Promethazine Syrup

Description

Promethazine Hydrochloride Oral Syrup (5 mg / 5 ml)

Healthy Inc is a specialized global supplier and exporter of advanced antihistamines, pediatric medicine, and travel health therapeutics. We provide ultra-high-purity, kinetically stable Promethazine Syrup, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “First-Generation Phenothiazine Antihistamine” is a massive-volume strategic export to retail pharmacies, pediatric hospitals, and international B2B distributors, serving as the globally preferred intervention for the symptomatic relief of allergies, motion sickness, and post-operative nausea.

Product Overview

This formulation operates as a “Triple-Action Neurological Stabilizer.” It physically targets the brain’s allergy, vomiting, and wakefulness centers to provide comprehensive relief.

• Mechanism 1 (Potent H1-Antagonism): Promethazine physically blocks H1-histamine receptors. It chemically stops the “immediate” allergic response—sneezing, itching, and runny nose.

• Mechanism 2 (Antiemetic Effect): It physically inhibits the Chemoreceptor Trigger Zone (CTZ) in the brain, making it exceptionally effective at stopping vomiting and nausea.

• Mechanism 3 (Central Sedation): Unlike second-generation drugs, it physically crosses the blood-brain barrier to provide Sedation, which is clinically used to calm children during illness or before minor procedures.

Product Composition & Strength

We supply this product as a Sterile, Clear to Pale Straw-Colored Liquid, optimized for high stability and pediatric compliance.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments acting on the nervous system / Others)

• CAS Number: 58-33-3 (Promethazine Hydrochloride)

• Dosage Form: Oral Liquid (Syrup)

• Packaging: 60 ml / 100 ml Amber PET or Glass Bottles. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Oxidation Protection: Promethazine is physically sensitive to light and air. Our manufacturing process utilizes Nitrogen Blanketing during filling and light-protected Amber Bottles to ensure 100% chemical potency.

• Aseptic Liquid Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for pediatric use.

• Non-Crystallizing Formula: We ensure a consistent physical viscosity that prevents “bottleneck crystallization,” ensuring the exact 5mg dose is delivered in every 5ml spoon.

Primary Indications

• Pediatrics: Management of Seasonal Allergic Rhinitis, Urticaria (Hives), and allergic conjunctivitis.

• Travel Medicine: Prevention and treatment of Motion Sickness (Travel sickness).

• Surgery: Pre-operative and post-operative Sedation and management of nausea.

• Dermatology: Relief of severe itching (Pruritus) associated with skin disorders.

Dosage & Administration

• Allergies: Typically 0.125 mg/kg body weight three times daily, or as a single larger dose at bedtime.

• Motion Sickness: Dose should physically be taken 30 to 60 minutes before travel.

• Administration: Can be taken physically with or without food.

• Nighttime Focus: It is physically best to give the dose in the evening if daytime drowsiness is not desired.

Safety Warning: For Oral Use Only. Respiratory Note: Promethazine may physically cause Respiratory Depression; use with extreme caution in children with asthma. Sun Note: It may physically cause Photosensitivity; keep the child out of direct sunlight. Contraindication: STRICT BOXED WARNING: Do not use in children under 2 years of age due to the risk of fatal respiratory depression. Do not use in patients with known hypersensitivity to Phenothiazines.

Global Export & Contract Manufacturing

Healthy Inc is a premier Antihistamine and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Promethazine syrups. Whether you are a National Pediatric Brand in the CIS or a B2B Pharma Marketplace partner in Africa, the Middle East, or SE Asia, we ensure secure, WHO-GMP compliant delivery.