Description

Benfotiamine Tablets

Healthy Inc is a specialized global supplier and exporter of advanced endocrinology, neurology, and targeted metabolic therapeutics. We provide ultra-high-purity, kinetically optimized Benfotiamine Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Fat-Soluble Vitamin B1 Derivative” is a massive-volume strategic export to diabetic centers, neurology clinics, and government health ministries, serving as the globally mandated intervention for Diabetic Neuropathy, Retinopathy, and Nephropathy.

Product Overview

This formulation operates as a biochemical “Shield” against glucose-induced damage. Benfotiamine is an S-acyl derivative of Thiamine that bypasses the limited absorption pathways of standard B1, achieving significantly higher intracellular concentrations in the tissues most vulnerable to diabetes.

• Mechanism 1 (Transketolase Activation): Benfotiamine is a potent activator of the enzyme Transketolase. This enzyme reroutes harmful sugar breakdown products into safe alternative pathways, preventing them from damaging the cellular infrastructure.

• Mechanism 2 (Inhibition of AGEs): It physically blocks the formation of Advanced Glycation End-products (AGEs). AGEs are “sticky” proteins created by high blood sugar that cause the stiffening of blood vessels and the “dying back” of nerve fibers in the feet and hands.

• Mechanism 3 (The Lipid-Soluble Advantage): Because it is fat-soluble, Benfotiamine passes directly through cell membranes. It remains in the body longer and reaches the peripheral nerves much more effectively than water-soluble Thiamine, providing superior relief from “Burning Feet” and tingling sensations.

Technical & Logistics Specifications

• HS Code: 2936.22.00 (Vitamins – Vitamin B1 and its derivatives)

• CAS Number: 22457-89-2 (Benfotiamine)

• Dosage Form: Film-Coated Tablet

• Packaging: Alu-Alu or Alu-PVC Blisters. Protects the API from environmental humidity across Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Metabolic Precision: Our manufacturing process focuses on absolute chemical purity to ensure the S-acyl bond remains intact, guaranteeing the fat-soluble properties required for neuro-protection.

• Content Uniformity: We utilize Advanced Dry Blending to ensure that every tablet in a million-unit batch provides the exact clinical dose, critical for long-term diabetic therapy.

Primary Indications

• Endocrinology: Prevention and treatment of Diabetic Microvascular complications (Neuropathy, Retinopathy, Nephropathy).

• Neurology: Management of Alcohol-induced Polyneuropathy and Sciatica.

• Geriatrics: Cognitive support and prevention of glycation-related cellular aging.

Dosage & Administration

• Standard Adult Dosing: 150 mg to 600 mg per day, usually divided into two doses (e.g., 150 mg BID or 300 mg BID).

• Administration: Can be taken with or without food.

Safety Warning: Benfotiamine has an excellent safety profile with very low toxicity. Rarely, it may cause mild skin rashes or GI upset. It is not a replacement for insulin or oral hypoglycemic agents; it is a supportive therapy for the complications of high blood sugar.

Global Export & Contract Manufacturing

Healthy Inc is a premier Endocrine Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for specialized Metabolic Therapeutics. Whether you are a Diabetes Clinic Network in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery.