Description

Telmisartan Tablets

Healthy Inc is a specialized global supplier and exporter of advanced cardiovascular, metabolic, and nephroprotective therapeutics. We provide ultra-high-purity, structurally stabilized Telmisartan Tablets (20 mg / 40 mg / 80 mg), manufactured in WHO–GMP certified, high-capacity oral solid dosage facilities. This “Premium Angiotensin II Receptor Blocker (ARB)” is a massive-volume, essential export to cardiology centers, primary care networks, specialized hypertension clinics, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted, first-line intervention for essential hypertension and cardiovascular risk reduction.

Product Overview

This formulation contains Telmisartan, a highly lipophilic, non-peptide angiotensin II receptor antagonist that fundamentally outperforms older antihypertensives through superior pharmacokinetics and dual-action metabolic benefits.

The “24-Hour CV Protection & Metabolic” Specialist:

• Mechanism 1 (The AT1 Receptor Blockade): Telmisartan aggressively and selectively binds to the AT1 receptor subtype, violently displacing Angiotensin II. By blocking this powerful hormone, it stops the blood vessels from constricting and halts the release of aldosterone (which causes water retention). This results in a massive, sustained drop in systemic blood pressure and a severe reduction in workload on the heart.
• The “24-Hour True Trough” Advantage: Telmisartan has a terminal elimination half-life of 24 hours—the longest of any ARB on the global market. This guarantees true, uninterrupted, round-the-clock blood pressure control with a single daily dose, specifically blunting the dangerous “early morning BP surge” when heart attacks and strokes are most likely to occur.
• Mechanism 2 (The PPAR-Gamma Metabolic Bonus): Uniquely among ARBs, Telmisartan acts as a partial agonist of the PPAR-gamma receptor. This is the same receptor targeted by diabetes drugs (like Pioglitazone). By activating it, Telmisartan actively improves cellular insulin sensitivity and lipid profiles, making it the absolute gold-standard blood pressure medication for patients with Metabolic Syndrome or Type 2 Diabetes.

Product Composition & Strength

We supply this product as a Precision-Blended Uncoated Tablet, packed exclusively in highly secure, moisture-resistant Alu-Alu blister strips. The formulation utilizes specialized alkalizing agents to ensure the highly insoluble API rapidly dissolves in the gastrointestinal tract.

*Pack Sizes: 10×10 or 10×14 Alu-Alu Blisters (Optimized specifically for 30-day chronic cardiology dispensing regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Cardiology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Meglumine Stabilization Engineering: Telmisartan is practically insoluble in water, which can lead to therapeutic failure if poorly manufactured. Our facilities utilize a highly specialized alkalizing technique (incorporating Meglumine and Sodium Hydroxide) during the high-shear wet granulation phase. This forcefully converts the Telmisartan into a highly soluble salt within the tablet matrix, guaranteeing immediate dissolution and highly predictable bioavailability upon ingestion.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of severe cardiovascular and hemodynamic strain:

• Essential Hypertension: Treatment of high blood pressure in adults, either as monotherapy or in combination with other antihypertensive agents (like Amlodipine or Hydrochlorothiazide).
• Cardiovascular Risk Reduction: Reduction of the risk of myocardial infarction (heart attack), stroke, or death from cardiovascular causes in patients 55 years of age or older at high risk of developing major cardiovascular events who are unable to tolerate ACE inhibitors.

Dosage & Administration

Recommended Dosage (Strictly as per Cardiologist/Physician Guidelines):

• Standard Adult Dosing: The usual starting dose is 40 mg once a day. Blood pressure response is dose-related over the range of 20 to 80 mg.
• Administration: Must be taken orally once daily. Can be taken with or without food.
• Hepatic Impairment Rule: Telmisartan is cleared almost entirely by biliary excretion. In patients with mild to moderate hepatic impairment, the daily dose must not exceed 40 mg.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• BLACK BOX WARNING (Fetal Toxicity): Drugs that act directly on the renin-angiotensin system (RAAS) can cause catastrophic injury and death to the developing fetus. When pregnancy is detected, Telmisartan MUST be discontinued as soon as possible.
• Dual RAAS Blockade Contraindication: Co-administering Telmisartan with an ACE inhibitor (like Ramipril) or Aliskiren is heavily discouraged. It massively increases the risk of severe hypotension, dangerous hyperkalemia (high potassium), and acute renal failure without offering additional cardiovascular benefits.
• Hyperkalemia: Because it blocks aldosterone, Telmisartan causes the kidneys to retain potassium. Serum potassium levels must be monitored, especially in patients with severe heart failure or those taking potassium-sparing diuretics (like Spironolactone).
• Hypotension in Volume-Depleted Patients: In patients who are volume-depleted (e.g., from high-dose diuretics or severe diarrhea), symptomatic hypotension may occur. Correct volume status prior to initiation.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Cardiovascular and Metabolic Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for national hypertension programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.