Description

Natural Micronized Progesterone SR Tablets (200 mg / 300 mg / 400 mg)

Healthy Inc is a specialized global supplier and exporter of advanced gynecological, obstetric, and fertility therapeutics. We provide ultra-high-purity, kinetically sustained Natural Micronized Progesterone Sustained-Release (SR) Tablets, manufactured in WHO–GMP certified, high-containment dedicated hormonal oral solid dosage facilities. This “Bio-Identical Pregnancy Guardian” is a premium, high-value export to IVF centers, maternal health NGOs, obstetrics/gynecology networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated intervention for Luteal Phase Support, the prevention of recurrent miscarriage, and advanced Hormone Replacement Therapy (HRT).

Product Overview

This highly advanced formulation contains Natural Micronized Progesterone, a bio-identical hormone that perfectly mirrors the progesterone naturally produced by the human ovaries, fundamentally avoiding the severe side effects associated with synthetic progestins.

The “Endometrial Receptivity & Sustained-Release” Specialist:

• Mechanism 1 (The Uterine Incubator): For an embryo to successfully implant and survive, the lining of the uterus (the endometrium) must be thick, vascularized, and highly receptive. Progesterone is the absolute master hormone that prepares and maintains this lining. In IVF protocols, or in women with Luteal Phase Defect, natural progesterone production is often insufficient. This medication floods the uterine receptors, physically transforming the endometrium to sustain early pregnancy until the placenta can take over hormone production.
• Mechanism 2 (The Uterine Relaxant): Beyond supporting the uterine lining, massive levels of progesterone are required to keep the uterine muscles completely relaxed. A sudden drop in progesterone triggers violent uterine contractions. By maintaining high, stable levels of this hormone, it effectively prevents the uterus from contracting, acting as a critical shield against preterm birth and threatened miscarriage.
• The “Micronized SR” Advantage (CRITICAL): Standard oral progesterone has terrible bioavailability; the liver destroys over 90% of it immediately (first-pass metabolism). We utilize Ultra-Micronization to violently reduce the particle size of the API, vastly increasing its surface area for rapid absorption. Furthermore, our Sustained-Release (SR) polymer matrix slowly trickles the hormone into the bloodstream over 24 hours. This completely prevents the massive, rapid hormone spikes that cause extreme dizziness and fatigue, ensuring perfect blood levels with just a single daily dose.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Gynecology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Dedicated Hormonal Isolation Facilities (CRITICAL COMPLIANCE): Progesterone is a highly potent steroid hormone. If manufactured in a standard facility, the microscopic API dust will inevitably cross-contaminate other drugs (like cardiovascular or pediatric meds), leading to catastrophic regulatory shutdowns. Our manufacturing occurs in strict, dedicated hormonal isolation blocks operating under severe negative pressure with advanced multi-stage HEPA filtration. This guarantees zero cross-contamination and ensures total safety for our facility operators.

Therapeutic Indications (Human Use)

Indicated for the targeted management of severe gynecological, obstetric, and fertility dysfunctions:

• Assisted Reproductive Technology (ART) / IVF: Luteal phase support for women undergoing IVF or embryo transfer protocols.
• Obstetrics: Prevention of recurrent pregnancy loss or threatened miscarriage in women with proven progesterone deficiency. Prevention of preterm birth in women with a singleton pregnancy and a history of spontaneous preterm birth.
• Gynecology: Treatment of secondary amenorrhea and dysfunctional uterine bleeding. Endometrial protection in women receiving estrogen for Hormone Replacement Therapy (HRT).

Dosage & Administration

Recommended Dosage (Strictly as per Obstetrician/Endocrinologist Guidelines):

• Administration (THE BEDTIME RULE): Even with sustained-release technology, oral progesterone interacts with GABA receptors in the brain, causing significant sedation, drowsiness, and dizziness. Therefore, the total daily dose MUST be taken at bedtime.
• Food Interaction: Taking oral progesterone with food massively increases its absorption (by up to 2-fold). Patients should take it consistently either with or without food to prevent erratic hormonal blood levels. Tablets must be swallowed whole to preserve the SR matrix.
• Vaginal Administration (Off-Label / IVF Protocol): In many advanced IVF protocols, clinicians may direct the patient to insert the micronized tablet/capsule vaginally to achieve massive localized concentrations directly in the uterus while bypassing liver metabolism entirely.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Thromboembolic Risk (Blood Clots): While natural bio-identical progesterone is significantly safer than synthetic progestins, there is still a baseline risk of venous thromboembolism (DVT, pulmonary embolism) or arterial thrombosis (stroke, myocardial infarction). Discontinue immediately if symptoms of a blood clot occur.
• Hepatic Dysfunction: Contraindicated in patients with severe hepatic impairment or disease, as the liver will fail to clear the massive hormonal load, leading to systemic toxicity.
• Undiagnosed Vaginal Bleeding: Strictly contraindicated in patients with undiagnosed abnormal genital bleeding or known/suspected malignancy of the breast or genital organs.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Gynecology Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Hormonal and IVF Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for maternal health programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.