Description

Acebrophylline Tablets (100 mg / 200 mg SR)

Healthy Inc is a specialized global supplier and exporter of advanced pulmonology, respiratory, and targeted internal medicine therapeutics. We provide ultra-high-purity, kinetically optimized Acebrophylline Tablets, manufactured in WHO–GMP certified, high-precision specialized oral solid dosage facilities. This “Mucoregulatory Bronchodilator” is a massive-volume strategic export to pulmonology hospitals, chest clinics, and government health ministries, serving as the globally preferred intervention for Chronic Obstructive Pulmonary Disease (COPD) and Bronchial Asthma.

Product Overview

This formulation operates as a “Dual-Path Respiratory Stabilizer.” It is a molecular salt of ambroxol and theophylline-7-acetic acid, designed to physically open the airways while thinning the mucus that blocks them.

• Mechanism 1 (Bronchodilation): Acebrophylline inhibits the enzyme Phosphodiesterase (PDE), which increases the levels of cAMP in the bronchial smooth muscles. This physically relaxes the airways, making it easier for the patient to breathe.

• Mechanism 2 (Mucoregulation & Surfactant): Unlike traditional bronchodilators, it stimulates the production of Surfactant. This reduces the “stickiness” of mucus, making it thinner and easier to cough up (expectorate).

• Mechanism 3 (Anti-Inflammatory Action): It inhibits the release of pro-inflammatory mediators like Leukotrienes and Histamine, reducing the underlying swelling in the lung tissue that triggers asthma attacks.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Other medicaments acting on the Respiratory System)

• CAS Number: 96989-76-3 (Acebrophylline)

• Dosage Form: Film-Coated Tablet / Sustained-Release Tablet

• Packaging: Alu-Alu Blisters. Protects the API from environmental humidity; our moisture-lock packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Impurity Profiling Excellence: Our manufacturing process focuses on absolute chemical purity to ensure the Ambroxol-Theophylline coupling remains stable, providing the superior cardiovascular safety profile that makes it better than standard Theophylline.

• Bioequivalence Integrity: We provide comprehensive dissolution profiles to prove our generic matches the pharmacokinetic curve of the innovator, ensuring reliable clinical outcomes for chronic respiratory patients.

Primary Indications

• Pulmonology: Treatment of Chronic Obstructive Pulmonary Disease (COPD).

• Respiratory Medicine: Management of Bronchial Asthma and Chronic Bronchitis.

• Acute Care: Relief of congestion and airway obstruction in productive cough conditions.

Dosage & Administration

• Standard Adult Dosing: 100 mg twice daily or 200 mg SR once daily.

• Administration: Best taken after food to ensure optimal gastric tolerability.

Safety Warning: Cardiac Awareness. Use with caution in patients with a history of cardiac arrhythmias or recent myocardial infarction. Renal/Hepatic Alert: Dose adjustment may be required for patients with severe liver or kidney impairment. Strictly contraindicated in patients with hypersensitivity to xanthine derivatives.

Global Export & Contract Manufacturing

Healthy Inc is a premier Respiratory Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Pulmonology therapeutics. Whether you are a National Health Tender Buyer in Africa or a B2B Pharma Marketplace partner in the CIS, we ensure secure, WHO-GMP compliant delivery.