Abacavir 600mg & Lamivudine 300mg Tablets.

Description

Abacavir & Lamivudine Tablets (600 mg / 300 mg)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, virology, and targeted immunology therapeutics. We provide ultra-high-purity, kinetically balanced Abacavir & Lamivudine FDC Tablets, manufactured in WHO–GMP certified, high-precision specialized antiviral facilities. This “Dual Nucleoside Reverse Transcriptase Inhibitor (NRTI) FDC” is a massive-volume strategic export to infectious disease hospitals, HIV/AIDS treatment centers, and government health ministries, serving as a globally mandated backbone component for Highly Active Antiretroviral Therapy (HAART).

Product Overview

This formulation operates as a “Genetic Chain Terminator.” It tricks the HIV virus into using “fake” building blocks when it tries to copy its genetic code, physically stopping the virus from multiplying.

• Mechanism 1 (Nucleoside Analogue Mimicry): Both Abacavir and Lamivudine are analogues of natural DNA building blocks. The HIV enzyme Reverse Transcriptase mistakenly picks up these drugs instead of real nucleosides.

• Mechanism 2 (DNA Chain Termination): Once incorporated into the growing viral DNA strand, these drugs physically prevent any further building blocks from being added. This “terminates” the chain, leaving the virus with an incomplete and useless genetic map.

• Mechanism 3 (Viral Load Suppression): By stopping replication at the earliest stage, the FDC effectively reduces the “Viral Load” in the blood to undetectable levels, allowing the patient’s immune system (CD4 cells) to recover.

Product Composition & Strength

We supply this product in the globally standardized “600/300” ratio, optimized for maximum efficacy with a convenient once-daily dosing schedule.

Technical & Logistics Specifications

• HS Code: 3004.90.99 (Medicaments containing other active substances – Antivirals)

• CAS Numbers: 136470-78-5 (Abacavir) / 134678-17-4 (Lamivudine)

• Dosage Form: Film-Coated Tablet

• Packaging: High-Density Polyethylene (HDPE) Bottles (30 or 60 tablets) or Alu-Alu Blisters. Our high-barrier packaging ensures 24-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Antiviral Purity Excellence: Our manufacturing process focuses on absolute chemical stability, ensuring the NRTI synergy remains potent and provides the predictable viral suppression required for chronic HIV management.

• WHO-Standard Segregation: We utilize Dedicated Non-Beta-Lactam Antiviral Blocks with advanced air filtration and primary containment to ensure zero cross-contamination, meeting the strictest international regulatory standards (WHO-GMP/Prequalification).

Primary Indications

• Infectious Disease: Treatment of HIV-1 infection in adults, adolescents, and children weighing at least 25 kg.

• Combination Therapy: Indicated for use as part of a complete antiretroviral regimen (usually combined with a Protease Inhibitor or Integrase Inhibitor).

Dosage & Administration

• Standard Adult Dosing: 1 tablet once daily.

• Administration: Can be taken with or without food.

• Important: Should not be used in patients with moderate or severe hepatic impairment.

Safety Warning: Hypersensitivity Reaction (HSR). Abacavir can cause fatal allergic reactions. MANDATORY: All patients should be screened for the HLA-B*5701 allele before starting treatment. If a reaction occurs (fever, rash, fatigue, GI symptoms), the drug must be stopped permanently. Lactic Acidosis: Monitor for signs of lactic acidosis and severe hepatomegaly with steatosis.

Global Export & Contract Manufacturing

Healthy Inc is a premier Antiviral Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume HIV therapeutics. Whether you are a Global Health Fund buyer in Africa or a B2B Pharma Marketplace partner in Southeast Asia, we ensure secure, WHO-GMP compliant delivery.