Cefixime Tablets

Description

Cefixime Film-Coated Tablets (200 mg / 400 mg)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, internal medicine, and targeted 3rd-generation cephalosporin therapeutics. We provide ultra-high-purity, kinetically optimized Cefixime Tablets (200 mg / 400 mg), manufactured in WHO–GMP certified, dedicated Beta-Lactam high-containment facilities. This “3rd-Generation Cephalosporin & Enteric Specialist” is a massive-volume, highly strategic export to infectious disease clinics, pediatric networks, and government health ministries, serving as the globally mandated intervention for Typhoid Fever, Urinary Tract Infections (UTI), and acute respiratory exacerbations.

Product Overview

This formulation operates as a structural saboteur of resilient Gram-negative bacteria. Cefixime is uniquely recognized for its high stability against $\beta$-lactamase enzymes and its exceptional penetration into the gallbladder and intestinal tissues, making it the premier oral treatment for Enteric Fever.

• Mechanism 1 (The PBP-3 Blockade): Cefixime binds aggressively to Penicillin-Binding Proteins (PBPs), specifically targeting PBP-3 of Gram-negative bacilli. This halts the final transpeptidation step of peptidoglycan synthesis, causing the bacterial cell wall to lose its integrity and explode under osmotic pressure.

• Mechanism 2 (The Enteric Specialist): Unlike other cephalosporins, Cefixime achieves very high concentrations in the bile and intestinal mucosa. This makes it devastatingly effective against Salmonella typhi, the causative agent of Typhoid Fever, which often colonizes the gallbladder.

• Mechanism 3 (The 3rd-Gen Spectrum): It provides superior coverage against Haemophilus influenzae, Moraxella catarrhalis, and Neisseria gonorrhoeae, pathogens that have developed resistance to older 1st and 2nd-generation antibiotics.

Product Composition & Strength

We supply this product as a Precision-Blended, High-Bioavailability Tablet, packed exclusively in high-barrier Alu-Alu blister strips to ensure the stability of the trihydrate salt.

Technical & Logistics Specifications

• HS Code: 3004.20.00 (Medicaments containing antibiotics)

• CAS Number: 79350-37-1 (Cefixime) / 125110-14-7 (Cefixime Trihydrate)

• Dosage Form: Film-Coated Tablet (Immediate Release)

• Packaging: Alu-Alu Blisters (STRICTLY MANDATORY). Cefixime is sensitive to moisture and light. Alu-Alu packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Dedicated Beta-Lactam Isolation: To eliminate the risk of life-threatening cross-contamination, production occurs in Strictly Isolated Beta-Lactam Blocks with independent HVAC systems and HEPA filtration.

• Isomeric Purity: We utilize advanced HPLC to ensure absolute chemical purity of the trihydrate form, providing global buyers with a consistent, high-potency product.

Dosage & Administration

• Standard Adult Dosing: 400 mg once daily or 200 mg twice daily (BID) for 7 to 14 days.

• Flexible Administration: The absorption of Cefixime is not significantly affected by food, though it may be taken with meals to minimize potential gastrointestinal upset.

• The “Typhoid Protocol”: Treatment for Enteric Fever typically requires a full 14-day course to prevent the development of a chronic carrier state.

Safety Warning: Strictly contraindicated in patients with cephalosporin hypersensitivity. 10% cross-reactivity risk in penicillin-allergic patients. Adjust dosage in patients with severe renal impairment ($CrCl < 20$ mL/min).

Global Export & Contract Manufacturing

Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Antibiotics. Whether you are a Government Tender Supplier for typhoid programs in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery.