Description

Hydrocortisone Sodium Succinate Injection

Healthy Inc is a specialized global supplier and exporter of high-solubility corticosteroid therapies. We provide high-purity Hydrocortisone Sodium Succinate for Injection (100 mg / 250 mg / 500 mg), sourced from WHO–GMP certified sterile lyophilized facilities. This “Critical Response” steroid is a top export to emergency departments, intensive care units (ICU), and government health ministries in Africa, LATAM, and Southeast Asia, serving as the gold standard for rapid management of adrenal crisis, anaphylactic shock, and severe status asthmaticus.

Product Overview

This formulation contains Hydrocortisone Sodium Succinate, the highly water-soluble ester of hydrocortisone, specifically designed for rapid intravenous action.

The “Adrenal” Specialist:

• Mechanism (The Bio-Identical Power): Hydrocortisone is the synthetic version of Cortisol, the primary hormone produced by the human adrenal gland. In times of extreme stress (shock, trauma, or sepsis), the body may fail to produce enough cortisol. This injection provides immediate replacement, stabilizing blood pressure and suppressing the “cytokine storm.”
• Rapid Onset: Unlike oral steroids, the sodium succinate ester reaches peak tissue concentrations almost immediately after IV injection, making it the drug of choice for life-threatening emergencies.
• Shock Management: It increases the heart’s responsiveness to catecholamines (like Adrenaline), helping to pull patients out of refractory septic or anaphylactic shock.

Product Composition & Strength

We supply this product as a Sterile Lyophilized Powder for Injection in glass vials.

*Pack Sizes: Tray of 1 Vial + 1 Ampoule (WFI), 10 Vials, or 50 Vials.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Lyophilization Integrity: Hydrocortisone is sensitive to heat. Our low-temperature freeze-drying (Lyophilization) cycle ensures the powder remains a pure white, porous cake. This allows for near-instantaneous dissolution upon adding a solvent, critical for time-sensitive emergencies.
• pH Balance: Our formulation is precisely buffered to a pH of 7.0 – 8.0 upon reconstitution to prevent vein irritation and ensure stability when mixed with IV fluids like Saline or Dextrose.

Therapeutic Indications (Human Use)

Indicated for acute conditions requiring rapid and potent corticosteroid action:

• Adrenal Crisis: Acute adrenocortical insufficiency (Addisonian crisis).
• Anaphylactic Reactions: Severe allergic reactions (after Adrenaline).
• Status Asthmaticus: Severe, acute bronchial asthma flare-up.
• Septic Shock: Adjunct in patients unresponsive to vasopressors.
• Severe Skin Disorders: Stevens-Johnson Syndrome or Pemphigus.
• Encephalopathy: Acute cerebral edema (secondary to hydrocortisone-responsive conditions).

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intravenous (IV) Injection, IV Infusion, or Intramuscular (IM) Injection. (IV is preferred in emergencies).
• Adults: 100 mg to 500 mg initially. Can be repeated every 2 to 6 hours depending on clinical response.
• Status Asthmaticus: 100-200 mg every 6 hours.
• Administration:
  • Injection: Reconstitute with 2 ml (for 100mg) or 5 ml (for 250/500mg) of Sterile Water for Injection. Inject over 1-10 minutes.
  • Infusion: Dilute in 100-1000 ml of Saline or 5% Dextrose.

Safety Warnings (CRITICAL):

• Infection Risk: Steroids can mask symptoms of infection and suppress the immune response. Avoid in systemic fungal infections.
• Rapid Withdrawal: Sudden cessation of high-dose therapy can lead to fatal adrenal collapse. Taper the dose gradually after the emergency is resolved.
• Diabetes: Causes sudden spikes in blood glucose. Monitor diabetic patients closely.
• Electrolyte Imbalance: May cause sodium retention and potassium loss. Monitor blood pressure and electrolytes in ICU settings.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.