Description

Cefuroxime & Sulbactam Injection

Healthy Inc is a specialized global supplier and exporter of synergistic second-generation cephalosporin combinations. We provide high-purity Cefuroxime & Sulbactam Injection (1.5g / 750mg), sourced from WHO–GMP certified sterile injectable facilities. This “Bio-Shield” formulation is a top export to pulmonology units, surgical wards, and government health ministries in Africa, LATAM, and Southeast Asia, serving as a superior alternative to plain Cefuroxime for treating polymicrobial infections and resistant community-acquired pathogens.

Product Overview

This formulation combines Cefuroxime, a second-generation cephalosporin with excellent respiratory tract penetration, and Sulbactam, a beta-lactamase inhibitor.

The “Spectrum-Extender” Specialist:

• Synergy (The “Resistance” Breaker): While Cefuroxime is effective against many organisms, bacteria like Staphylococcus aureus and Haemophilus influenzae increasingly produce beta-lactamases to destroy it. Sulbactam binds to these enzymes, “sacrificing” itself to protect the Cefuroxime, thereby restoring its original potency.
• Anaerobic Coverage: Plain Cefuroxime has limited activity against anaerobes. The addition of Sulbactam significantly expands the spectrum to cover anaerobic bacteria (like Bacteroides), making this combo ideal for intra-abdominal infections and gynecological surgeries where mixed aerobic/anaerobic flora are present.
• Surgical Prophylaxis Plus: It offers broader protection than Cefuroxime alone for “clean-contaminated” surgeries, reducing the risk of Surgical Site Infections (SSIs).

Product Composition & Strength

We supply this product as a Sterile Dry Powder for Injection in glass vials. The standard ratio is 2:1.

*Pack Sizes: Tray of 1 Vial, 10 Vials, or Box of 1/10 Vials with Water for Injection (WFI).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Hygroscopicity Management: Sulbactam Sodium is highly sensitive to moisture. We manufacture this combination in ultra-low humidity zones (< 20% RH) to prevent the powder from clumping or hardening, ensuring rapid reconstitution in the hospital setting.
• Compatibility Buffering: Cefuroxime and Sulbactam have different pH profiles. Our formulation is precisely buffered to ensure a neutral pH upon dissolution, minimizing injection site pain and preventing phlebitis during IV infusion.

Therapeutic Indications (Human Use)

Indicated for the treatment of polymicrobial and resistant infections:

• Respiratory Tract: Resistant Community-Acquired Pneumonia (CAP), Acute Exacerbation of Chronic Bronchitis (AECB) caused by beta-lactamase producing bacteria.
• Surgical Prophylaxis: Abdominal, Pelvic, and Orthopedic surgeries (Preventing Post-Op Infection).
• Gynecology: Pelvic Inflammatory Disease (PID) and post-partum infections.
• Skin & Soft Tissue: Diabetic foot infections (mild to moderate), abscesses.
• Bone & Joint: Septic arthritis where resistant Staph is suspected.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intravenous (IV) Infusion or Deep IM Injection.
• Adults: 1.5 g (1g + 500mg) every 8 hours.
• Severe Infections: 1.5 g every 6 hours.
• Surgical Prophylaxis: 1.5 g IV at induction of anesthesia. May repeat every 8 hours for 24 hours.
• Renal Impairment: Dose interval adjustment required if Creatinine Clearance < 30 ml/min.
• Reconstitution: Dissolve 1.5g vial in 10-20ml WFI. Shake vigorously.

Safety Warnings (CRITICAL):

• Penicillin Allergy: CONTRAINDICATED in patients with a history of anaphylaxis to beta-lactams. Cross-reactivity exists.
• Nephrotoxicity: Monitor renal function if used concurrently with aminoglycosides or loop diuretics.
• IM Injection: Can be painful. Use of 1% Lidocaine as diluent is recommended for IM administration.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.