Permethrin Cream

Description

Permethrin Cream (5.0% w/w)

Healthy Inc is a specialized global supplier and exporter of advanced dermatology, infectious disease, and targeted antiparasitic therapeutics. We provide ultra-high-purity, kinetically stabilized Permethrin Cream, manufactured in WHO–GMP certified, high-precision specialized topical facilities. This “Synthetic Pyrethroid” is a massive-volume strategic export to retail pharmacies, public health agencies, and international NGOs, serving as the globally mandated first-line intervention for Scabies and Pediculosis (Lice).

Product Overview

This formulation operates as a “Nervous System Disruptor.” It is highly toxic to parasites but physically safe for humans because our bodies rapidly metabolize and break it down.

• Mechanism 1 (Sodium Channel Blockade): Permethrin physically binds to the Voltage-Gated Sodium Channels in the nerve cell membranes of the parasite.

• Mechanism 2 (Neurotoxic Paralysis): By physically preventing the “resetting” of these channels, it causes a continuous influx of sodium, leading to delayed repolarization. This results in the rapid paralysis and death of the Sarcoptes scabiei mite.

• Mechanism 3 (Ovicidal Support): While primarily killing the adult mites, the cream remains in the skin long enough to significantly impair the survival of any newly hatching eggs.

Product Composition & Strength

We supply this product in a Smooth, Non-Staining Vanishing Cream Base, optimized for whole-body application without leaving a sticky residue.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments acting as antiparasitics/dermatologicals)

• CAS Number: 52645-53-1 (Permethrin)

• Dosage Form: Topical Cream (O/W Emulsion)

• Packaging: Laminated Aluminum or Plastic Tubes (15g / 30g / 60g). For Scabies, a 30g tube is the standard single-dose adult requirement. Our high-barrier packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• API Purity Standards: We utilize Pharmacopoeial Grade (USP/BP) Permethrin, ensuring the Cis:Trans isomer ratio is perfectly balanced for maximum efficacy and minimal skin irritation.

• Aseptic Compounding: We utilize Automated Closed-Loop Systems to ensure the cream is free from microbial contaminants, ensuring safety even when applied to skin that has been damaged by intense scratching.

Primary Indications

• Public Health: Treatment of Scabies (Sarcoptes scabiei infestations).

• Dermatology: Management of Crusted (Norwegian) Scabies (often in combination with oral therapy).

• Pediatrics: Treatment of head lice and body lice in children and adults.

Dosage & Administration (The “Neck-Down” Protocol)

• Standard Regimen: A single application is usually curative.

• Administration: Thoroughly massage the cream into the skin from the neck down to the soles of the feet, including between fingers and toes, underarms, and groin.

• Duration: Leave the cream on for 8 to 14 hours (usually overnight) before washing it off thoroughly.

• Partner Protocol: To prevent reinfection, all household members and close contacts should be treated simultaneously.

Safety Warning: External Use Only. Avoid contact with eyes and mucous membranes. Post-Scabetic Itch: Patients should be informed that itching may continue for 2–4 weeks after the mites are dead; this is an allergic reaction to the debris, not a treatment failure. Contraindication: Do not use in infants under 2 months of age.

Global Export & Contract Manufacturing

Healthy Inc is a premier Antiparasitic and Dermatology Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume parasiticidal topicals. Whether you are a National Health Ministry in Africa or a B2B Pharma Marketplace partner in the CIS, South East Asia, or LATAM, we ensure secure, WHO-GMP compliant delivery.

Commercial Inquiries:

WhatsApp/Call: +91 7710003340

Email: info@healthyinc.co.in