Fluconazole Oral Suspension

Description

Fluconazole Oral Suspension (50 mg / 5 ml)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, pediatric medicine, and dermatology-focused therapeutics. We provide ultra-high-purity, kinetically stabilized Fluconazole Oral Suspension, manufactured in WHO–GMP certified, high-precision liquid manufacturing facilities. This “Triazole Antifungal” is a critical strategic export to retail pharmacies, pediatric hospitals, and government health ministries, serving as the globally preferred intervention for the treatment of systemic and mucosal fungal infections in children and infants.

Product Overview

This formulation operates as a “Cell Membrane Architect Disruptor.” It physically prevents the fungus from building its protective outer wall, leading to the collapse and death of the pathogen.

• Mechanism 1 (Ergosterol Inhibition): Fluconazole physically inhibits the fungal cytochrome P450 enzyme, Lanosterol 14-alpha-demethylase.

• Mechanism 2 (Membrane Leakage): By blocking the conversion of lanosterol to ergosterol (the “cholesterol” of fungi), it physically creates holes in the fungal cell membrane.

• Mechanism 3 (Fungistatic Precision): This physical disruption stops the fungus from replicating, allowing the child’s immune system to clear the infection efficiently.

Product Composition & Strength

We supply this product as a Micronized Suspension, ensuring maximum bioavailability and shelf-life stability.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics – Antifungals)

• CAS Number: 86386-73-4 (Fluconazole)

• Dosage Form: Oral Liquid (Suspension)

• Packaging: 30ml / 60ml Amber PET or Glass Bottles with child-resistant caps and measuring cups. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Micronized Homogenization: Fluconazole is physically insoluble in water. Our manufacturing process utilizes High-Shear Homogenization to ensure the drug is perfectly micronized and suspended, preventing “settling” and ensuring an exact 50mg dose.

• Bioavailability Excellence: Our formulation ensures that the drug is physically absorbed almost completely (>$90\%$) from the GI tract, matching the efficacy of intravenous administration.

• Aseptic Filling: We utilize Automated Liquid Filling Lines with 100% microbial testing to ensure total safety for immunocompromised pediatric patients.

Primary Indications

• Pediatrics: First-line treatment for Oral Thrush (Oropharyngeal Candidiasis) in infants and children.

• Gastroenterology: Management of Esophageal Candidiasis.

• Dermatology: Treatment of systemic fungal skin infections and Tinea Capitis (Scalp Ringworm).

• Critical Care: Prophylaxis in immunocompromised children (e.g., those undergoing chemotherapy or with HIV).

Dosage & Administration

• Mucosal Infections: Typically 3 mg/kg to 6 mg/kg as a loading dose, followed by 3 mg/kg once daily.

• Systemic Infections: Typically 6 mg/kg to 12 mg/kg once daily, depending on severity.

• Administration: Can be taken physically with or without food.

• Shake Well: The bottle must be physically shaken before each use to ensure uniform drug distribution.

Safety Warning: For Oral Use Only. Liver Note: Long-term use requires physical monitoring of liver enzymes ($ALT/AST$). Interaction Note: Fluconazole is a potent CYP2C9 and CYP3A4 inhibitor; consult a physician regarding concurrent medications (e.g., Phenytoin or Warfarin). Contraindication: Do not use in patients with known hypersensitivity to Azole antifungals.

Global Export & Contract Manufacturing

Healthy Inc is a premier Anti-Infective and Pediatric Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume antifungal liquids. Whether you are a National Health Tender in Africa or a B2B Pharma Marketplace partner in the CIS, Middle East, or LATAM, we ensure secure, WHO-GMP compliant delivery.