Description
Artesunate & Amodiaquine Tablets (ACT Combo)
Healthy Inc is a premier global provider of Artemisinin-based Combination Therapies (ACTs). We provide premium Artesunate + Amodiaquine Tablets, manufactured in WHO–GMP certified specialized anti-infective units. This combination is a gold-standard treatment for uncomplicated Plasmodium falciparum malaria and is a vital export for National Malaria Control Programs (NMCP), NGO health missions, and Ministry of Health (MOH) tenders across Africa and Southeast Asia.
Product Overview
Artesunate + Amodiaquine (AS+AQ) is a fixed-dose combination (FDC) therapy designed to provide rapid clinical relief and complete parasitic clearance. By combining an ultra-rapid acting artemisinin derivative with a long-acting 4-aminoquinoline, this therapy ensures a high cure rate while protecting both molecules from the development of drug resistance.
The “High-Efficacy” Antimalarial Specialist:
- Biphasic Parasite Clearance: Artesunate acts rapidly against the blood-stage parasites (asexual forms), reducing the parasite biomass significantly within the first 24 hours. Amodiaquine, with its longer half-life, eliminates any remaining parasites, providing sustained therapeutic activity and preventing recrudescence.
- Transmission Control: Artesunate possesses potent gameticidal activity, which reduces the number of sexual-stage parasites available to infect mosquitoes, thereby breaking the cycle of transmission in endemic communities.
- WHO Recommended Protocol: Our AS+AQ tablets are formulated for a strict 3-day treatment regimen, optimized to achieve maximum patient compliance and clinical success in tropical environments.
Technical & Manufacturing Specifications
Available as Fixed-Dose Combination (FDC) or Co-blistered packs for pediatric and adult dosing.
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredients | Artesunate (AS) + Amodiaquine Hydrochloride (AQ) |
| Available Strengths | (25/67.5 mg), (50/135 mg), (100/270 mg) |
| Dosage Form | Film-Coated Tablets / Fixed-Dose Combination |
| HS Code | 3004.20.91 (Antimalarials) |
| Packaging | Tropical Grade Alu-Alu Blister (Crucial for moisture protection) |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified facilities.
- Moisture-Barrier Technology: Artesunate is highly susceptible to hydrolysis. We utilize specialized low-humidity manufacturing suites and high-performance Alu-Alu cold-form blisters to ensure a 36-month shelf life in hot and humid (Zone IVb) climates.
- Taste-Masking Coating: Amodiaquine is naturally very bitter. Our tablets are finished with a specialized film-coating to mask the taste, which is particularly critical for pediatric adherence.
- Strict Bioavailability Controls: We ensure that the dissolution profile of Amodiaquine meets international standards, guaranteeing that the long-acting component is absorbed effectively to prevent malaria relapse.
Therapeutic Indications & Clinical Symptoms
- Uncomplicated P. falciparum Malaria: Primary treatment for fever, chills, and sweats associated with laboratory-confirmed malaria.
- Artemisinin-Based Combination Therapy (ACT): Utilized in regions where parasites have developed resistance to chloroquine or sulfadoxine-pyrimethamine.
- Pediatric Malaria: Specifically dosed variants for infants and children to reduce mortality in high-risk zones.
Dosage & Administration
- Standard Course: Once-daily dosing for 3 consecutive days.
- Administration: Best taken with a meal (preferably containing some fat) to enhance the absorption of Amodiaquine.
- Safety Note: Should not be used for malaria prophylaxis. Contraindicated in patients with a history of hepatic dysfunction or leukopenia associated with amodiaquine use.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Antimalarial Exporter in Mumbai, catering to Global Health Tenders and National Health Ministries. We offer Third Party Manufacturing for Artesunate + Amodiaquine with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Nigeria, Ghana, Cameroon, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
