Description

Cefpirome Sulfate Injection 1g

Healthy Inc is a specialized global supplier and exporter of advanced Fourth-Generation Cephalosporins. We provide high-purity Cefpirome Sulfate Injection (1g), sourced from WHO–GMP certified sterile injectable facilities. This “Empirical Powerhouse” is a top export to oncology wards, intensive care units (ICU), and government health ministries in Africa, LATAM, and Southeast Asia, serving as a primary empirical therapy for severe nosocomial infections and febrile neutropenia.

Product Overview

This formulation contains Cefpirome Sulfate, a fourth-generation cephalosporin known for its unique molecular structure and exceptional stability against beta-lactamases.

The “Zwitterionic” Specialist:

• Mechanism (The “Fast Mover”): Cefpirome is a Zwitterion (it has both positive and negative charges). This allows it to penetrate the outer cell membrane of Gram-negative bacteria significantly faster than third-generation cephalosporins (like Ceftazidime or Ceftriaxone).
• True Broad Spectrum: Unlike 3rd generation drugs which usually favor either Gram-negatives OR Gram-positives, Cefpirome covers BOTH effectively. It kills Pseudomonas aeruginosa (Gram-negative) while maintaining high potency against Staphylococcus aureus (Gram-positive).
• Enzyme Resistance: It has a low affinity for beta-lactamases (AmpC), meaning it is not easily destroyed by bacterial enzymes, making it effective against resistant strains found in hospital settings.

Product Composition & Strength

We supply this product as a Sterile Dry Powder for Injection in glass vials. It must be reconstituted with Water for Injection (WFI).

*Pack Sizes: Tray of 1 Vial, 10 Vials, or Box of 1/10 Vials with Water for Injection (WFI).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Sterile Crystallization: Cefpirome is sensitive to degradation. We utilize advanced sterile crystallization processes to ensure the powder remains free-flowing and chemically stable (white to pale yellow) throughout its shelf life.
• Solubility Optimization: The formulation includes precise buffering agents (Sodium Carbonate) to ensure rapid dissolution and a neutral pH upon reconstitution, reducing injection site pain.

Therapeutic Indications (Human Use)

Indicated for the treatment of severe infections in hospitalized patients:

• Febrile Neutropenia: Empirical therapy for cancer patients with low white blood cell counts and fever.
• Severe Pneumonia: Hospital-Acquired Pneumonia (HAP) and Ventilator-Associated Pneumonia (VAP).
• Complicated UTIs: Pyelonephritis caused by resistant organisms.
• Skin & Soft Tissue: Severe cellulitis, abscesses, and infected wounds.
• Bacteremia/Septicemia: Life-threatening blood infections.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intravenous (IV) Injection or Infusion.
• Adults: 1 g to 2 g every 12 hours.
• Severe Infections (Pseudomonas/Neutropenia): 2 g every 12 hours.
• Renal Impairment: Dose adjustment is mandatory if Creatinine Clearance < 50 ml/min.
• Reconstitution: Dissolve 1g vial in 10ml WFI. Shake well. Carbon dioxide may be released (vent the vial).

Safety Warnings (CRITICAL):

• Penicillin Allergy: CONTRAINDICATED in patients with a history of anaphylaxis to penicillins or cephalosporins.
• Nephrotoxicity: Monitor kidney function, especially when combined with aminoglycosides (like Amikacin/Gentamicin).
• Encephalopathy: High doses in renal failure patients can cause seizures or confusion.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.