Description

Furazolidone Film-Coated Tablets (100 mg)

Healthy Inc is a specialized global supplier and exporter of advanced infectious disease, gastroenterology, and tropical medicine therapeutics. We provide ultra-high-purity, kinetically stabilized Furazolidone Film-Coated Tablets (100 mg), manufactured in WHO–GMP certified, strictly humidity- and light-controlled oral solid dosage facilities. This “Broad-Spectrum Nitrofuran Antiprotozoal & Antibacterial” is a massive-volume, highly critical export to tropical medicine centers, international NGO outbreak-response networks, dysentery clinics, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as a globally mandated, life-saving intervention for Cholera, Giardiasis, and severe bacterial enteritis.

Product Overview

This highly advanced formulation operates as a devastating, multi-target chemical weapon against gastrointestinal pathogens. It does not just stop bacteria from multiplying; it violently shreds their genetic code and destroys their metabolic engines, making it incredibly difficult for the pathogens to develop resistance.

The “DNA-Shredding Nitrofuran & Enteric Rescue” Specialist:

• Mechanism 1 (The Microbial Enzyme Destruction): Furazolidone is a synthetic nitrofuran derivative. Once ingested, microbial enzymes inside the bacteria or protozoa rapidly reduce the drug into highly reactive, toxic intermediates. These toxic metabolites violently bind to microbial ribosomes and DNA, physically shattering the pathogen’s ability to synthesize proteins or replicate. It provides rapid, bactericidal and antiprotozoal clearance directly within the gut lumen.
• Mechanism 2 (The Cholera & Dysentery Anchor): In catastrophic outbreak scenarios, waterborne pathogens cause massive, lethal fluid loss. Furazolidone is highly prized by NGOs because it rapidly sterilizes the gut against Vibrio cholerae, Salmonella, Shigella, and Giardia lamblia, drastically shortening the duration of severe diarrhea and halting community transmission.
• Mechanism 3 (The MAOI Paradox – CRITICAL CLINICAL DATA): Unique among antibiotics, Furazolidone possesses strong, dose-dependent Monoamine Oxidase Inhibitor (MAOI) properties. It prevents the human body from breaking down certain neurotransmitters and dietary amines. This dictates a highly specific, strict clinical protocol regarding patient diet and co-prescribed medications during the eradication therapy.

Product Composition & Strength

We supply this product as a Precision-Blended, Light-Shielded Tablet, packed exclusively in highly secure, opaque Alu-PVC or heavy-gauge Alu-Alu blister strips to ensure the absolute chemical survival of the intensely photolabile (light-sensitive) nitrofuran molecule.

*Pack Sizes: 10×10 Blisters (Optimized specifically for rapid NGO deployment and short-course 5-to-7 day dysentery eradication protocols).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Infectious Disease Distributors, and NGO Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Photostable Engineering & Rapid Dissolution (CRITICAL COMPLIANCE): The greatest risk in manufacturing Furazolidone is light exposure on the factory floor. Our specialized infectious disease suites utilize strict amber-lighting and immediate, heavy-gauge film-coating processes. Furthermore, because the drug must work directly in a heavily inflamed, violently flushing GI tract, we utilize elite superdisintegrants to ensure the tablet shatters and releases the API instantly upon contact with gastric fluids, guaranteeing maximum localized bacterial destruction.

Therapeutic Indications (Human Use)

Indicated for the targeted, highly specialized eradication of severe gastrointestinal infections:

• Bacterial Dysentery & Enteritis: Severe diarrhea caused by susceptible strains of Salmonella, Shigella, Campylobacter, and E. coli.
• Cholera: Adjuvant therapy alongside massive oral rehydration to rapidly clear Vibrio cholerae from the gut.
• Giardiasis: Highly effective eradication of Giardia lamblia protozoan infections.

Dosage & Administration

Recommended Dosage (Strictly as per WHO / Physician Guidelines):

• Adult Dosing: 100 mg taken orally four times a day (QID) for 5 to 7 days.
• Administration: Should be taken with food to massively reduce the severe gastric irritation, nausea, and vomiting frequently associated with nitrofuran antibiotics.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• The Hypertensive Crisis (MAOI Alert): FATAL WARNING: Because Furazolidone inhibits Monoamine Oxidase, patients MUST strictly avoid foods high in tyramine (aged cheeses, wine, smoked meats, yeast extracts) and over-the-counter cold medicines (containing ephedrine or pseudoephedrine) during therapy and for 4 days after. Combining these will trigger a catastrophic, potentially fatal spike in blood pressure.
• The Disulfiram-Like Reaction (Alcohol Ban): Patients must consume ABSOLUTELY NO ALCOHOL during treatment and for 4 days afterward. Mixing alcohol with Furazolidone causes a violent toxic reaction including severe flushing, chest pain, tachycardia, and vomiting.
• Hemolytic Anemia (G6PD Deficiency): The drug will cause severe red blood cell destruction (hemolysis) in patients, especially infants, with a genetic G6PD deficiency.
• Brown Urine: Furazolidone metabolites will completely change the color of the patient’s urine to an intense, dark brown. Patients must be explicitly warned of this harmless effect so they do not panic.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and NGO Health Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Antiprotozoals, Tropical Antibacterials, and Photostable FDCs. Whether you are looking for a reliable Government Tender Supplier for dysentery outbreak programs in Africa or a B2B Pharma Marketplace partner for Latin America, our highly regulated logistics network ensures timely, secure delivery of WHO-GMP certified products.