Description

Orciprenaline Sulphate Tablets (10 mg / 20 mg)

Healthy Inc is a specialized global supplier and exporter of advanced respiratory, pulmonology, and critical-care therapeutics. We provide ultra-high-purity, kinetically stabilized Orciprenaline Sulphate Uncoated / Film-Coated Tablets (10 mg / 20 mg), manufactured in WHO–GMP certified, high-throughput oral solid dosage facilities. This “Systemic Beta-Adrenergic Bronchodilator” is a massive-volume, highly lucrative export to pulmonology centers, rural health networks, retail pharmacy chains, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally trusted, highly accessible intervention for the continuous prevention and relief of bronchospasm in Asthma, Chronic Bronchitis, and COPD.

Product Overview

This highly reliable formulation contains Orciprenaline Sulphate, a robust, moderately selective sympathomimetic amine that travels systemically to rapidly reverse the dangerous constriction of the airways, allowing patients to breathe freely without relying on complex inhaler devices.

The “Systemic Airway Relaxant & High-Volume” Specialist:

• Mechanism 1 (The Beta-2 Bronchodilation): During an asthma attack or COPD exacerbation, the smooth muscles surrounding the bronchioles violently contract, choking off the air supply. Orciprenaline acts as a potent agonist at the Beta-2 adrenergic receptors located on these smooth muscles. Stimulation of these receptors activates the enzyme adenylate cyclase, which causes a massive spike in intracellular cyclic AMP (cAMP). This chemical cascade instantly relaxes the muscles, physically opening the airways and restoring normal oxygen flow.
• Mechanism 2 (Enhanced Mucociliary Clearance): Beyond just relaxing the muscles, Orciprenaline actively stimulates the microscopic hairs (cilia) lining the respiratory tract. This accelerates the clearing of thick, sticky mucus out of the lungs, which is a critical, life-saving feature for patients suffering from severe Chronic Bronchitis and emphysema.
• The “Accessible Oral Therapy” Advantage: In many developing regions, teaching elderly or pediatric patients how to properly use pressurized inhalers is clinically difficult and financially prohibitive. Oral Orciprenaline tablets provide a highly stable, easy-to-swallow, and highly affordable systemic therapy, guaranteeing patient compliance across vast, underserved populations.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Respiratory Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• High-Shear Uniformity Engineering: Systemic beta-agonists require extreme precision. If a tablet contains slightly too much active ingredient, it can cause violent heart palpitations; if too little, the patient may suffer a fatal asthma attack. Our facilities utilize advanced high-shear wet granulation and rigorous HPLC content uniformity testing to guarantee that every single tablet delivers the exact 10 mg or 20 mg dose, ensuring absolute clinical safety and predictable bronchodilation across massive production batches.

Therapeutic Indications (Human Use)

Indicated for the targeted, systemic management of reversible airway obstruction:

• Bronchial Asthma: Prophylactic maintenance and relief of acute bronchospasm associated with asthma.
• Chronic Obstructive Pulmonary Disease (COPD): Maintenance treatment of chronic bronchitis and emphysema characterized by reversible airway obstruction.
• Note: Not intended for the immediate reversal of severe, life-threatening acute bronchospasm (where fast-acting inhalers or IV therapies are mandated).

Dosage & Administration

Recommended Dosage (Strictly as per Pulmonologist Guidelines):

• Standard Adult Dosing: 20 mg taken orally three to four times daily.
• Pediatric Dosing (Children over 12): 10 mg to 20 mg taken three to four times daily. (Dosing for younger children must be strictly calculated by a physician based on body weight).
• Administration: Can be taken with or without food. Tablets must be swallowed whole with a glass of water.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• Cardiovascular Stimulation (Tachycardia): Because Orciprenaline is slightly less selective for Beta-2 receptors than newer drugs, it can heavily stimulate the Beta-1 receptors in the heart. This frequently causes rapid heart rate (tachycardia), palpitations, and increased blood pressure. It must be used with extreme caution in patients with coronary artery disease, arrhythmias, or severe hypertension.
• Severe Hypokalemia: Systemic beta-agonist therapy can drive potassium from the blood into the cells, resulting in severe hypokalemia (dangerously low blood potassium). This risk is massively amplified if co-administered with diuretics or systemic corticosteroids (which are frequently prescribed for COPD).
• Skeletal Muscle Tremor: A highly common side effect of systemic beta-agonists is a fine tremor of the skeletal muscles, particularly the hands, due to direct stimulation of beta-receptors in the muscle tissue.
• Paradoxical Bronchospasm: As with all bronchodilators, there is a rare risk of paradoxical bronchospasm immediately after dosing. If this occurs, the drug must be discontinued immediately.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and NGO Health Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Pulmonology and Respiratory Formulations. Whether you are looking for a reliable Government Tender Supplier for rural asthma clinics in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.