Description
Chlorzoxazone, Ibuprofen & Paracetamol Tablets (250 mg / 400 mg / 325 mg)
Healthy Inc is a specialized global supplier and exporter of advanced orthopedics, sports medicine, and targeted musculoskeletal therapeutics. We provide ultra-high-purity, kinetically optimized Chlorzoxazone, Ibuprofen & Paracetamol Tablets, manufactured in WHO–GMP certified, high-capacity oral solid dosage facilities. This “Centrally Acting Muscle Relaxant & Dual-Analgesic FDC” is a massive-volume, highly strategic export to orthopedic clinics, trauma centers, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally preferred intervention for acute low back pain, muscle strains, and post-traumatic spasms.
Product Overview
This formulation operates as a coordinated, three-front assault on musculoskeletal trauma. It doesn’t just dull the pain; it physically unlocks the “Spasm-Pain-Spasm” cycle by paralyzing the hyperactive spinal reflexes while simultaneously neutralizing the chemical inflammatory fire.
The “Triple-Action Muscle Rescue” Specialist:
- Mechanism 1 (The Spinal Reflex Interrupter – Chlorzoxazone): Chlorzoxazone is a centrally acting skeletal muscle relaxant. It acts primarily at the level of the spinal cord and subcortical areas of the brain to inhibit multi-synaptic reflex arcs. This physically forces the “locked” muscle to relax, instantly increasing the patient’s range of motion.
- Mechanism 2 (The Peripheral Inflammatory Blockade – Ibuprofen): As a potent NSAID, Ibuprofen inhibits the COX-1 and COX-2 enzymes, halting the production of prostaglandins at the site of injury. This shuts down the swelling and throbbing pain at the source.
- Mechanism 3 (The Central Pain Threshold Elevator – Paracetamol): Paracetamol works synergistically with Ibuprofen by increasing the overall pain threshold in the central nervous system. This dual-analgesic effect provides “Total Pain Coverage,” allowing for lower doses of each drug and reducing the risk of systemic side effects.
Product Composition & Strength
We supply this product as a High-Density, Precision-Compressed Tablet, packed exclusively in secure, moisture-resistant Alu-PVC or Alu-Alu blister strips to ensure the stability of the large multi-API payload.
| Active Ingredient | Strength | Primary Clinical Function |
|---|---|---|
| Chlorzoxazone USP/BP | 250 mg | The Muscle Relaxant Anchor: Targets the spinal cord to inhibit the reflexes driving the muscle spasm. |
| Ibuprofen USP/BP | 400 mg | The Anti-Inflammatory Payload: Blocks prostaglandin synthesis to reduce tissue swelling and peripheral pain. |
| Paracetamol (Acetaminophen) USP/BP | 325 mg | The Central Analgesic Booster: Synergistically raises the pain threshold for rapid symptomatic relief. |
| Excipients | Microcrystalline Cellulose / Sodium Starch Glycolate / Povidone K-30 / Magnesium Stearate / Polymeric Film Coat | Diluent / Superdisintegrant / Binder / Lubricant (Engineered specifically utilizing High-Pressure Rotary Compression to manage the massive ~1000mg tablet weight while ensuring the tablet remains swallowable and shatters instantly in gastric fluid). |
*Pack Sizes: 10×10 Blisters (Optimized specifically for 5-day to 10-day acute injury recovery cycles).
Technical & Logistics Specifications
| HS Code | 3004.90.99 (Medicaments containing other active substances – Orthopedics/Analgesics) |
| CAS Numbers | 95-25-0 (Chlorzoxazone) / 15687-27-1 (Ibuprofen) / 103-90-2 (Paracetamol) |
| Dosage Form | Film-Coated Tablet (Immediate Release) |
| Packaging | Alu-PVC or Alu-Alu Blisters. Protects the large-format tablets from environmental humidity across Zone IVb tropical climates. |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Bilayer/High-Density Engineering & Dissolution Accuracy (CRITICAL COMPLIANCE): Compressing three powerful APIs into one tablet is a challenge of mass and kinetics. If the tablet is too large, patient compliance drops; if it’s too dense, it won’t dissolve. Our orthopedic suites utilize advanced High-Shear Granulation to densify the powder, ensuring a streamlined tablet that delivers 100% of its payload within 20 minutes. We provide global buyers with a consistent, bioequivalent “Heavyweight” FDC.
Therapeutic Indications
- Acute Musculoskeletal Pain: Treatment of severe muscle spasms associated with low back pain (Lumbago), neck pain (Torticollis), and sciatica.
- Traumatic Injuries: Management of pain and spasms following sprains, strains, or fractures.
- Post-Surgical Recovery: Relief of muscle-driven pain following orthopedic procedures.
Dosage & Administration
- Standard Adult Dosing: 1 tablet taken three times daily (TID).
- The “Full Stomach” Mandate (CRITICAL): This tablet MUST be taken after a full meal. Ibuprofen is highly gastro-erosive; taking this on an empty stomach can lead to acute gastric ulceration or bleeding.
Safety Warnings (CRITICAL):
- Hepatotoxicity Warning (Chlorzoxazone Alert): Rare but severe liver damage has been reported with Chlorzoxazone. Therapy must be stopped if the patient develops yellowing of the eyes/skin (Jaundice).
- Gastrointestinal Risk: Ibuprofen carries a “Black Box Warning” for serious GI bleeding and perforation. Strictly contraindicated in patients with active peptic ulcers.
- CNS Depression: Chlorzoxazone causes drowsiness. Patients must not drive or consume alcohol, as it will violently increase the sedative effect.
- Cardiovascular Risk: Long-term NSAID use increases the risk of heart attack and stroke.
Global Export & Contract Manufacturing Services
Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for heavy-duty Orthopedic FDCs. Whether you are a Government Tender Supplier for emergency trauma centers in Africa or a B2B Pharma Marketplace partner in Latin America, we ensure secure, WHO-GMP compliant delivery.
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