Description
Chlordiazepoxide Hydrochloride Tablets
Healthy Inc is a specialized global supplier and exporter of psychotropic agents for addiction medicine. We provide high-purity Chlordiazepoxide Hydrochloride Tablets, sourced from WHO–GMP certified solid dosage facilities compliant with international controlled substance regulations. This “Gold Standard Detox” agent is a top export to alcohol rehabilitation centers, psychiatric hospitals, and government addiction control programs in Africa, LATAM, and Southeast Asia, serving as the primary pharmacotherapy for the safe management of acute Alcohol Withdrawal Syndrome (AWS).
[Image of Chlordiazepoxide mechanism enhancing GABA effects on chloride channels in the neuron]
Product Overview
This formulation contains Chlordiazepoxide Hydrochloride, a long-acting benzodiazepine that prevents the severe complications of sudden alcohol cessation.
The “Alcohol Detox” Specialist:
- Mechanism: Chlordiazepoxide binds to the benzodiazepine site on the GABA-A receptor. It potentiates the effect of GABA (the brain’s “brakes”), increasing the influx of chloride ions and hyperpolarizing the neuron. This counteracts the glutamate “storm” (hyperexcitability) that occurs when a chronic drinker stops consuming alcohol.
- Long Half-Life Advantage: Unlike shorter-acting agents (like Lorazepam), Chlordiazepoxide has a long half-life (up to 30 hours) and produces active metabolites (e.g., desmethyldiazepam). This provides a “self-tapering” effect, ensuring smooth plasma levels that prevent breakthrough seizures or Delirium Tremens (DTs) without requiring frequent dosing.
- Safety Profile: It is less potent mg-for-mg than Diazepam, offering a smoother onset of sedation which is considered safer for agitated patients.
Product Composition & Strength
We supply this product as Sugar Coated Tablets (often Green or Yellow). The robust coating is essential to mask the intensely bitter taste of the API and protect the light-sensitive drug.
| Active Ingredient | Strength (Standard) | Therapeutic Role | |
|---|---|---|---|
| Chlordiazepoxide HCl USP/BP | 10 mg | Mild Anxiety / Elderly / Taper End | |
| Chlordiazepoxide HCl USP/BP | 25 mg | Severe Anxiety / Alcohol Detox Loading | |
| Excipients | Q.S. | Sucrose / Talc / Calcium Carbonate | Sugar Coating (Light Barrier) |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 50s, or Bulk HDPE Jars (Strictly regulated).
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Psychotropic Substances – Check Local Regs) |
| Dosage Form | Tablet (Sugar Coated) |
| Packaging | PVC-Alu Blister or Alu-Alu Blister |
| Storage | Store below 25°C. Secure Storage (Controlled Drug). Protect from light. |
| Certificates | WHO-GMP, COPP, Psychotropic Export License |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Controlled Substance Compliance: Manufacturing is conducted in restricted-access zones. We possess the necessary Narcotics Commissioner Authorizations to export this molecule legally to compliant nations.
- Photostability: Chlordiazepoxide is highly sensitive to UV light. Our sugar-coating process provides a complete physical light barrier, ensuring the medication remains stable and potent in hospital storage conditions.
Therapeutic Indications (Human Use)
Indicated for the management of anxiety and withdrawal states:
- Alcohol Withdrawal: Prevention of tremors, agitation, hallucinations, and Delirium Tremens (DTs) during acute alcohol cessation.
- Anxiety Disorders: Short-term relief of severe anxiety and tension.
- Pre-Operative Apprehension: Used to calm patients before surgery.
Dosage & Administration
Recommended Dosage (Strictly as per Psychiatrist):
- Route: Oral.
- Alcohol Withdrawal (Standard Protocol):
- Day 1: 50 mg to 100 mg, followed by repeated doses as needed (up to 300 mg/day) to control agitation.
- Day 2 onwards: Gradually taper the dose by 20% daily over 5–7 days.
- Anxiety (Mild): 5 mg or 10 mg, 3 or 4 times daily.
- Anxiety (Severe): 20 mg or 25 mg, 3 or 4 times daily.
- Elderly: Limit to 5 mg BID (high risk of accumulation and falls).
Safety Warnings:
- Dependence: Long-term use (>4 weeks) leads to physical dependence. Schedule IV Controlled Substance. Do not stop abruptly after long-term use.
- Respiratory Depression: BLACK BOX WARNING: Concomitant use with Opioids or Alcohol may result in profound sedation, respiratory depression, coma, and death.
- Fall Risk: Causes drowsiness and ataxia (unsteady walk). Elderly patients are at high risk of hip fractures.
- Liver: Use with caution in patients with hepatic impairment.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
Commercial Inquiries
For hospital tenders, bulk export, or distributor pricing, please contact our export team.
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
