Description

Ampicillin Capsules

Healthy Inc is a specialized global supplier and exporter of essential broad-spectrum beta-lactam antimicrobials. We provide high-purity Ampicillin Capsules (250 mg / 500 mg), manufactured in WHO–GMP certified, completely dedicated penicillin oral solid dosage facilities. This “Extended-Spectrum Aminopenicillin” is a massive-volume, foundational export to primary care clinics, pediatric hospitals, NGOs, and government health ministries in Africa, LATAM, and Southeast Asia, serving as the gold-standard first-line intervention for respiratory tract, gastrointestinal, and susceptible urogenital infections.

Product Overview

This formulation contains Ampicillin (as Ampicillin Trihydrate), a highly potent, semi-synthetic aminopenicillin antibiotic.

The “Extended-Spectrum Beta-Lactam” Specialist:

• Mechanism (Cell Wall Synthesis Blockade): Like all penicillins, Ampicillin is bactericidal. It penetrates the bacterial cell envelope (utilizing porin channels in Gram-negative bacteria) and binds with high affinity to specific Penicillin-Binding Proteins (PBPs). It halts the final stage of peptidoglycan cross-linking, physically weakening the cell wall until osmotic pressure causes the bacteria to burst (lyse).
• The Aminopenicillin Advantage: While standard Penicillin G or V is highly effective against Gram-positive organisms, the addition of an amino group to the Ampicillin molecule allows it to penetrate the outer membrane of Gram-negative bacteria. This grants it potent activity against pathogens like Escherichia coli, Haemophilus influenzae, Salmonella, and Shigella.
• Beta-Lactamase Susceptibility: It is important to note that Ampicillin is destroyed by beta-lactamase enzymes. It is therefore highly effective against non-penicillinase-producing strains, making it an ideal, cost-effective first-line empirical therapy before highly resistant strains are suspected.

Product Composition & Strength

We supply this product as a Hard Gelatin Capsule, packed in moisture-resistant Alu-PVC or Alu-PVDC blister strips to preserve the trihydrate API structure.

*Pack Sizes: 10×10 Alu-PVC Blisters or Bulk Jars of 1000 Capsules for high-volume institutional and epidemic dispensing.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Primary Care Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• 100% Dedicated Penicillin Isolation: Regulatory guidelines strictly prohibit manufacturing penicillins in the same facilities as cephalosporins or general non-antibiotic drugs. Our Ampicillin is processed in a completely segregated manufacturing block featuring independent HVAC systems, airlocks, and dedicated operators to absolutely eliminate the risk of fatal cross-contamination.
• Gastric Dispersion Optimization: Formulated with premium disintegrants, ensuring the capsule shell ruptures rapidly in the stomach, achieving peak serum concentrations typically within 1.5 to 2 hours of ingestion.

Therapeutic Indications (Human Use)

Indicated for the treatment of community-acquired bacterial infections caused by susceptible strains:

• Respiratory Tract Infections (RTIs): Bronchitis, sinusitis, and otitis media caused by non-penicillinase-producing H. influenzae, Streptococcus pneumoniae, or Streptococcus pyogenes.
• Gastrointestinal Infections: Bacterial gastroenteritis caused by Salmonella species (including S. typhi) and Shigella.
• Genitourinary Tract Infections (UTIs): Uncomplicated cystitis caused by E. coli, Proteus mirabilis, or Enterococcus faecalis.
• Meningitis: (Often in combination with other agents) caused by Listeria monocytogenes or susceptible Neisseria meningitidis.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Administration (CRITICAL FOOD RULE): Unlike Amoxicillin, Ampicillin MUST be taken on an empty stomach (at least 30 minutes before or 2 hours after meals). Food significantly significantly impairs its absorption in the GI tract.
• Standard Adult Dose: 250 mg to 500 mg every 6 hours (four times daily).
• Severe Infections (Adults): Higher doses may be required depending on the severity and site of infection.

Safety Warnings (CRITICAL):

• BLACK BOX WARNING (Anaphylaxis): Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. It is strictly contraindicated in patients with a history of penicillin allergy. Cross-reactivity with cephalosporins is also possible.
• The “Mononucleosis Rash” (CRITICAL DIAGNOSTIC NOTE): A very high percentage of patients with infectious mononucleosis (Epstein-Barr virus) who receive Ampicillin develop a severe, generalized, non-allergic maculopapular rash. Ampicillin should not be administered to patients with suspected viral mononucleosis.
• Pseudomembranous Colitis: Can alter normal gut flora, leading to antibiotic-associated diarrhea or severe Clostridioides difficile-associated colitis (CDAC).

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Dedicated Penicillin Formulations, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.