Description

Pantoprazole Sodium Delayed-Release Tablets (20 mg / 40 mg)

Healthy Inc is a premier global supplier of high-stability gastroprokinetic and acid-suppressant therapies. We provide premium Pantoprazole Sodium Tablets, manufactured in WHO–GMP certified specialized cephalosporin-free facilities. As a primary treatment for acid-peptic disorders, this product is a cornerstone export for gastroenterology clinics, surgical centers, and National Health Tenders in Southeast Asia, Africa, and the Middle East.

Product Overview

Pantoprazole is a substituted benzimidazole and a potent Proton Pump Inhibitor (PPI). It is specifically engineered to suppress the final stage of gastric acid production by forming a covalent bond with the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell.

The “Acid-Control” Specialist:

• Mechanism of Action: Pantoprazole is a prodrug that is activated in the acidic environment of the parietal cell canaliculi. It irreversibly inhibits the proton pump, providing long-lasting suppression of both basal and stimulated gastric acid secretion, regardless of the stimulus.
• Superior Stability: Pantoprazole is chemically more stable at neutral pH than other PPIs (like omeprazole). This leads to lower potential for drug-drug interactions, as it has a lower affinity for various cytochrome P450 isoenzymes.
• Targeted Healing: It is highly effective in promoting the healing of esophageal erosions and gastric ulcers, with a clinical profile that supports both acute treatment and long-term maintenance.

Technical & Manufacturing Specifications

Formulated with advanced enteric-coating to ensure bypass of gastric acid.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from specialized ISO 9001:2015 units.

• Advanced Enteric Coating (pH-Sensitive): Pantoprazole is acid-labile. Our tablets utilize a multi-layer coating technology with a pH-dependent polymer (Eudragit) that ensures the drug is released only in the duodenum (pH > 5.5), protecting the API from stomach acid.
• Hygroscopic Control: Pantoprazole Sodium is highly sensitive to moisture. Our manufacturing suites maintain a Relative Humidity (RH) below 40% during processing, ensuring the tablets remain physically and chemically stable throughout their 36-month shelf life.
• Bioequivalence Validation: Every batch is tested against the innovator (Protonix) using comparative dissolution profiles at both acidic and buffer stages to ensure identical clinical efficacy.

Therapeutic Indications & Clinical Symptoms

• GERD (Gastroesophageal Reflux Disease): Treatment of erosive esophagitis and associated symptoms like heartburn and acid regurgitation.
• Peptic Ulcer Disease: Healing of gastric and duodenal ulcers.
• Zollinger-Ellison Syndrome: Management of pathological hypersecretory conditions.
• NSAID-Induced Ulcer Prophylaxis: Prevention of gastric ulcers in patients requiring long-term NSAID therapy.

Dosage & Administration

• Standard Adult Dose: 40 mg once daily, preferably 30 to 60 minutes before breakfast for maximum efficacy.
• Instruction: Tablets must be swallowed whole; do not crush or chew, as this destroys the protective enteric coating.
• Safety Note: Generally well-tolerated; however, long-term use should be monitored for potential hypomagnesemia or vitamin B12 deficiency.

Global Export & Contract Manufacturing Services

Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to Gastroenterology Centers and Ministry of Health Tenders. We offer Third Party Manufacturing for Pantoprazole with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, UAE, and the Philippines, providing WHO-GMP quality at competitive B2B prices.

Commercial Inquiries

WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in