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Metformin hydrochloride & pioglitazone sr Tablets
Metformin tablets IP 500 mg
Each Filmcoated tablet contains :
Metformin HCl IP 500 mg
Metformin Tablets IP 1 gm
Each Film-coated tablet contains :
Metformin hydrochloride IP 1.0 gm
Metformin tablets BP
Each Filmcoated tablet contains :
Metformin HCL BP 500 mg
Metformin tablets BP
Each Filmcoated tablet contains :
Metformin Hydrochloride BP 850 mg
Trippleace Metformin- 500
Metformin tablets BP
Each Filmcoated tablet contains :
Metformin HCL BP 500 mg
METFORMIN HYDROCHLORIDE & GLIMEPIRIDE SR TABLETS
Each Sustained Release Tablet Contains :
Metmin Hydrochloride 500 mg
Glimepiride 1 mg
Excipients q.s
Usage: – Treat type 2 diabetes
Category: – Anti Diabetic drugs
Description
Metformin Hydrochloride & Pioglitazone Tablets (SR)
Healthy Inc is a specialized global supplier and exporter of advanced insulin-sensitizing fixed-dose combinations. We provide high-quality Metformin Hydrochloride (Sustained Release) & Pioglitazone Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Double-Sensitizer” formulation is a top export to diabetic care clinics, pharmacy chains, and chronic disease management boards in Africa, LATAM, and Southeast Asia, serving as a powerful option for patients with significant insulin resistance.
Product Overview
This formulation combines Metformin Hydrochloride (Sustained Release) with Pioglitazone Hydrochloride (a Thiazolidinedione).
The “Insulin Resistance” Specialist:
- Targeting the Root Cause: Unlike sulfonylureas that squeeze the pancreas, this combination targets Insulin Resistance, the core defect in Type 2 Diabetes.
- Pioglitazone Action: Activates PPAR-gamma receptors in fat and muscle cells, drastically increasing their sensitivity to insulin and reducing fatty acid levels.
- Metformin Action: Reduces excess glucose production in the liver and improves glucose uptake in muscles.
- Lipid Profile Benefit: Pioglitazone is known to improve HDL (Good Cholesterol) and reduce Triglycerides, offering added cardiovascular protection.
Product Composition & Strength
We supply this product as Sustained Release (SR) Matrix Tablets packed in Alu-Alu Blisters.
| Product Strength | Metformin HCl (SR) | Pioglitazone | Common Name |
|---|---|---|---|
| 500/15 mg | 500 mg | 15 mg | Pio-M 15 |
| 500/30 mg | 500 mg | 30 mg | Pio-M 30 |
| 1000/15 mg | 1000 mg | 15 mg | Pio-M Forte |
| 1000/30 mg | 1000 mg | 30 mg | Pio-M DS |
*Pack Sizes: Blister packs of 10s (Box of 10×10).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Sustained Release Film Coated Tablet (Oral) |
| Packaging | Alu-Alu Blister (Moisture & Light Sensitive) |
| Storage | Store below 25°C. Protect from moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate, CTD Dossier |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Polymorph Stability: Pioglitazone has different crystalline forms. Our manufacturing process ensures only the stable, therapeutically active polymorph is used.
- Moisture Control: Pioglitazone is sensitive to humidity. We use specialized low-humidity compression suites and Alu-Alu packaging to guarantee shelf-life stability.
Therapeutic Indications (Human Use)
Indicated for the management of Type 2 Diabetes Mellitus:
- High Insulin Resistance: Particularly beneficial for obese patients with significant insulin resistance (Metabolic Syndrome).
- Sulfonylurea Failure: An effective option for patients who cannot tolerate Sulfonylureas or are at high risk of hypoglycemia (this combination rarely causes low blood sugar).
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Timing: Usually taken once daily with the evening meal.
- Duration: It may take several weeks (4-8 weeks) to see the full effect of Pioglitazone on blood glucose levels.
- Swallowing: Swallow whole with water; do not chew or crush.
Safety Warnings:
- Fluid Retention: Pioglitazone can cause edema (swelling) and may exacerbate heart failure. Contraindicated in patients with Class III or IV Heart Failure.
- Bladder Cancer Risk: Long-term use has been linked to a slightly increased risk of bladder cancer. Avoid in patients with active bladder cancer or a history of it.
- Liver Monitoring: Liver function tests (LFTs) should be checked prior to initiation and periodically thereafter.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
