Description
Propantheline Tablets
Healthy Inc is a specialized global supplier and exporter of synthetic quaternary ammonium anticholinergics. We provide high-purity Propantheline Bromide Tablets, sourced from WHO–GMP certified solid dosage facilities. This “Gut Relaxant” is a top export to gastroenterology clinics, urology departments, and government health ministries in Africa, LATAM, and Southeast Asia, serving as an effective adjunct therapy for Peptic Ulcer Disease and Hyperhidrosis.
Product Overview
This formulation contains Propantheline Bromide, a synthetic antimuscarinic agent.
The “Secretions Dryer” Specialist:
- Mechanism (Anticholinergic): Propantheline works by competitively blocking the action of acetylcholine at postganglionic parasympathetic receptor sites (muscarinic receptors).
- GI Effect: By blocking these receptors in the stomach and intestines, it significantly reduces the volume and acidity of gastric secretions (acid) and inhibits gastrointestinal motility (spasms/cramps).
- Other Effects: It also blocks cholinergic activity in sweat glands (reducing excessive sweating) and the urinary bladder (reducing urgency and frequency).
- Quaternary Structure: Unlike tertiary amines (like Atropine), Propantheline is a quaternary ammonium compound. This means it is highly polar and does not cross the blood-brain barrier easily, resulting in fewer CNS side effects (confusion/drowsiness) compared to other antispasmodics.
Product Composition & Strength
We supply this product as Sugar Coated Tablets (typically Pink or White). The coating is essential to mask the extremely bitter taste of the drug.
| Active Ingredient | Strength (Standard) | Therapeutic Role | |
|---|---|---|---|
| Propantheline Bromide USP/BP | 15 mg | Standard Adult Dose | |
| Excipients | Q.S. | Lactose / Talc / Acacia | Filler / Binder |
*Pack Sizes: Blister packs of 10s (Box of 10×10), 100s, or Bulk HDPE Jars of 1000s.
Technical & Logistics Specifications
Critical data for Pharmaceutical Importers and Distributors.
| HS Code | 3004.90.99 (Other Medicaments) |
| Dosage Form | Tablet (Sugar Coated) |
| Packaging | PVC-Alu Blister or Alu-Alu (Moisture Sensitive) |
| Storage | Store below 25°C. Protect strictly from Moisture. |
| Certificates | WHO-GMP, COPP, Free Sale Certificate |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.
- Hygroscopicity Control: Propantheline Bromide is very hygroscopic (absorbs water from air). We manufacture in low-humidity suites and use moisture-barrier packaging to prevent the tablet from becoming sticky or degrading.
- Dissolution Profile: Despite being coated, our formulation ensures rapid disintegration in the stomach to provide quick relief from abdominal cramps.
Therapeutic Indications (Human Use)
Indicated for the treatment of conditions requiring reduced smooth muscle tone or secretions:
- Peptic Ulcer Disease: Adjunctive therapy to reduce gastric acid secretion and delay gastric emptying (allowing antacids to work longer).
- Irritable Bowel Syndrome (IBS): Relief of abdominal spasms, cramps, and hypermotility.
- Hyperhidrosis: Treatment of excessive sweating (off-label but common).
- Urinary Incontinence: Management of involuntary urination in adults (enuresis).
Dosage & Administration
Recommended Dosage (Strictly as per Physician):
- Route: Oral.
- Peptic Ulcer (Adults): 15 mg taken 30 minutes before each meal and 30 mg at bedtime (Total 75 mg/day).
- Hyperhidrosis / IBS: 15 mg three times daily. Adjust based on tolerance of side effects (dry mouth).
- Administration: Take 30 minutes before meals for optimal absorption and effect. Do not chew (bitter).
Safety Warnings:
- Glaucoma (CONTRAINDICATION): DO NOT USE in patients with narrow-angle glaucoma as it can increase intraocular pressure.
- Urinary Retention: Use with caution in elderly men with prostate enlargement (BPH), as it may cause complete urinary blockage.
- Heat Stroke: Reduces sweating. Avoid use in hot weather or during strenuous exercise to prevent overheating.
- Side Effects: Dry mouth, blurred vision, constipation, and tachycardia (fast heart rate) are common anticholinergic effects.
Global Export & Contract Manufacturing Services
Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for OSD (Oral Solid Dosage) forms, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.
