Description

Methylprednisolone Acetate Injection

Healthy Inc is a specialized global supplier and exporter of long-acting steroid suspensions. We provide high-purity Methylprednisolone Acetate Injection (40 mg / 80 mg), manufactured in WHO–GMP certified sterile injectable facilities. This “Extended Release” corticosteroid is a mandatory export to orthopedic clinics, rheumatology centers, and dermatology wards in Africa, LATAM, and Southeast Asia, serving as the standard for localized joint therapy and long-term systemic inflammation control.

Product Overview

This formulation contains Methylprednisolone Acetate, a water-insoluble ester of methylprednisolone that forms a crystalline suspension.

The “Depot” Specialist:

• Mechanism (Slow Release): Unlike the soluble Sodium Succinate salt (which acts immediately), the Acetate salt is a suspension. Upon injection into the muscle or joint, it forms a local “depot.” The active drug is slowly hydrolyzed and released over a period of 1 to 4 weeks, providing sustained anti-inflammatory coverage.
• Joint Preservation: When injected directly into a joint (intra-articular), it reduces synovial inflammation, pain, and swelling in conditions like Rheumatoid Arthritis and Osteoarthritis, often providing relief for weeks.
• Systemic Control: A single IM injection can control chronic allergic conditions (like seasonal rhinitis or asthma) for extended periods without the need for daily pills.

Product Composition & Strength

We supply this product as a Sterile Milky White Suspension in glass vials.

*Pack Sizes: 1 ml Vial, 2 ml Vial, or 5 ml Multi-dose Vial.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Micronization Technology: The duration of action depends on particle size. Our manufacturing utilizes advanced micronization to ensure a uniform crystal size distribution. This prevents needle blockage during injection and ensures a predictable release rate (no “dose dumping”).
• Sterile Suspension: Unlike solutions, suspensions cannot be filtered at the end. We use a fully aseptic manufacturing process to blend the sterile powder with the sterile vehicle, ensuring absolute sterility without compromising the suspension’s physical properties.

Therapeutic Indications (Human Use)

Indicated for local and systemic anti-inflammatory therapy:

• Intra-Articular (Joints): Rheumatoid Arthritis, Osteoarthritis, Bursitis, Tenosynovitis (Tennis Elbow).
• Intralesional (Skin): Keloids, Alopecia Areata, Discoid Lupus, Lichen Planus (injected directly into the lesion).
• Intramuscular (Systemic): Severe allergic rhinitis, drug hypersensitivity reactions, chronic asthma.
• Intrasynovial: Ganglion cysts.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intramuscular (IM), Intra-articular, or Intralesional ONLY.
• CRITICAL WARNING: NEVER ADMINISTER INTRAVENOUSLY (IV). This product is a suspension; IV injection can cause embolic stroke or cardiac arrest.
• Systemic (IM): 40 to 120 mg deep into the gluteal muscle (lasts 1–4 weeks).
• Large Joints (Knee/Hip): 20 to 80 mg per injection.
• Small Joints (Elbow/Wrist): 10 to 40 mg per injection.
• Keloids: 20 to 60 mg injected directly into the scar tissue.

Safety Warnings (CRITICAL):

• Tendon Rupture: Do not inject directly into the substance of a tendon (e.g., Achilles tendon); injection must be into the tendon sheath.
• Skin Atrophy: Injection into the subcutaneous fat can cause permanent dimpling or depigmentation of the skin. Use deep IM technique (Z-track).
• Septic Arthritis: Never inject into an already infected joint.
• Post-Injection Flare: Transient increase in pain may occur 24 hours after joint injection (Crystal Synovitis).

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Suspensions, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.