Description
Methylcobalamin (Active Vitamin B12) Tablets (500 mcg / 1500 mcg)
Healthy Inc is a specialized global supplier and exporter of advanced neurology, endocrinology, and metabolic-support therapeutics. We provide ultra-high-purity, kinetically stabilized Methylcobalamin Film-Coated / Sublingual Tablets (500 mcg / 1500 mcg), manufactured in WHO–GMP certified, highly specialized, light-controlled oral solid dosage facilities. This “Neurologically Active Vitamin B12 Coenzyme” is a massive-volume, highly lucrative export to neurology centers, diabetic care clinics, retail pharmacy networks, and government health ministries in LATAM, the CIS, Africa, and Southeast Asia, serving as the globally mandated, first-line intervention for Diabetic Peripheral Neuropathy, Megaloblastic Anemia, and severe neurological degeneration.
Product Overview
This highly advanced formulation bypasses the liver entirely, delivering the exact, active coenzyme form of Vitamin B12 directly across the blood-brain barrier and into the peripheral nervous system to actively rebuild damaged nerve fibers.
The “Myelin Sheath Rebuilder & Direct-Action” Specialist:
- Mechanism 1 (The Pre-Converted Advantage): Cheap, standard Cyanocobalamin must be processed by the liver to become active—a slow, inefficient process that fails in sick or elderly patients. Methylcobalamin is already in its neurologically active state. The moment it hits the bloodstream, it begins working, making it infinitely superior for rapid nerve rescue.
- Mechanism 2 (The Myelin Sheath Synthesis): In diabetic and alcoholic neuropathy, high blood sugar and toxins strip away the protective coating (myelin sheath) around the nerves, causing misfiring, agonizing burning pain, and numbness. Methylcobalamin violently accelerates transmethylation reactions. It supercharges the synthesis of lecithin and neuronal lipids, physically rebuilding the myelin sheath and restoring normal, pain-free nerve conduction.
- Mechanism 3 (Homocysteine Eradication): High levels of homocysteine in the blood are massively toxic to the cardiovascular system and brain. Methylcobalamin acts as a mandatory co-factor for the enzyme methionine synthase, actively breaking down toxic homocysteine into safe methionine, providing profound secondary protection against strokes and ischemic heart disease.
Product Composition & Strength
We supply this product as a Precision-Blended, Photostable Film-Coated Tablet, packed exclusively in highly secure, light-blocking Alu-Alu blister strips to ensure the absolute chemical survival of the delicate coenzyme.
| Active Ingredient | Strength | Primary Clinical Function |
|---|---|---|
| Methylcobalamin (Mecobalamin) Ph.Eur./USP | 500 mcg | Maintenance / Hematology Standard: Base therapeutic unit for the treatment of Megaloblastic/Pernicious anemia and general nutritional B12 deficiency. |
| Methylcobalamin (Mecobalamin) Ph.Eur./USP | 1500 mcg | Global Neurology Standard: Mega-dose adult therapy for the aggressive regeneration of peripheral nerves in Diabetic Neuropathy, Sciatica, and Trigeminal Neuralgia. |
| Excipients | Microcrystalline Cellulose / Croscarmellose Sodium / Magnesium Stearate / Titanium Dioxide / Premium Opaque Opadry Film | Diluent / Superdisintegrant / Lubricant / UV-Blocking Coating (Engineered specifically to form a heavy, opaque shield that completely locks out ultraviolet light, preventing the photolabile degradation of the active coenzyme) |
*Pack Sizes: 10×10 Alu-Alu Blisters (Optimized specifically for strict, 3-to-6 month chronic neurology dispensing regimens).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers, Neurology Distributors, and Hospital Procurement Boards.
| HS Code | 3004.50.90 (Medicaments containing vitamins or derivatives – Neurology) |
| CAS Number | 13422-55-4 (Methylcobalamin) |
| Dosage Form | Film-Coated Tablet / Sublingual Tablet |
| Packaging | Heavy-Gauge Alu-Alu Blisters (STRICTLY MANDATORY). Methylcobalamin is exceptionally sensitive to UV light and moisture. Standard clear PVC will result in massive API degradation. Strict Alu-Alu barrier packaging guarantees absolute chemical stability and full neuro-regenerative potency across Zone IVb tropical climates. |
| Storage | Store strictly below 25°C in a dry place. Protect heavily from Light. Keep inside the outer carton until use. |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Photolabile Shielding & Amber-Light Engineering (CRITICAL COMPLIANCE): Manufacturing Methylcobalamin separates premium facilities from cheap generic pressers. If exposed to standard white factory lights during compounding, the molecule degrades instantly. Our specialized neurology suites operate under strict, UV-filtered amber lighting. Combined with direct-compression dry-blending and an immediate titanium-dioxide opaque film coating, we guarantee that 100% of the active coenzyme survives the manufacturing process and reaches the patient’s nervous system intact.
Therapeutic Indications (Human Use)
Indicated for the targeted, rapid management of severe neurological damage and hematological disorders:
- Diabetic Peripheral Neuropathy: Aggressive repair of nerve damage, alleviating numbness, tingling, and burning pain in the extremities of diabetic patients.
- Megaloblastic & Pernicious Anemia: Treatment of severe B12-deficiency anemias where oral cyanocobalamin absorption is compromised.
- Sciatica & Trigeminal Neuralgia: Adjunctive therapy to accelerate nerve healing and reduce severe neuropathic pain.
- Alcoholic Neuropathy: Reversal of toxic nerve damage caused by chronic alcoholism.
- Hyperhomocysteinemia: Reduction of toxic homocysteine levels to protect cardiovascular health.
Dosage & Administration
Recommended Dosage (Strictly as per Physician Guidelines):
- Peripheral Neuropathy (Severe): 1500 mcg taken orally once daily, usually for a minimum of 3 to 6 months to allow for physical nerve regrowth.
- Anemia / Nutritional Deficiency: 500 mcg taken orally one to three times daily.
- Administration: Can be taken with or without food. Sublingual variants should be placed under the tongue and allowed to dissolve completely for direct bloodstream absorption.
Safety Warnings (CRITICAL Regulatory & Clinical Data):
- The Folate Masking Warning: Administering mega-doses of B12 can correct the red blood cell abnormalities of Folate (Vitamin B9) deficiency, while allowing the irreversible neurological damage of the folate deficiency to progress silently. Physicians must rule out or co-treat folate deficiency.
- Hypokalemia Risk (Severe Anemia): In cases of severe Megaloblastic Anemia, the sudden, massive production of new red blood cells triggered by Methylcobalamin can rapidly deplete the body’s potassium levels, leading to dangerous, potentially fatal hypokalemia. Potassium levels must be monitored during initial treatment.
- Leber’s Hereditary Optic Neuropathy: Cyanocobalamin is strictly contraindicated in this condition as it accelerates optic nerve atrophy; while Methylcobalamin is safer, any B12 therapy in these patients requires extreme specialist caution.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving international Pharma Traders, Wholesalers, and Neurology Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Neurological, Diabetic-Support, and Photolabile Formulations. Whether you are looking for a reliable Government Tender Supplier for diabetic clinics in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely, secure delivery of highly stable, WHO-GMP certified products.








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