Description

Streptomycin Sulfate for Injection

Healthy Inc is a specialized global supplier and exporter of essential anti-tubercular and critical infectious disease therapies. We provide high-purity Streptomycin for Injection (1 g), manufactured in WHO–GMP certified sterile powder facilities. This “First-Line Antimycobacterial” is a mandatory export to tuberculosis (TB) eradication centers, infectious disease clinics, and government health ministries in Africa, LATAM, and Southeast Asia, serving as a cornerstone intervention for severe, multi-drug-resistant TB and rare zoonotic infections.

Product Overview

This formulation contains Streptomycin Sulfate, a highly potent, bactericidal aminoglycoside antibiotic derived from the actinobacterium Streptomyces griseus.

The “Mycobacterium & Zoonotic” Specialist:

• Mechanism (Ribosomal Inhibition): Streptomycin passively diffuses through the outer cell membrane of susceptible bacteria and is actively transported across the inner membrane. It binds irreversibly to the 16S rRNA of the 30S ribosomal subunit. This binding interferes with the initiation complex of peptide formation and causes the misreading of mRNA, leading to the production of toxic, non-functional proteins and rapid bacterial cell death.
• Anti-Tubercular Backbone: It remains a critical first-line parenteral agent in the treatment of active Mycobacterium tuberculosis infections, particularly in severe, disseminated, or multi-drug-resistant (MDR-TB) cases where oral agents are insufficient or contraindicated.
• Rare & Severe Pathogens: Beyond TB, Streptomycin is the global gold standard treatment for life-threatening zoonotic diseases, including Plague (Yersinia pestis) and Tularemia (Francisella tularensis).

Product Composition & Strength

We supply this product as a Sterile Dry Powder for Injection (White to Off-White) in glass vials, requiring reconstitution with a provided sterile diluent.

*Pack Sizes: Single Vial or Tray of 50/100 Vials. (Often procured in massive bulk for government TB programs).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Aseptic Powder Filling: Because moisture drastically accelerates the degradation of Streptomycin Sulfate, our manufacturing lines utilize ultra-low humidity environmental controls during the aseptic powder filling process, ensuring the powder remains free-flowing and fully potent throughout its shelf life.
• Sterility Assurance: The active pharmaceutical ingredient undergoes rigorous sterile filtration and crystallization prior to filling under Grade A laminar airflow, ensuring an absolutely pyrogen-free product suitable for deep intramuscular administration.

Therapeutic Indications (Human Use)

Indicated for the treatment of severe infections caused by susceptible strains of microorganisms:

• Tuberculosis (TB): All forms of active Mycobacterium tuberculosis infection (always used in combination with other anti-TB drugs).
• Tularemia & Plague: The drug of choice for Francisella tularensis and Yersinia pestis.
• Bacterial Endocarditis: Caused by Enterococcus faecalis or Streptococcus viridans (used synergistically with Penicillin).
• Brucellosis: Severe Brucella infections (used in combination with Doxycycline or Tetracycline).

Dosage & Administration

Recommended Dosage (Strictly as per Infectious Disease Specialist):

• Route: Deep Intramuscular (IM) Injection ONLY. (Intravenous administration is generally not recommended due to toxicity risks, unless specifically directed by highly specialized ICU protocols).
• Tuberculosis (Adults): Typically 15 mg/kg (usually 1 g) daily via deep IM injection. Dosages must be reduced in patients over 60 years old or those weighing less than 50 kg.
• Tularemia / Plague: 1 g to 2 g daily in divided doses (every 12 hours) for 7 to 14 days.
• Administration Technique: Must be injected deeply into the upper outer quadrant of the gluteus maximus or mid-lateral thigh. Alternate injection sites daily to prevent severe local tissue irritation and sterile abscesses.

Safety Warnings (CRITICAL):

• BLACK BOX WARNING (Ototoxicity): Streptomycin accumulates in the endolymph of the inner ear. It can cause severe, irreversible damage to the 8th cranial nerve, resulting in permanent vestibular toxicity (vertigo, ataxia, loss of balance) and cochlear toxicity (deafness). Routine audiometric testing is highly recommended during prolonged therapy.
• BLACK BOX WARNING (Nephrotoxicity): Causes acute tubular necrosis. Renal function (BUN, serum creatinine) must be monitored closely. Dosages must be drastically reduced in patients with impaired renal function to prevent toxic serum accumulation.
• Neuromuscular Blockade: Can cause profound muscle weakness and respiratory paralysis, particularly when given to patients with myasthenia gravis or those receiving concurrent anesthesia/muscle relaxants.
• Pregnancy (Fetal Harm): Can cause congenital deafness in the fetus if administered to pregnant women.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Critical Care Antibiotics, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.