Description

Telmisartan & Atorvastatin Tablets

Healthy Inc is a specialized global supplier and exporter of advanced cardiovascular, lipid-regulating, and metabolic therapeutics. We provide ultra-high-purity, kinetically segregated Telmisartan (40 mg) & Atorvastatin (10 mg) Film-Coated Tablets, manufactured in WHO–GMP certified, high-precision oral solid dosage facilities. This “Dual-Pathway Cardiovascular Synergy” is a massive-volume, high-value export to cardiology centers, metabolic clinics, primary care networks, and government health ministries in LATAM, the Middle East, Africa, and Southeast Asia, serving as the globally trusted, single-pill intervention for patients suffering from co-morbid essential hypertension and hypercholesterolemia.

Product Overview

This highly advanced Fixed-Dose Combination (FDC) masterfully synchronizes Telmisartan, the longest-acting Angiotensin II Receptor Blocker (ARB), with Atorvastatin, the globally dominant, high-potency statin for cholesterol reduction.

The “Comprehensive Metabolic & CV Defense” Specialist:

• Mechanism 1 (The Hemodynamic Shield – Telmisartan 40mg): Telmisartan aggressively binds to AT1 receptors on blood vessels, preventing Angiotensin II from causing vasoconstriction. This creates massive, sustained vasodilation, dropping systemic blood pressure. Uniquely, Telmisartan also acts as a partial agonist of PPAR-gamma, actively improving insulin sensitivity—a massive benefit for patients with Metabolic Syndrome.
• Mechanism 2 (The Plaque Stabilizer – Atorvastatin 10mg): While Telmisartan controls the pressure inside the vessels, Atorvastatin protects the vessel walls. It aggressively inhibits the HMG-CoA reductase enzyme in the liver, shutting down the body’s internal cholesterol production. This forces the liver to pull dangerous LDL (“bad”) cholesterol out of the bloodstream, shrinking arterial plaques and preventing heart attacks and strokes.
• The Synergy of Compliance: Hypertension and high cholesterol almost always present together, yet they are “silent” killers with no daily symptoms. Prescribing multiple separate pills leads to massive patient drop-off (non-compliance). Combining the foundational ARB and Statin into a single, once-daily pill guarantees that patients receive uninterrupted, 24-hour protection against both major drivers of cardiovascular mortality.

Product Composition & Strength

We supply this product as a Precision-Engineered Bilayer Film-Coated Tablet, packed exclusively in highly secure, moisture-resistant Alu-Alu blister strips to ensure the absolute stability of both the hygroscopic ARB and the sensitive Statin.

*Pack Sizes: 10×10 or 10×15 Alu-Alu Blisters (Optimized specifically for strict 30-day chronic cardiology adherence regimens).

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers, Cardiology Distributors, and Hospital Procurement Boards.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• Alkaline-Statin Segregation Engineering: Telmisartan requires highly alkaline stabilizers (like Meglumine and Sodium Hydroxide) to dissolve properly in the gut. However, this high alkalinity can chemically degrade Atorvastatin. Our facilities utilize advanced Bilayer Tablet Pressing Technology to physically separate the two active ingredients into distinct layers. This prevents cross-reactivity during shelf life and ensures both APIs deliver 100% of their therapeutic payload upon ingestion.

Therapeutic Indications (Human Use)

Indicated for the comprehensive management of cardiovascular and metabolic risk factors:

• Co-morbid Hypertension & Dyslipidemia: Treatment of patients who have both high blood pressure and elevated cholesterol levels (hypercholesterolemia or mixed dyslipidemia).
• Cardiovascular Risk Reduction: Prophylactic reduction of the risk of myocardial infarction (heart attack) and stroke in patients with multiple cardiovascular risk factors (e.g., Metabolic Syndrome, diabetes, obesity, smoking).

Dosage & Administration

Recommended Dosage (Strictly as per Cardiologist Guidelines):

• Standard Adult Dosing: One tablet taken orally once daily.
• Administration: Can be taken with or without food. Because endogenous cholesterol synthesis peaks at night, and Telmisartan has a full 24-hour half-life, this FDC is frequently prescribed to be taken in the evening for maximum lipid-lowering efficacy.

Safety Warnings (CRITICAL Regulatory & Clinical Data):

• BLACK BOX WARNING (Fetal Toxicity): The Telmisartan component can cause catastrophic injury and death to the developing fetus. Furthermore, Atorvastatin is contraindicated in pregnancy because cholesterol is essential for fetal development. Strictly contraindicated in pregnancy and lactation.
• Myopathy & Rhabdomyolysis: Atorvastatin can cause severe muscle tissue breakdown (rhabdomyolysis), leading to acute renal failure. Patients must be rigorously counseled to report any unexplained muscle pain, tenderness, or weakness immediately.
• Hepatotoxicity: Statins can cause elevations in liver transaminases. Liver function tests (AST/ALT) should be performed before initiating therapy and as clinically indicated thereafter. It is contraindicated in patients with active liver disease.
• Hyperkalemia: Because it blocks the RAAS system, Telmisartan causes the kidneys to retain potassium. Serum potassium levels must be monitored, especially in patients taking potassium supplements or potassium-sparing diuretics.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Retail Pharmacy Networks. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Advanced Cardiovascular FDCs, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for metabolic syndrome programs in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.