Ondansetron Suspension

Description

Ondansetron Oral Suspension (2 mg / 5 ml)

Healthy Inc is a specialized global supplier and exporter of advanced gastroenterology, oncology, and pediatric therapeutics. We provide ultra-high-purity, kinetically stable Ondansetron Suspension, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Selective $5\text{-}HT_{3}$ Receptor Antagonist” is a critical strategic export to retail pharmacies, pediatric hospitals, and oncology clinics, serving as the globally preferred intervention for the prevention and treatment of nausea and vomiting induced by chemotherapy, radiotherapy, or surgery in children.

Product Overview

This formulation operates as a “Neurological and Peripheral Emesis Blocker.” It physically intercepts the chemical signals that tell the body to vomit, allowing for rapid oral rehydration.

• Mechanism 1 (Central CTZ Blockade): Ondansetron physically blocks Serotonin ($5\text{-}HT_{3}$) receptors in the Chemoreceptor Trigger Zone (CTZ) of the brain.

• Mechanism 2 (Peripheral Vagal Inhibition): It physically prevents serotonin from binding to receptors on the Vagus Nerve in the gastrointestinal tract, which is the primary pathway for travel-sickness and toxin-induced vomiting.

• Mechanism 3 (Non-Sedating Relief): Unlike older anti-emetics, it physically does not block dopamine or histamine receptors, ensuring relief without the risk of sedation or extrapyramidal side effects.

Product Composition & Strength

We supply this product as a Sterile, Clear to Pale Straw-Colored Liquid, optimized for stability and high pediatric compliance.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments acting on the digestive system / Others)

• CAS Number: 99614-02-5 (Ondansetron Hydrochloride)

• Dosage Form: Oral Liquid (Suspension/Solution)

• Packaging: 30 ml / 50 ml / 60 ml Amber PET or Glass Bottles with calibrated measuring cups. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Precision pH Balancing: Ondansetron is physically stable only within a narrow pH range. Our manufacturing process utilizes Precision Buffering to prevent the drug from degrading into inactive metabolites.

• Aseptic Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for immunocompromised oncology patients and infants.

• Non-Crystallizing Formula: We ensure a consistent physical viscosity that prevents “bottleneck crystallization,” common in generic ondansetron liquids.

Primary Indications

• Pediatrics: Management of severe vomiting associated with Acute Gastroenteritis (stomach flu).

• Oncology: Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) and Radiation-Induced Nausea.

• Surgery: Prevention and treatment of Post-Operative Nausea and Vomiting (PONV).

• General Practice: Relief of severe nausea when oral rehydration is physically impossible due to vomiting.

Dosage & Administration

• Children (under 4 years): Typically 2 mg (5 ml) three times daily.

• Children (4-12 years): Typically 4 mg (10 ml) three times daily.

• Administration: For maximum efficacy in chemotherapy, it should physically be administered 30 minutes before the start of treatment.

• Rehydration Note: It is physically best to wait 15-30 minutes after the dose before attempting to give the child water or ORS.

Safety Warning: For Oral Use Only. Heart Note: Physicians should physically monitor for QT prolongation in patients with pre-existing heart conditions. Constipation Note: A common physical side effect is mild constipation. Contraindication: Do not use in patients with known hypersensitivity to Ondansetron or other selective $5\text{-}HT_{3}$ antagonists (e.g., Granisetron).

Global Export & Contract Manufacturing

Healthy Inc is a premier Gastroenterology and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Ondansetron liquids. Whether you are a National Oncology Center in the CIS or a B2B Pharma Marketplace partner in Africa or SE Asia, we ensure secure, WHO-GMP compliant delivery.