Description
Ciprofloxacin & Tinidazole Tablets
Healthy Inc is a specialized global supplier and exporter of synergistic fixed-dose antibiotic combinations. We provide high-purity Ciprofloxacin & Tinidazole Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Dual-Spectrum” gastrointestinal specialist is a top export to hospitals, travel medicine clinics, and government dispensaries in Africa, LATAM, and Southeast Asia, recognized as the definitive empiric therapy for mixed aerobic-anaerobic infections and severe infectious diarrhea (Dysentery).
Product Overview
This formulation combines a potent fluoroquinolone (Ciprofloxacin) with a next-generation nitroimidazole (Tinidazole) to cover the full spectrum of gut pathogens.
The “Gut & Pelvic” Specialist:
- Synergistic Coverage (Aerobic + Anaerobic):
- Ciprofloxacin (The Aerobic Killer): Targets Gram-negative aerobic bacteria (like E. coli, Salmonella, Shigella) by inhibiting DNA gyrase.
- Tinidazole (The Anaerobic/Protozoal Killer): Targets anaerobic bacteria (like Bacteroides fragilis) and Protozoa (like Entamoeba histolytica, Giardia). It damages their DNA strands via reduction of its nitro group.
- Superior to Metronidazole: We utilize Tinidazole instead of the older Metronidazole because it has a longer half-life (allowing simpler dosing) and a significantly better side-effect profile (less nausea and metallic taste).
- Empiric Power: Ideal for “blind therapy” in mixed infections where the specific causative organism is unknown, such as post-operative abdominal infections or severe traveler’s diarrhea.
Product Composition & Strength
We supply this product as Film Coated Tablets (Oblong/Caplet shape). The coating is critical to mask the intense bitterness of both APIs.
| Active Ingredient 1 | Active Ingredient 2 | Strength Combination | Primary Role |
|---|---|---|---|
| Ciprofloxacin HCl | Tinidazole | 500 mg + 500 mg | Standard Adult Dose |
| Ciprofloxacin HCl | Tinidazole | 500 mg + 600 mg | High Potency / Amoebiasis |
| Excipients | Q.S. | Microcrystalline Cellulose / Opadry (Coating) | Disintegration & Taste Masking |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 20s, or Bulk HDPE Jars of 500s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.20.19 (Medicaments containing antibiotics) |
| Dosage Form | Film Coated Tablet (Oral) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister (Light Sensitive) |
| Storage | Store below 25°C. Protect from Light. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Taste Masking Engineering: Both Ciprofloxacin and Tinidazole are exceptionally bitter. An uncoated tablet would induce vomiting immediately. Our manufacturing process involves a robust film coating (usually orange or yellow) that remains intact during handling but dissolves rapidly in the stomach.
- Chemical Compatibility: We use specialized dry granulation techniques to ensure the two active ingredients remain stable and do not interact chemically within the tablet matrix before ingestion.
Therapeutic Indications (Human Use)
Indicated for the treatment of mixed aerobic-anaerobic infections:
- Gastrointestinal: Severe Diarrhea/Dysentery of mixed origin (Amoebic/Bacterial), Traveler’s Diarrhea, and Giardiasis.
- Dental Infections: Severe periodontitis or abscesses where both aerobic and anaerobic bacteria are present.
- Gynecological: Pelvic Inflammatory Disease (PID) and bacterial vaginosis (oral therapy).
- Surgical Prophylaxis: Prevention of infection before colorectal surgery.
- Diabetic Foot: Management of infected ulcers involving mixed flora.
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Adults: One tablet (500/600 or 500/500) taken twice daily.
- Duration: Typically 5 to 7 days depending on the severity of infection.
- Administration Rules (CRITICAL):
- Take After Food: To minimize gastric upset (nausea/metallic taste).
- Avoid Alcohol (Tinidazole Effect): Patients must strictly avoid alcohol during treatment and for 72 hours after the last dose. Tinidazole can cause a “Disulfiram-like reaction” (severe flushing, vomiting, tachycardia) if mixed with alcohol.
- Avoid Dairy/Calcium (Cipro Effect): Do not take with milk or antacids (calcium/magnesium) as they block Ciprofloxacin absorption.
Safety Warnings:
- Tendonitis: Ciprofloxacin carries a risk of tendon rupture. Use caution in elderly patients or athletes.
- Metallic Taste: A metallic or bitter taste in the mouth is a common but harmless side effect of Tinidazole.
- Neuropathy: Long-term use is not recommended due to risk of peripheral neuropathy.
- Pregnancy: Generally avoided during the first trimester due to potential teratogenicity.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
