Description

Pheniramine Maleate Injection

Healthy Inc is a specialized global supplier and exporter of rapid-response anti-allergic therapies. We provide high-purity Pheniramine Maleate Injection (22.75 mg / ml), manufactured in WHO–GMP certified sterile facilities. This “Histamine Blocker” is a mandatory export to emergency departments, dermatology clinics, and government health ministries in Africa, LATAM, and Southeast Asia, serving as a first-line intervention for acute allergic reactions, angioedema, and severe pruritus.

Product Overview

This formulation contains Pheniramine Maleate, a potent first-generation alkylamine antihistamine with significant anticholinergic and mild sedative properties.

The “Receptor Antagonist” Specialist:

• Mechanism (Competitive Blockade): Pheniramine does not prevent the release of histamine but competes directly with free histamine for binding at H1-receptor sites on effector cells (smooth muscle, endothelial cells). This effectively blocks the vascular and cellular responses to histamine, preventing vasodilation, tissue swelling (edema), and extreme itching.
• Anticholinergic Action: It exerts a drying effect on the nasal and respiratory mucosa, making it highly effective in stopping excessive secretions during severe allergic rhinitis or respiratory allergies.
• Emergency Adjunct: While Epinephrine (Adrenaline) is the primary life-saving drug for anaphylactic shock, Pheniramine is the critical adjunctive therapy administered to completely halt the systemic histamine cascade.

Product Composition & Strength

We supply this product as a Sterile Clear Solution in glass ampoules.

*Pack Sizes: Tray of 10 Ampoules, 50 Ampoules, or 100 Ampoules.

Technical & Logistics Specifications

Critical data for Pharmaceutical Importers and Distributors.

Manufacturing Authority

Marketed and Distributed by Healthy Inc from WHO-GMP & ISO 9001:2015 certified units.

• pH Optimization: Formulated with a specific pH range to minimize pain and tissue irritation at the injection site, which is crucial for intramuscular delivery in distressed patients.
• Terminal Sterilization: The ampoules undergo validated terminal sterilization using moist heat to ensure a 100% sterile, pyrogen-free product suitable for direct intravenous bolus administration in emergencies.

Therapeutic Indications (Human Use)

Indicated for the rapid relief of allergic and hypersensitivity reactions:

• Acute Allergic Reactions: Severe urticaria (hives), angioedema, drug rashes, and insect stings/bites.
• Anaphylactic Shock: Used as an essential adjunct to Adrenaline.
• Respiratory Allergies: Acute allergic rhinitis and hay fever.
• Dermatological Conditions: Severe pruritus (itching) associated with eczema or contact dermatitis.
• Motion Sickness: Prevention and treatment of travel sickness and Meniere’s disease.

Dosage & Administration

Recommended Dosage (Strictly as per Physician):

• Route: Intramuscular (IM) or Slow Intravenous (IV).
• Adults: 1 to 2 ampoules (45.5 mg to 91 mg) IM or slow IV per day.
• Children: Strictly weight-based. Typically 0.5 to 1 mg/kg body weight daily in divided doses.
• IV Administration Protocol: If given IV, it must be injected very slowly (over at least 1 minute) to avoid transient hypotension and central nervous system stimulation.

Safety Warnings (CRITICAL):

• Severe Sedation: Causes profound drowsiness. Patients must be strictly warned not to drive, operate heavy machinery, or consume alcohol after administration.
• Anticholinergic Contraindications: Exacerbates conditions like Narrow-Angle Glaucoma, Prostatic Hypertrophy (causes acute urinary retention), and intestinal atony.
• Paradoxical Excitation: In pediatric patients, high doses may cause paradoxical CNS stimulation (restlessness, tremors, or convulsions) rather than sedation.

Global Export & Contract Manufacturing Services

Healthy Inc stands as a premier Pharmaceutical Exporter in India, dedicated to serving the needs of international Pharma Traders, Wholesalers, and Bulk Drug Distributors. As a verified Medicine Supplier in Mumbai, we offer flexible Third Party Manufacturing (Contract Manufacturing) services for Anti-Allergic Injectables, allowing brands to launch high-quality generic medicines under their own label. Whether you are looking for a reliable Hospital Tender Supplier for government procurement in Africa or a B2B Pharma Marketplace partner for Latin America, our logistics network ensures timely delivery. We actively support Pharmaceutical Drop Shipping models and bulk indenting, ensuring that every Generic Medicine Wholesaler receives WHO-GMP certified products at competitive rates.