The Blood-Brain Barrier Exclusion): Unlike Metoclopramide, Cinitapride does not easily cross the blood-brain barrier at therapeutic doses. This guarantees that patients receive profound gastric relief with an Absolute Low Risk of Extrapyramidal Symptoms (tremors, restlessness, or facial tics).

Technical & Logistics Specifications

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Micro-Dose Content Uniformity (CRITICAL COMPLIANCE): Cinitapride is an extremely potent 1mg molecule. A “hot spot” in a batch (where a tablet contains 2mg or 3mg) can trigger acute neurological distress. Our GI suites utilize multi-stage geometric dilution and advanced V-blender technology to guarantee 100% Content Uniformity. We provide global buyers with a product that delivers consistent, safe, and predictable gastric motility every time.

Therapeutic Indications

• Gastroesophageal Reflux Disease (GERD): Treatment of patients who fail to respond to Proton Pump Inhibitors (PPIs) alone.
• Functional Dyspepsia: Relief of early satiety, postprandial fullness, and bloating.
• Gastroparesis: Management of delayed gastric emptying (often associated with diabetes).

Dosage & Administration

• Standard Adult Dosing: 1 mg taken orally three times daily (TID).
• The “Pre-Meal” Mandate (CRITICAL): This tablet MUST be taken 15 to 30 minutes before meals. Taking it after eating renders the drug ineffective, as the “accelerator” must be in the system before the food enters the stomach.

Safety Warnings (CRITICAL):

• Neurological Alert: While rare, it can cause extrapyramidal reactions (tremors/spasms). Strictly contraindicated in patients with Parkinson’s Disease or a history of tardive dyskinesia.
• Cardiac Interaction: While safer than Cisapride, avoid use with strong CYP3A4 inhibitors (Ketoconazole, Erythromycin) which can spike blood levels.
• CNS Effects: May cause mild drowsiness or dizziness. Use with caution when driving.
• Gastrointestinal Obstruction: Strictly contraindicated if a mechanical bowel obstruction or perforation is suspected, as forcing motility against a blockage can be fatal.

Global Export & Contract Manufacturing Services

Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for advanced GI prokinetics and specialized FDCs. Whether you are a Government Tender Supplier for hospital chains in Africa or a B2B Pharma Marketplace partner in Latin America, we ensure secure, WHO-GMP compliant delivery.