Description
Mebendazole Tablet
Mebendazole Tablets USP / BP / IP (100 mg / 500 mg)
Broad-Spectrum Intestinal Anthelmintic & Deworming Agent
Healthy Life Pharma Private Limited, alongside our specialized global export and marketing division Healthy Inc, is a leading Indian manufacturer, CDMO services provider, and wholesale supplier of advanced tropical medicines, anti-parasitics, and essential public health therapeutics. We manufacture a comprehensive, internationally standardized portfolio of Mebendazole Tablets inside our WHO–GMP certified, high-capacity solid dosage manufacturing facilities.
Serving as a cornerstone molecule for global public health mass-deworming programs, this product represents a massive-volume strategic export to national health ministries, humanitarian relief agencies, non-governmental organizations (NGOs), state hospital purchasing pipelines, and digital B2B pharmaceutical marketplaces across Sub-Saharan Africa, the CIS region, LATAM, and South-East Asia.
Product Overview
This formulation operates as a “Parasite Microtubule Destabilizer.” It ensures rapid therapeutic clearance of intestinal worm infestations by selectively blocking the parasite’s internal cellular infrastructure, inducing a state of permanent metabolic starvation.
Mechanism 1 (Beta-Tubulin Agonist Binding): Mebendazole physically enters the worm’s structural matrix and chemically binds with high affinity to the parasite’s Beta-Tubulin subunit.
Mechanism 2 (Microtubule Polymerization Blockade): By binding to tubulin, it completely blocks the physical polymerization of microtubules within the parasite’s intestinal cells. This induces an immediate structural collapse of the worm’s cellular transport systems.
Mechanism 3 (Ultrastructural Degranulation & Starvation): The loss of cytoplasmic microtubules chemically blocks the parasite’s ability to absorb exogenous glucose. This triggers a rapid depletion of internal glycogen reserves, permanently starving the worm until it detaches from the host intestinal wall and is physically cleared through normal bowel movements.
Product Composition & Available Formats
We supply Mebendazole across the two primary compendial configurations required to execute either targeted individual eradication or high-velocity single-dose mass eradication protocols.
| Active Ingredient Monograph | Available Strengths | Formulation Matrix Delivery System | Primary Clinical Application |
| Mebendazole USP / BP / IP | 100 mg | Oral Solid Chewable / Dispersible Tablet | Targeted Multi-Dose Therapy: Standard baseline format for individual 3-day courses targeting specific multi-worm infestations (Pinworms, Roundworms, Hookworms). |
| Mebendazole USP / BP / IP | 500 mg | High-Mass Oral Solid Single-Dose Tablet | Mass Public Health Eradication: High-potency, single-dose format engineered for rapid deployment in mass community deworming campaigns. |
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments acting on parasitic diseases / Anthelmintics)
CAS Number: 31431-39-7 (Mebendazole)
Dosage Form Options: Standard Oral Compressed Tablets, Chewable Fruit-Flavored Tablets, or Water-Soluble Dispersible Tablets (calibrated for pediatric administration).
Packaging Configurations:
Retail Blisters: 6 Tablets per Blister Strip packed in high-barrier Alu-Alu (Cold-Form Foil) or PVC/PVDC strips (optimized for the standard 100 mg 3-day family course).
Institutional Tenders: Bulk packs of 100 / 500 / 1000 Tablets per induction-sealed HDPE Bottle to maximize shipping efficiency and lower baseline unit costs for public health ministries. Our tropicalized packaging matrices completely block environmental moisture transit, guaranteeing a full 36-month shelf life in hot, humid Zone IVb export environments.
Advanced Manufacturing Integrity & Quality Controls
Taste-Masking Chewable Matrix Engineering: Raw Mebendazole active powders are naturally unpalatable, which can cause pediatric non-compliance. Our processing blocks integrate a specialized Taste-Masking Matrix with Pharma-Grade Sucralose and Micronized Fruit Flavor Systems, physically transforming the chewable tablet into an easy-to-administer pediatric dosage.
High-Velocity Bulk Compression Precision: To satisfy multi-million unit public health tender deadlines, we operate automated, high-output rotary tableting lines equipped with Online Core Hardness Testers and Weight-Verification Matrix Systems, ensuring absolute weight and content uniformity across continuous multi-day production cycles.
Low Systemic Absorption Profile Calibration: Mebendazole is structurally designed to work locally inside the GI tract. Our formulation chemistry keeps systemic absorption low (less than 10%), ensuring that the active payload remains physically concentrated in the intestinal lumen to maximize parasite toxicity while preventing systemic side effects.
Primary Indications
Tropical Medicine: Single or mixed infestations caused by Enterobius vermicularis (Pinworm / Threadworm), Ascaris lumbricoides (Roundworm), Ancylostoma duodenale (Common Hookworm), Necator americanus (American Hookworm), and Trichuris trichiura (Whipworm).
Institutional Deworming: Mass eradication campaigns in hyper-endemic schools and community clusters.
Usage Instructions
Administration Matrix: For chewable formats, the tablet can be physically chewed, swallowed whole, or crushed and mixed thoroughly with food (such as applesauce or yogurt). For standard 100 mg courses, the protocol demands one tablet in the morning and one tablet in the evening for 3 consecutive days.
The Single-Dose 500mg Matrix: For mass deworming programs, a single 500 mg tablet is administered physically once, providing complete compliance without requiring a multi-day follow-up.
The Family Synchronization Directive: Because intestinal pinworms spread rapidly through shared environments and clothing, it is highly recommended to treat all family members or close household contacts simultaneously to physically eliminate cycles of reinfection.
Safety Warning: POTENT BROAD-SPECTRUM ANTIEPITHALAMIC ANTHELMINTIC. For Professional Medical Supervision and Mass Deworming Guidelines Only. Embryotoxic Hazard Warning: CONTRAINDICATED IN PREGNANCY. Mebendazole has shown embryotoxic properties in animal studies; do not administer to pregnant women, particularly during the first trimester. Age Limitation Note: Not recommended for pediatric use in infants aged less than 1 year due to rare reports of convulsive events in very young age groups. Contraindications: Absolute contraindications in pregnant patients, children under 1 year of age, or individuals presenting with documented hypersensitivity to benzimidazole derivatives.
Global CDMO Services & Wholesale Tender Supply
Healthy Life Pharma Private Limited and Healthy Inc provide complete, internationally validated Third-Party Contract Manufacturing (CDMO Services) and bulk private-label export supply for the entire Mebendazole portfolio. Because this molecule faces zero controlled-substance dual-licensing hurdles, our high-capacity lines can rapidly manufacture, release, and ship multi-container shipping loads. We handle all mandatory documentation (WHO-GMP Certificate, Certificates of Pharmaceutical Product – COPP, Certificates of Analysis – COA, Stability Testing Matrix Sheets, and Complete CTD Format Dossier sets) for seamless entry registration.
Commercial & Bulk Procurement Inquiries:
Corporate Head Office: Mumbai, Maharashtra, India
Primary Manufacturing Base: Boisar, Maharashtra, India
WhatsApp / Direct Call: +91 7710003340
Corporate Email: info@healthyinc.co.in
