Cotrimoxazole Suspension

Description

Cotrimoxazole Oral Suspension (Sulfamethoxazole & Trimethoprim)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, tropical medicine, and pediatric therapeutics. We provide ultra-high-purity, kinetically balanced Cotrimoxazole Suspension, manufactured in WHO–GMP certified, high-precision facilities. This “Synergistic Sulfonamide Combination” is a massive-volume strategic export to retail pharmacies, public health organizations, and government health ministries, serving as a globally trusted intervention for respiratory, urinary, and gastrointestinal infections.

Product Overview

This formulation operates as a “Sequential Metabolic Strike.” It physically targets two different steps in the bacterial production of folic acid, ensuring the pathogen cannot produce DNA or replicate.

• Mechanism 1 (PABA Competition – Sulfamethoxazole): Physically competes with PABA in the bacterial cell, blocking the first step of Dihydrofolic Acid synthesis.

• Mechanism 2 (Reductase Inhibition – Trimethoprim): Physically binds to the enzyme dihydrofolate reductase, blocking the second step of Tetrahydrofolic Acid production.

• Mechanism 3 (Bactericidal Synergy): While each drug alone is often only bacteriostatic, the physical combination is Bactericidal (pathogen-killing), providing a $1+1=3$ clinical effect.

Product Composition & Strength

We supply this product in the standard 5:1 Ratio, optimized for maximum systemic efficacy and pediatric safety.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics – Sulfonamides)

• CAS Numbers: 723-46-6 (Sulfamethoxazole) / 738-70-5 (Trimethoprim)

• Dosage Form: Oral Liquid (Suspension)

• Packaging: 50ml / 60ml / 100ml Amber PET Bottles with measuring spoons. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Aseptic Liquid Filling: Our manufacturing process utilizes Automated Filling Lines with 100% microbial testing to ensure safety for pediatric populations.

• Uniformity of Content: We utilize High-Shear Homogenization to ensure the Sulfamethoxazole and Trimethoprim are perfectly micronized and suspended, preventing “settling” at the bottom of the bottle.

• Sugar-Free Excellence: We offer Sugar-Free and Alcohol-Free formulations to meet the highest international pediatric safety standards.

Primary Indications

• Pulmonology: Treatment and prophylaxis of Pneumocystis jirovecii pneumonia (PCP) and Acute Bronchitis.

• Urology: Effective management of uncomplicated Urinary Tract Infections (UTI).

• Gastroenterology: Treatment of Shigellosis and traveler’s diarrhea.

• ENT Medicine: Management of Acute Otitis Media in children.

Dosage & Administration

• Standard Regimen: Typically administered every 12 hours. Dosage is physically calculated based on the Trimethoprim component (usually 6-8 mg/kg/day).

• Administration: For maximum efficacy and to reduce gastric irritation, it should physically be taken with food or plenty of water.

• Shake Well: The bottle must be physically shaken before each use to ensure an exact dose.

Safety Warning: For Oral Use Only. Allergy Warning: Strictly Contraindicated in patients with a known history of Sulfa Allergy (risk of Stevens-Johnson Syndrome). Hydration Note: Patients must maintain high physical water intake to prevent the formation of crystals in the kidneys (Crystalluria). Pediatric Note: Not for use in infants under 2 months of age.

Global Export & Contract Manufacturing

Healthy Inc is a premier Anti-Infective and Public Health Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume sulfonamide liquids. Whether you are a National Health Tender in Africa or a B2B Pharma Marketplace partner in SE Asia or LATAM, we ensure secure, WHO-GMP compliant delivery.