Description

Tamsulosin Hydrochloride MR Tablets (0.4 mg)

Healthy Inc is a specialized global supplier and exporter of advanced urological, nephrological, and men’s health therapeutics. We provide ultra-high-purity, kinetically advanced Tamsulosin Hydrochloride Modified-Release (MR) Tablets (0.4 mg), manufactured in WHO–GMP certified, high-precision advanced polymer-matrix facilities. This “Next-Generation Uro-Selective Alpha-Blocker” is a highly lucrative, premium export to urology centers, geriatric care networks, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted, food-independent intervention for the symptomatic relief of Benign Prostatic Hyperplasia (BPH).

Product Overview

This highly advanced formulation contains Tamsulosin Hydrochloride, a highly uro-selective alpha-1A blocker, engineered into a state-of-the-art prolonged-release tablet matrix that fundamentally outperforms older pellet-in-capsule generic formulations.

The “Food-Independent Continuous Release” Specialist:

• Mechanism (The Alpha-1A Blockade): Tamsulosin selectively binds to the alpha-1A adrenergic receptors densely located in the prostate gland and bladder neck. By blocking these receptors, it relaxes the smooth muscle, instantly relieving the physical obstruction of the urethra and restoring strong, normal urinary flow.
• The Advanced Gel-Matrix Advantage: Standard Tamsulosin capsules must be taken exactly 30 minutes after a meal; otherwise, the drug absorbs too fast, causing the patient’s blood pressure to violently crash. Our Modified-Release (MR) Tablet utilizes an advanced non-ionic polymer matrix. Upon entering the gut, the tablet rapidly hydrates to form a dense gel. The active ingredient slowly and evenly diffuses out of this gel over a full 24 hours.
• The Clinical Upgrade (Zero Peak-and-Trough): Because the gel-matrix release is completely independent of stomach acid or food, patients can take this tablet at any time of day, with or without meals. It provides a significantly flatter pharmacokinetic profile (Cmax) than the capsule, drastically reducing the risk of dizziness, fainting (syncope), and orthostatic hypotension.

Product Composition & Strength

We supply this product as a Precision-Engineered Gel-Matrix Film-Coated Tablet, packed exclusively in highly secure, moisture-resistant Alu-Alu blister strips to ensure the absolute stability of the hygroscopic polymers.

*Pack Sizes: 10×10 or 10×15 Alu-Alu Blisters (Optimized specifically for strict 30-day chronic urology adherence regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Urology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Macrogol Matrix Kinetic Engineering: Formulating an ultra-low dose (0.4 mg) into a massive, 24-hour continuous-release polymer matrix requires apex-level pharmaceutical manufacturing. Our facilities utilize advanced high-shear granulation and strictly validated multipoint HPLC dissolution profiling to guarantee that every single tablet forms the critical hydrogel instantly upon ingestion, preventing “dose dumping” even in an empty stomach.

Therapeutic Indications (Human Use)

Indicated for the comprehensive, highly tolerable management of lower urinary tract symptoms (LUTS):

• Benign Prostatic Hyperplasia (BPH): Treatment of the signs and symptoms of BPH (e.g., urinary frequency, urgency, weak stream, and nocturia) in patients requiring a flatter pharmacokinetic profile than standard capsules provide.

Dosage & Administration

Recommended Dosage (Strictly as per Urologist Guidelines):

• Standard Adult Dosing: 0.4 mg administered orally once daily.
• Administration (THE FOOD-INDEPENDENT ADVANTAGE): Unlike older capsule formulations, this Modified-Release Tablet can be taken independently of food intake. It can be taken at any time of day, but should preferably be taken at the same time each day to maintain steady blood levels.
• Swallowing Protocol (CRITICAL): The tablet MUST be swallowed whole with a glass of water. It must never be crushed, chewed, or divided, as this will instantly destroy the structural integrity of the gel matrix, causing a rapid, dangerous overdose of the alpha-blocker.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Intraoperative Floppy Iris Syndrome (IFIS – BLACK BOX EQUIVALENT): Tamsulosin actively blocks alpha-receptors in the eye’s iris. During cataract surgery, this can cause the iris to become completely flaccid, severely complicating the surgery. Patients MUST inform their ophthalmologist that they are taking Tamsulosin before undergoing any eye surgery.
• Orthostatic Hypotension: While the advanced tablet matrix significantly reduces the risk compared to standard capsules, patients may still experience a mild drop in blood pressure upon standing.
• Ejaculatory Dysfunction: A common side effect is abnormal ejaculation (such as retrograde ejaculation). Patients should be counseled that this is harmless and reversible.
• Sulfa Allergy Caution: Tamsulosin contains a sulfonamide moiety. Use with caution in patients with known severe sulfa allergies.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Urological Matrix Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for geriatric care programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.