Description

Orlistat Capsules / Tablets (60 mg / 120 mg)

Healthy Inc is a specialized global supplier and exporter of advanced metabolic, endocrinology, and weight-management therapeutics. We provide ultra-high-purity, kinetically stabilized Orlistat Hard Gelatin Capsules (containing micro-pellets) / Film-Coated Tablets (60 mg / 120 mg), manufactured in WHO–GMP certified, strictly temperature-controlled biological extraction facilities. This “Non-Systemic Gastrointestinal Lipase Inhibitor” is a massive-volume, highly lucrative export to bariatric centers, endocrinology clinics, retail pharmacy networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, cardioprotective intervention for clinical obesity and metabolic syndrome reversal.

Product Overview

This highly advanced formulation contains Orlistat, a saturated derivative of lipstatin. It acts as an elite, highly targeted “lipid shield,” physically preventing the human body from absorbing a significant portion of the fat consumed in the daily diet without altering brain chemistry.

The “Non-Systemic Caloric Blocker” Specialist:

• Mechanism 1 (The Pancreatic Lipase Blockade): For dietary fat (triglycerides) to be absorbed into the bloodstream, it must first be broken down by enzymes called gastric and pancreatic lipases. Orlistat aggressively and covalently binds to these enzymes in the stomach and small intestine, rendering them completely inactive. Consequently, approximately 30% of the fat consumed in a meal passes through the digestive tract undigested and is naturally excreted in the feces, creating a massive, sustained caloric deficit.
• Mechanism 2 (The Behavioral Modifier / “Fat Penalty”): Beyond its chemical mechanism, Orlistat exerts a powerful psychological effect. If a patient consumes a meal excessively high in fat, the undigested fat causes immediate, uncomfortable gastrointestinal side effects (steatorrhea, oily spotting). This acts as a strict, biological “training mechanism,” forcing the patient to adopt healthier, low-fat dietary habits to avoid discomfort, ensuring long-term behavioral change.
• The Cardioprotective & CNS-Safe Advantage: Unlike dangerous legacy diet pills (amphetamines) that cross the blood-brain barrier to suppress appetite—causing severe spikes in heart rate, hypertension, and anxiety—Orlistat has virtually zero systemic absorption. It provides profound weight loss and reverses Type 2 Diabetes risk markers entirely through mechanical gut action, making it exceptionally safe for patients with pre-existing cardiovascular disease.

Product Composition & Strength

We supply this product as a Precision-Engineered Micro-Pellet Capsule or Film-Coated Tablet, packed exclusively in highly secure, moisture-resistant Alu-Alu blister strips or heavy-gauge HDPE bottles to ensure the absolute chemical stability of the highly delicate API.

*Pack Sizes: Bottles of 84/120 or 10×10 Alu-Alu Blisters (Optimized specifically for strict 30-day chronic bariatric dispensing regimens, taken with every major meal).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Endocrinology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Cold-Process Extrusion & Low-Melting Point Engineering (CRITICAL COMPLIANCE): Orlistat is notoriously difficult to manufacture because it has a uniquely low melting point (approximately 43°C). Standard, high-friction pharmaceutical tableting or milling will literally melt the API into a useless, sticky paste, destroying the batch and ruining the machinery. Our facilities utilize specialized, jacket-cooled cold-process extrusion and spheronization technology to form uniform micro-pellets. This guarantees the API remains 100% structurally intact and thermally stable from our production lines to the patient’s digestive tract.

Therapeutic Indications (Human Use)

Indicated for the targeted, non-systemic management of severe metabolic dysfunction:

• Clinical Obesity: Weight loss and long-term weight maintenance in obese patients (BMI ≥ 30 kg/m²) in conjunction with a mildly hypocaloric diet.
• Overweight with Comorbidities: Weight management in overweight patients (BMI ≥ 28 kg/m²) presenting with associated risk factors such as Type 2 Diabetes, hypertension, or hyperlipidemia.

Dosage & Administration

Recommended Dosage (Strictly as per Endocrinologist Guidelines):

• Standard Adult Dosing: 120 mg taken orally three times a day (TID), with each main meal containing fat.
• Administration (THE MEALTIME FAT RULE): The dose should be taken during or up to 1 hour after the meal. If a meal is missed or contains absolutely no fat, the dose of Orlistat must be skipped. It only works by blocking fat; if there is no fat, the medication has nothing to do.
• The Vitamin Gap (CRITICAL CO-PRESCRIPTION): Because Orlistat blocks fat absorption, it severely impairs the body’s ability to absorb fat-soluble vitamins (Vitamins A, D, E, and K). Patients MUST take a daily multivitamin containing these specific vitamins at least 2 hours before or 2 hours after the Orlistat dose (typically at bedtime).

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Gastrointestinal Events (Steatorrhea): The most common side effects are entirely related to the unabsorbed fat: oily spotting, flatus with discharge, fecal urgency, and fatty/oily stool (steatorrhea). These effects increase drastically if the patient consumes a high-fat diet.
• Severe Hepatic Injury: Rare cases of severe liver injury with hepatocellular necrosis or acute hepatic failure have been reported. Patients must report any signs of jaundice, dark urine, or extreme fatigue immediately.
• Oxalate Nephropathy (Kidney Stones): Unabsorbed fat in the gut binds to calcium, leaving oxalates free to be heavily absorbed into the blood. This can lead to hyperoxaluria and severe oxalate kidney stones. Use with extreme caution in patients with a history of renal impairment.
• Cyclosporine & Levothyroxine Interactions: Orlistat drastically reduces the absorption of Cyclosporine (an immunosuppressant for transplant patients) and Levothyroxine (thyroid hormone). Doses must be separated by several hours, and blood levels must be heavily monitored.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Metabolic and Bariatric Formulations. Whether you are looking for a reliable Government Tender Supplier for obesity clinics in the Middle East or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.