Description

Artemether Injection 80mg

Healthy Inc is a specialized global supplier and exporter of high-potency antimalarial injectables. We provide high-purity Artemether Injection (80mg / 1ml), sourced from WHO–GMP certified sterile injectable facilities. This “Adult Rescue Dose” is a top export to infectious disease hospitals, military field hospitals, and government health ministries in Africa (Sub-Saharan) and Southeast Asia, serving as the primary intramuscular therapy for severe and cerebral malaria in adults.

Product Overview

This formulation contains Artemether, a lipid-soluble derivative of Artemisinin, dissolved in a sterile oily vehicle for deep intramuscular administration.

The “Adult Critical Care” Specialist:

• Mechanism (The “Peroxide Bomb”): The antimalarial activity is derived from the endoperoxide bridge within the Artemether molecule. When it encounters the high iron (heme) content inside the malaria parasite, this bridge splits, releasing lethal free radicals that destroy the parasite’s cellular membranes and mitochondria.
• Cerebral Clearance: Being highly lipid-soluble, Artemether rapidly crosses the Blood-Brain Barrier (BBB). This is critical for treating Cerebral Malaria, where parasites clog the capillaries of the brain, causing coma and seizures.
• Rapid Biomass Reduction: It reduces the parasitic load significantly faster than Quinine, preventing the progression of the disease to fatal organ failure.

Product Composition & Strength

We supply this product as a Sterile Oily Solution in Amber Glass Ampoules. The 80mg strength is specifically formulated to minimize the injection volume for adult patients while delivering a potent therapeutic dose.

*Pack Sizes: Tray of 6 Ampoules or 10 Ampoules (Standard Adult Course).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Sterile Oil Technology: Injecting oil requires specialized manufacturing to ensure the vehicle is free from particulate matter and pyrogens. Our lines use double-filtration systems to guarantee a smooth, sterile injectable that minimizes injection site abscesses.
• Potency Stability: Artemether is sensitive to hydrolysis. We strictly control humidity during the filling process and use hermetically sealed Type I glass ampoules to ensure the drug remains potent in tropical climates.

Therapeutic Indications (Human Use)

Indicated for the treatment of severe and complicated malaria in adults:

• Severe Falciparum Malaria: Acute attacks of Multi-Drug Resistant (MDR) malaria.
• Cerebral Malaria: Essential for patients presenting with neurological symptoms (coma, confusion).
• Emergency Rescue: Used as a pre-referral treatment in rural areas before transport to a higher-level facility.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Deep Intramuscular (IM) Injection ONLY. (Gluteal muscle).
• WARNING: NEVER give Intravenously (IV). Use a large-bore needle (21G) due to viscosity.
• Loading Dose (Day 1): 160 mg (2 ampoules) given as a single dose or divided.
• Maintenance Dose (Day 2-5): 80 mg (1 ampoule) once daily.
• Total Course: 480 mg over 5 days. Switch to oral ACT (Artemisinin Combination Therapy) as soon as the patient can tolerate oral medication.

Safety Warnings (CRITICAL):

• Pulmonary Embolism: Accidental IV injection can cause fatal oil embolism in the lungs. Always aspirate before injecting to ensure the needle is not in a vein.
• Pregnancy: Contraindicated in the First Trimester unless life-saving. Safe for use in 2nd and 3rd trimesters.
• QT Prolongation: Monitor cardiac function if possible, though the risk is lower than with Quinine.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Sterile Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.