Description

Sildenafil Citrate Tablets

Healthy Inc is a specialized global supplier and exporter of phosphodiesterase type 5 (PDE5) inhibitors. We provide high-purity Sildenafil Citrate Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Vascular Dilator” is a top export to urology clinics, men’s health centers, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the first-line oral therapy for Erectile Dysfunction (ED) and Pulmonary Arterial Hypertension (PAH).

Product Overview

This formulation contains Sildenafil Citrate, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

The “Flow Enhancer” Specialist:

• Mechanism (The NO-cGMP Pathway): Sexual stimulation releases Nitric Oxide (NO) in the corpus cavernosum of the penis. NO activates the enzyme guanylate cyclase, which increases levels of cyclic GMP (cGMP). Sildenafil inhibits the enzyme PDE5, which is responsible for breaking down cGMP.
• Result: By preventing the breakdown of cGMP, Sildenafil prolongs smooth muscle relaxation and increases blood flow into the penis, facilitating and maintaining an erection sufficient for sexual activity.
• Pulmonary Action: In the lungs, PDE5 is also present. Sildenafil relaxes the pulmonary vasculature, lowering blood pressure in the pulmonary arteries (used in PAH).

Product Composition & Strength

We supply this product as Film Coated Tablets (typically Blue, Diamond-Shaped). The coating is essential to mask the extremely bitter taste of the citrate salt.

*Pack Sizes: Blister packs of 1s, 4s (Wallet Pack), 10s, or Bulk HDPE Jars of 100s.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Dissolution Kinetics: Sildenafil has pH-dependent solubility (low in neutral pH). Our formulation uses specific acidifying agents and super-disintegrants to ensuring rapid onset of action (Tmax ~30-60 minutes).
• Color Consistency: The iconic “Blue Pill” requires precise lake color blending. We ensure uniform color distribution to prevent mottling, maintaining the premium aesthetic expected by patients.

Therapeutic Indications (Human Use)

Indicated for the treatment of vascular disorders:

• Erectile Dysfunction (ED): Inability to achieve or maintain an erection sufficient for sexual performance.
• Pulmonary Arterial Hypertension (PAH): (Usually marketed as 20 mg tablets) Improves exercise ability and delays clinical worsening (WHO Functional Class II-III).

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Oral.
• For ED (Adults): 50 mg taken approximately 1 hour before sexual activity. Dose may be increased to 100 mg or decreased to 25 mg based on efficacy and tolerance.
• Frequency: Maximum recommended dosing frequency is once per day.
• Administration: Effective only with sexual stimulation. Taking with a high-fat meal delays absorption and onset of action by up to 60 minutes.

Safety Warnings:

• Nitrates Contraindication (Life-Threatening): DO NOT USE if taking organic nitrates (Nitroglycerin, Isosorbide Mononitrate) for chest pain. The combination causes a severe, fatal drop in blood pressure.
• Priapism: Erections lasting >4 hours require immediate medical attention to prevent permanent tissue damage.
• Vision Changes: Can cause temporary “Blue Vision” (cyanopsia) due to PDE6 inhibition in the retina. Stop if sudden vision loss occurs (NAION).
• Cardiovascular Health: Sexual activity carries cardiac risk. Use caution in patients with recent heart attack or stroke.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.