Norfloxacin Metronidazole and Simethicone Oral Suspension

Description

Norfloxacin, Metronidazole & Simethicone Oral Suspension

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, pediatric medicine, and gastroenterology therapeutics. We provide ultra-high-purity, kinetically stabilized Triple-Action Anti-Diarrheal Suspension, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Antibacterial, Antiprotozoal & Anti-Flatulent” combination is a massive-volume strategic export to retail pharmacies, pediatric hospitals, and government health ministries, serving as the globally preferred intervention for infectious diarrhea, amoebic dysentery, and associated abdominal discomfort in children.

Product Overview

This formulation operates as a “Comprehensive Intestinal Recovery System.” It physically targets the biological cause of infection while mechanically relieving the physical symptoms of bloating and pain.

• Mechanism 1 (DNA Gyrase Inhibition – Norfloxacin): A fluoroquinolone that physically enters the bacterial cell and inhibits DNA Gyrase. This prevents the bacteria from replicating their DNA, leading to the rapid death of E. coli, Salmonella, and Shigella.

• Mechanism 2 (Anaerobic DNA Disruption – Metronidazole): Physically targets Entamoeba histolytica and Giardia lamblia. It creates toxic metabolites within the parasite that cause DNA strand breakage.

• Mechanism 3 (Surface Tension Reduction – Simethicone): A physically inert silicone polymer. It physically reduces the Surface Tension of gas bubbles in the gut, causing them to coalesce into larger bubbles that are easily expelled, providing immediate relief from “griping” pain.

Product Composition & Strength

We supply this product as a Sterile, Homogeneous, Micronized Suspension, optimized for stability and high pediatric compliance.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics / Antiprotozoals)

• CAS Numbers: 70458-96-7 (Norfloxacin) / 443-48-1 (Metronidazole)

• Dosage Form: Oral Liquid (Suspension)

• Packaging: 30ml / 60ml Amber PET Bottles with child-resistant caps. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Micronized Homogenization: Norfloxacin and Metronidazole Benzoate are physically insoluble. Our manufacturing process utilizes High-Shear Homogenization to ensure a perfectly smooth suspension, preventing “grittiness” and ensuring an exact dose in every spoon.

• Stable Emulsification: Simethicone is an oil-based polymer. We utilize Advanced Emulsification Technology to ensure it remains perfectly dispersed within the aqueous suspension without separation.

• Aseptic Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for children with compromised gut health.

Primary Indications

• Pediatrics: First-line treatment for Infectious Diarrhea and Amoebic Dysentery associated with gas and abdominal pain.

• Tropical Medicine: Management of Giardiasis and mixed intestinal infections.

• Gastrology: Relief of “Griping” pain and flatulence during gastrointestinal infections.

• Public Health: Rapid response for localized outbreaks of food-borne bacterial enteritis.

Dosage & Administration

• Children (2-5 years): Typically 5ml (one teaspoon) twice daily for 5 days.

• Children (6-12 years): Typically 10ml twice daily for 5 days.

• Administration: For maximum safety and to reduce potential gastric upset, it should physically be taken 1 hour before or 2 hours after food.

• Shake Well: The bottle must be physically shaken before each use to ensure all three active components are evenly distributed.

Safety Warning: For Oral Use Only. Alcohol Warning: Strictly avoid alcohol during and for 48 hours after treatment (Disulfiram-like reaction). Sun Note: Norfloxacin may physically cause Photosensitivity; keep the child out of direct sunlight during treatment. Contraindication: Do not use in patients with a history of tendon rupture or known hypersensitivity to Quinolones or Nitroimidazoles.

Global Export & Contract Manufacturing

Healthy Inc is a premier Anti-Infective and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume triple-action suspensions. Whether you are a National Health Tender in Africa or a B2B Pharma Marketplace partner in SE Asia, the CIS, or the Middle East, we ensure secure, WHO-GMP compliant delivery.