Description

Vitamin A Soft Gelatin Capsules

Healthy Inc is a specialized global supplier and exporter of essential micronutrients and public health therapeutics. We provide high-purity Vitamin A Soft Gelatin Capsules (100,000 IU), manufactured in WHO–GMP certified dedicated softgel facilities. This “Fat-Soluble Megadose” is a massive-volume, high-priority export to NGOs, global health initiatives, pediatric clinics, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the foundational intervention for preventing childhood xerophthalmia (night blindness) and reducing mortality from severe pediatric infections.

Product Overview

This formulation contains Vitamin A (as Retinyl Palmitate or Retinyl Acetate), an essential, fat-soluble retinoid.

The “Epithelial & Immunological” Specialist:

• Mechanism (Visual Cycle & Gene Expression): Vitamin A is critical for vision. It is converted in the retina to 11-cis-retinal, which binds to opsin to form rhodopsin, the light-absorbing molecule essential for low-light (scotopic) vision. Systemically, its active metabolite (retinoic acid) binds to nuclear receptors (RAR/RXR) to regulate the transcription of over 500 genes, driving the proper differentiation of epithelial tissues and mucous membranes.
• Immune System Competence: It is widely known as the “anti-infective” vitamin. By maintaining the physical barrier of mucosal epithelia (in the respiratory and gastrointestinal tracts) and supporting the function of macrophages and T-cells, mega-doses drastically reduce the severity and mortality rates of diseases like Measles and severe diarrhea in malnourished children.
• The “Nip-and-Squeeze” Delivery: Because 100,000 IU is the exact WHO-mandated dose for infants aged 6 to 11 months, these softgels are specifically engineered with a specialized “nipple” end. Healthcare workers simply cut the tip and squeeze the stabilized oil directly into the infant’s mouth.

Product Composition & Strength

We supply this product as a Liquid-Filled Soft Gelatin Capsule (traditionally colored blue for the 100,000 IU strength to adhere to global visual identification standards), packed in bulk jars for mass-immunization campaigns.

*Pack Sizes: Bulk HDPE Jars of 100 or 500 Capsules. (Standardized for large-scale pediatric outreach programs).

Technical & Logistics Specifications

Critical data for NGO Procurement Boards and Pharmaceutical Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Lipid Stabilization & Nitrogen Purging: Vitamin A is highly susceptible to oxidative degradation when exposed to air and light. Our manufacturing process utilizes strictly controlled nitrogen purging during the encapsulation of the lipid matrix, combined with the addition of Vitamin E (dl-Alpha Tocopherol) as an antioxidant, ensuring the 100,000 IU strength remains completely viable over a 24 to 36-month shelf life in harsh, tropical field conditions.
• Softgel Shell Integrity: The gelatin shell is calibrated for elasticity, ensuring it does not become brittle in cold climates or melt in extreme heat, allowing for reliable “nip-and-squeeze” administration in rural environments.

Therapeutic Indications (Human Use)

Indicated for public health supplementation and the clinical treatment of severe deficiencies:

• Routine Public Health Supplementation: Prevention of Vitamin A Deficiency (VAD) in infants (6-11 months) in endemic areas to prevent night blindness (xerophthalmia) and corneal ulceration (keratomalacia).
• Measles Adjunct Therapy: Administered to children diagnosed with measles to drastically reduce the risk of severe complications, blindness, and death.
• Severe Malnutrition: Treatment of severe acute malnutrition (SAM) where micronutrient stores are severely depleted.

Dosage & Administration

Recommended Dosage (Strictly as per WHO/UNICEF Guidelines):

• Administration (Infants 6-11 months): 100,000 IU (One Capsule) given as a single oral dose every 4 to 6 months.
• Method of Delivery: The capsule tip is cut with clean scissors, and the liquid contents are squeezed directly onto the back of the infant’s tongue. The empty gelatin shell is then discarded.
• Measles Treatment (Infants 6-11 months): One dose of 100,000 IU administered immediately upon diagnosis, followed by a second identical dose the next day.

Safety Warnings (CRITICAL):

• Teratogenic Risk (Pregnancy Contraindication): Megadoses of Vitamin A (like 100,000 IU or 200,000 IU) are heavily teratogenic and MUST NEVER be given to pregnant women, as they will cause severe fetal malformations. (Standard daily prenatal vitamins contain safe, drastically lower doses, typically <10,000 IU).
• Hypervitaminosis A (Toxicity): Because it is a fat-soluble vitamin, excess amounts are stored in the liver, not excreted in the urine. Over-administration can cause acute toxicity (bulging fontanelles in infants, severe vomiting, intracranial hypertension) or chronic liver damage. Strictly adhere to the 4-6 month dosing intervals.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Essential Micronutrients, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable NGO Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.