Description

Ketorolac Tromethamine Injection

Healthy Inc is a specialized global supplier and exporter of high-potency non-narcotic analgesics. We provide high-purity Ketorolac Tromethamine Injection (30 mg / 1 ml), sourced from WHO–GMP certified sterile injectable facilities. This “Opioid Sparing” specialist is a top export to post-operative recovery units, trauma centers, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the most potent NSAID available—offering morphine-equivalent pain relief without the risk of respiratory depression or addiction.

Product Overview

This formulation contains Ketorolac Tromethamine, a pyrrolizine carboxylic acid derivative that acts as a potent non-steroidal anti-inflammatory drug (NSAID).

The “Morphine-Equivalent” Specialist:

• Mechanism (Potent COX Inhibition): Ketorolac is a non-selective inhibitor of Cyclooxygenase (COX-1 and COX-2). It completely shuts down the synthesis of prostaglandins, which sensitize pain receptors. Its analgesic potency is so high that 30 mg of IM Ketorolac provides pain relief comparable to 12 mg of Morphine or 100 mg of Meperidine.
• Opioid-Sparing Effect: Unlike opioids, it does not cause sedation, respiratory depression, or constipation. It is widely used in “Multimodal Analgesia” to reduce the need for opioid drugs by 25-50%, leading to faster patient recovery and discharge.
• Kidney Stone Protocol: It is highly effective for renal colic because it reduces renal blood flow and ureteral pressure, treating the cause of the pain (distention) rather than just masking it.

Product Composition & Strength

We supply this product as a Sterile Solution in Amber Glass Ampoules.

*Pack Sizes: Tray of 5 Ampoules, 10 Ampoules, or 50 Ampoules.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Ethanol Optimization: Ketorolac is slightly soluble in water but highly soluble in alcohol. We use a precise 10% ethanol concentration to ensure the drug stays in solution even during temperature fluctuations in transport, preventing crystallization which can cause injection site necrosis.
• Nitrogen Shielding: Ketorolac is sensitive to oxidative degradation (turning yellow). We utilize nitrogen purging during filling to maintain a clear, colorless solution for the full 24-36 month shelf life.

Therapeutic Indications (Human Use)

Indicated for the short-term (≤ 5 days) management of moderately severe acute pain:

• Post-Operative Pain: General, orthopedic, and gynecological surgeries.
• Renal Colic: Acute kidney stone pain.
• Musculoskeletal Trauma: Fractures and severe sprains.
• Sickle Cell Crisis: Acute pain episodes.
• Dental Pain: Severe pain after complex extractions.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intramuscular (IM) or Intravenous (IV) Bolus.
• Single Dose:
  • IM: 60 mg.
  • IV: 30 mg.
• Multiple Dose: 30 mg every 6 hours. Maximum daily dose 120 mg.
• Duration Limit (CRITICAL): DO NOT EXCEED 5 DAYS. Long-term use causes renal failure and gastric perforation.
• Elderly (>65 years): Reduce dose by 50% (Max 60 mg/day).

Safety Warnings (CRITICAL):

• Renal Toxicity: Ketorolac aggressively constricts renal arteries. Contraindicated in Renal Impairment or dehydration. Monitor Urine Output.
• Bleeding Risk: Ketorolac inhibits platelet function. Contraindicated pre-surgery (high bleeding risk) or in patients with active peptic ulcers/GI bleeding.
• Labor & Delivery: CONTRAINDICATED. It can close the fetal ductus arteriosus prematurely and inhibit uterine contractions.
• Aspirin Allergy: Do not use in patients with aspirin-sensitive asthma.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.