Fluconazole Infusion

Description

Fluconazole Intravenous (IV) Infusion (2 mg / ml)

Healthy Inc is a specialized global supplier and exporter of advanced anti-infectives, critical care, and hospital therapeutics. We provide ultra-high-purity, sterile Fluconazole Infusions, manufactured in WHO–GMP certified, high-precision large volume parenteral (LVP) facilities. This “Triazole Antifungal” is a massive-volume strategic export to tertiary care hospitals, emergency departments, and international B2B distributors, serving as the globally preferred intervention for severe systemic fungal infections where oral therapy is not feasible.

Product Overview

This formulation operates as a “Fungal Cell Wall Disruptor.” It physically enters the fungal cells to disable the enzymes required for maintaining their protective membrane.

• Mechanism 1 (Ergosterol Blockade): Fluconazole physically inhibits the fungal cytochrome P450 enzyme (14α-demethylase). This chemically stops the conversion of lanosterol to Ergosterol, the physical “building block” of the fungal membrane.

• Mechanism 2 (Cellular Leakage): Without ergosterol, the fungal membrane becomes physically weak and porous. This chemically leads to the leakage of essential nutrients, physically causing Cell Lysis (Death).

• Mechanism 3 (Blood-Brain Barrier Penetration): A key physical advantage is its ability to cross into the Cerebrospinal Fluid (CSF), making it chemically effective for treating fungal meningitis.

Product Composition & Strength

We supply this product as a Sterile, Non-Pyrogenic, Isotonic Solution for intravenous administration.

Technical & Logistics Specifications

• HS Code: 3004.20.19 (Medicaments containing other antibiotics / Antifungals)

• CAS Number: 86386-73-4 (Fluconazole)

• Dosage Form: Intravenous Infusion (IV)

• Packaging: 100 ml Self-Collapsible LDPE Bags (FFS Technology) or Glass Bottles. Our specialized packaging ensures 36-month stability in Zone IVb tropical climates.

Manufacturing Authority & Compliance

• Aseptic LVP Filling: Our manufacturing process utilizes Automated Large Volume Parenteral Lines with 100% terminal sterilization to ensure the product is physically free from all microbial and particulate matter.

• Non-Pyrogenic Testing: Every batch physically undergoes Bacterial Endotoxin Testing (BET) to ensure it is safe for direct entry into the human bloodstream.

• Solubility Precision: We utilize Advanced Solubilization Technology to ensure the Fluconazole remains physically stable in the saline base without crystallization during transit.

Primary Indications

• Critical Care: Treatment of Invasive Candidiasis and Systemic Yeast Infections.

• Neurology: Management of Cryptococcal Meningitis (especially in immunocompromised patients).

• Oncology: Prophylaxis against fungal infections in patients undergoing chemotherapy or bone marrow transplants.

• Gynaecology/Surgery: Severe cases of esophageal or mucosal candidiasis where oral intake is restricted.

Dosage & Administration

• Standard Adult Dose: Typically a Loading Dose of 400 mg on the first day, followed by 200 mg to 400 mg daily.

• Administration: Must be physically administered by Slow Intravenous Infusion at a rate not exceeding 200 mg per hour (100 ml/hr).

• Ready-to-Use: The 2mg/ml concentration is physically RTU and does not require further dilution.

• Sequential Therapy: Once the patient can swallow, they are physically transitioned to oral Fluconazole capsules.

Safety Warning: For Intravenous Infusion Only. Liver Note: Physicians must physically monitor Liver Function Tests (LFTs), as triazoles can chemically affect hepatic enzymes. Renal Note: Dosage must be physically adjusted in patients with impaired kidney function. Contraindication: Do not use in patients with known hypersensitivity to azole antifungals or concurrently with drugs that prolong the QT interval (e.g., Terfenadine).

Global Export & Contract Manufacturing

Healthy Inc is a premier Anti-Infective and Hospital Supply Pharmaceutical Exporter in India. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) for high-volume Fluconazole IV infusions. Whether you are a National Health Program in the CIS or a B2B Pharma Marketplace partner in Africa or SE Asia, we ensure secure, WHO-GMP compliant delivery.