Description
Amantadine Hydrochloride Tablets (100 mg)
Healthy Inc is a specialized global supplier and exporter of advanced neurology, infectious disease, and targeted internal medicine therapeutics. We provide ultra-high-purity, kinetically optimized Amantadine Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Dopaminergic & Antiviral Agent” is a massive-volume strategic export to neurology clinics, geriatric hospitals, and government health ministries, serving as the globally mandated intervention for Parkinson’s Disease, Influenza A prophylaxis, and Drug-Induced Extrapyramidal Reactions.
Product Overview
This formulation operates as a “Neural Signal Enhancer.” Amantadine is unique because it works across two completely different biological systems: the dopamine pathways of the brain and the replication cycle of respiratory viruses.
Mechanism 1 (Dopamine Release & Reuptake): In the brain, Amantadine increases the release of Dopamine from presynaptic terminals and physically blocks its reuptake. This increases the amount of “active” dopamine available, helping to restore smooth motor control in Parkinson’s patients.
Mechanism 2 (NMDA Receptor Antagonism): It acts as a weak, non-competitive antagonist at NMDA receptors. By modulating glutamate overactivity, it helps reduce “dyskinesia” (involuntary movements) often caused by long-term Levodopa therapy.
Mechanism 3 (Antiviral M2-Channel Blockade): In respiratory infections, Amantadine blocks the M2 protein ion channel of the Influenza A virus. This prevents the virus from “uncoating” inside human cells, effectively stopping it from releasing its genetic material and replicating.
Product Composition & Strength
We supply this product as a Precision-Blended, Immediate-Release Tablet, packed in moisture-resistant Alu-Alu or Alu-PVC blister strips.
| Active Ingredient | Strength | Primary Clinical Function |
| Amantadine Hydrochloride USP/BP | 100 mg | The Standard Therapeutic Anchor: The globally validated dose for both Parkinsonian motor control and antiviral prophylaxis. |
| Excipients | Proprietary Matrix | Rapid-Release System: Engineered to ensure a consistent $T_{max}$ (peak concentration) of approx. 2 to 4 hours for reliable daily protection. |
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments acting on the CNS – Anti-Parkinson/Antivirals)
CAS Number: 665-66-7 (Amantadine Hydrochloride)
Dosage Form: Film-Coated or Uncoated Tablet
Packaging: Alu-Alu Blisters. Protects the API from environmental humidity; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.
Manufacturing Authority & Compliance
API Purity Excellence: Our manufacturing process focuses on absolute chemical stability, ensuring the Hydrochloride salt remains potent and free from degradation, providing the predictable clinical response required for neurological patients.
Bioequivalence Integrity: We provide comprehensive dissolution data to prove our generic matches the pharmacokinetic profile of the innovator brand (Symmetrel), ensuring a seamless transition for chronic patients.
Primary Indications
Neurology: Treatment of idiopathic Parkinson’s Disease and Postencephalitic Parkinsonism.
Psychiatry: Management of Extrapyramidal Reactions (shaking/stiffness) caused by antipsychotic medications.
Infectious Disease: Prevention and treatment of respiratory tract infections caused by Influenza A virus strains.
Dosage & Administration
Parkinson’s Disease: Standard dose is 100 mg once or twice daily.
Influenza A: 200 mg daily (as a single dose or 100 mg BID) for adults.
Administration: Can be taken with or without food. To avoid insomnia, the last dose should not be taken too late in the evening.
Safety Warning: CNS Side Effects. Monitor for hallucinations, confusion, or dizziness, especially in elderly patients. Monitor for Livedo Reticularis (a purplish skin mottling). Strictly contraindicated in patients with severe renal impairment or a history of untreated epilepsy/seizures.
Global Export & Contract Manufacturing
Healthy Inc is a premier Neurology and Anti-Infective Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for multi-functional CNS therapeutics. Whether you are a Geriatric Hospital Network in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.
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