Chlordiazepoxide Hydrochloride Tablets

Healthy Inc is a specialized global supplier and exporter of the first-in-class benzodiazepine anxiolytics. We provide high-purity Chlordiazepoxide Hydrochloride Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Alcohol Detox Specialist” is a top export to rehabilitation centers, psychiatric hospitals, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the gold-standard therapy for the management of severe anxiety and acute alcohol withdrawal syndrome.

Product Overview

This formulation contains Chlordiazepoxide Hydrochloride, a long-acting benzodiazepine psychotherapeutic agent.

The “Smoother Withdrawal” Specialist:

• Mechanism (GABAergic): Chlordiazepoxide binds to stereospecific benzodiazepine receptors on the postsynaptic GABA-A neuron complex. This enhances the inhibitory effect of GABA (gamma-aminobutyric acid), increasing neuronal membrane permeability to chloride ions. The result is hyperpolarization and stabilization of the neuron, reducing anxiety and agitation.
• Metabolic Profile (Long-Acting): It acts as a prodrug with a long half-life. The liver metabolizes it into several active metabolites (Desmethylchlordiazepoxide, Demoxepam, Desmethyldiazepam, and Oxazepam). This “cascade” of active metabolites provides a smooth, self-tapering effect, making it ideal for alcohol detoxification as it prevents “rebound” seizures and anxiety better than short-acting agents.
• Detox Safety: Because of its slow onset and long duration, it has a lower abuse potential compared to faster-acting benzodiazepines like Alprazolam or Diazepam.

Product Composition & Strength

We supply this product as Sugar Coated or Film Coated Tablets (typically Green/Black or Green/White). The coating is essential to mask the intensely bitter taste of the HCl salt.

*Pack Sizes: Blister packs of 10s (Box of 10×10), 30s, 100s, or Bulk HDPE Jars of 1000s (Hospital Packs).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Photostability: Chlordiazepoxide is highly sensitive to UV light, which causes oxidation and discoloration. Our manufacturing process uses Amber or Opaque Blistering materials to ensure the tablets remain potent and stable in tropical climates.
• Dissolution Uniformity: We ensure precise particle size distribution of the API to guarantee consistent absorption, critical for managing acute agitation in withdrawal patients.

Therapeutic Indications (Human Use)

Indicated for the short-term management of:

• Acute Alcohol Withdrawal: Management of agitation, tremors, and impending delirium tremens (DTs).
• Severe Anxiety Disorders: Relief of anxiety and tension associated with psychoneurosis.
• Pre-Operative Anxiety: Relief of apprehension before surgery.

Dosage & Administration

Recommended Dosage (Strictly as per Psychiatrist):

• Route: Oral.
• Alcohol Withdrawal (Acute): 50 mg to 100 mg initially, repeated every 2-4 hours as needed until agitation is controlled (Max 300 mg/day). Reduce dosage gradually to zero.
• Severe Anxiety: 20 mg or 25 mg three or four times daily.
• Mild Anxiety / Elderly: 5 mg or 10 mg three or four times daily.
• Duration: Should be used for the shortest duration possible (usually < 2 weeks) to avoid dependence.

Safety Warnings:

• Concomitant Opioid Use (BLACK BOX WARNING): Combined use with opioids (Morphine, Codeine, etc.) may result in profound sedation, respiratory depression, coma, and death.
• Dependence: Risk of physical and psychological dependence increases with dose and duration. Do not stop abruptly; taper slowly to avoid withdrawal seizures.
• Fall Risk: Causes drowsiness and ataxia (loss of coordination), increasing fall risk in the elderly.
• Pregnancy: Contraindicated in the first trimester (teratogenic risk).

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.