Cabergoline Tablets

Description

Cabergoline Tablets (0.5 mg)

Healthy Inc is a specialized global supplier and exporter of advanced endocrinology, gynecology, and targeted neuro-hormonal therapeutics. We provide ultra-high-purity, kinetically optimized Cabergoline Tablets (0.5 mg), manufactured in WHO–GMP certified, high-precision specialized hormone containment facilities. This “Long-Acting Dopamine Agonist” is a premium strategic export to fertility centers, neuro-surgery departments, and government health ministries, serving as the globally mandated intervention for Hyperprolactinemia, Prolactin-secreting pituitary adenomas (Prolactinomas), and Parkinson’s Disease.

Product Overview

This formulation operates as a high-affinity “Off-Switch” for excessive hormone production. Cabergoline is a synthetic ergot derivative that mimics the body’s natural dopamine, providing a sustained inhibitory effect on the pituitary gland that lasts for several days.

• Mechanism 1 (D2-Receptor Specificity): Cabergoline acts as a potent, long-acting agonist at the D2-Dopamine Receptors located on the lactotroph cells of the anterior pituitary. This directly inhibits the synthesis and secretion of Prolactin.

   

• Mechanism 2 (Tumor Shrinkage): In patients with Prolactinomas, sustained D2 activation not only lowers hormone levels but can physically shrink the pituitary tumor, often avoiding the need for invasive neurosurgery.

   

• Mechanism 3 (The Kinetic Advantage): Unlike older drugs that require daily dosing, Cabergoline has an exceptionally long half-life (approximately 63–69 hours). This allows for Twice-Weekly Dosing, which significantly reduces the “Nausea/Vomiting” side effects common with other dopamine agonists.

   

Product Composition & Strength

We supply this product as a Precision-Compressed, Micro-Dose Tablet, packed in high-barrier Alu-Alu blister strips or specialized glass vials to ensure the stability of the active API.

Technical & Logistics Specifications

• HS Code: 3004.39.19 (Medicaments containing hormones – Other)

• CAS Number: 81409-90-7 (Cabergoline)

   

• Dosage Form: Uncoated Tablet (Scored for half-dosing)

• Packaging: Alu-Alu Blisters (MANDATORY). Cabergoline is extremely sensitive to moisture and light. Alu-Alu packaging ensures 24-month stability in Zone IVb tropical climates.

   

Manufacturing Authority & Compliance

• Hormone Containment (OEB 4): Cabergoline is a potent hormonal agent. Our facility utilizes Isolated Production Suites with dedicated AHUs (Air Handling Units) to ensure zero cross-contamination and 100% worker safety.

• Scored Tablet Precision: Our tablets are precision-scored to allow for 0.25 mg dosing (half-tablet) during the initial titration phase, a critical requirement for endocrinologists.

Primary Indications

• Gynecology: Treatment of idiopathic hyperprolactinemia and amenorrhea/infertility.

   

• Neuro-Endocrinology: Management of Prolactin-secreting pituitary microadenomas and macroadenomas.

   

• Lactation Management: Physiological suppression of puerperal lactation (when medically indicated).

Dosage & Administration

• Standard Dosing: Usually started at 0.25 mg to 0.5 mg twice weekly. The dose is titrated monthly based on serum prolactin levels.

   

• Administration: Best taken with food (preferably at bedtime) to minimize the risk of dizziness or nausea.

Safety Warning: Risk of Cardiac Valvulopathy (Heart Valve Damage) with long-term, high-dose use. Patients should undergo regular echocardiograms if on high doses. Use with caution in patients with severe hepatic impairment or pregnancy-induced hypertension.

Global Export & Contract Manufacturing

Healthy Inc is a premier Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-precision Hormonal Therapeutics. Whether you are a Fertility Clinic Network in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.