Description
Ondansetron Tablets (4 mg / 8 mg)
Healthy Inc is a premier global supplier of high-precision supportive care and anti-emetic therapies. We provide premium Ondansetron Tablets, manufactured in WHO–GMP certified specialized solid dosage units. As a gold-standard treatment for the prevention of nausea and vomiting induced by cytotoxic chemotherapy and radiotherapy, this product is a vital export for oncology centers, surgical units, and Ministry of Health (MOH) tenders in Southeast Asia, Africa, and the Middle East.
Product Overview
Ondansetron is a potent, highly selective serotonin 5-HT3 receptor antagonist. It is specifically engineered to block the initiation of the vomiting reflex by inhibiting serotonin receptors located both on the vagal nerve terminals in the periphery and in the chemoreceptor trigger zone (CTZ) within the central nervous system.
The “Precision Anti-Emetic” Specialist:
- Mechanism of Action: Cytotoxic chemotherapy and radiotherapy cause the release of serotonin (5-HT) from the enterochromaffin cells of the small intestine. Ondansetron blocks the 5-HT3 receptors, preventing the sensory signal from reaching the brain’s vomiting center.
- Non-Sedative Relief: Unlike older anti-emetics, Ondansetron does not inhibit dopamine receptors, meaning it provides effective relief without causing extrapyramidal side effects or significant sedation.
- Post-Operative Recovery: It is the preferred agent for preventing and treating post-operative nausea and vomiting (PONV), facilitating faster recovery and discharge for surgical patients.
Technical & Manufacturing Specifications
Available as film-coated tablets and Orally Disintegrating Tablets (ODT).
| Technical Metric | Specification Standard |
|---|---|
| Active Ingredient | Ondansetron Hydrochloride BP / USP / IP |
| Dosage Form | Film-Coated Tablets / MDT (Mouth Dissolving) |
| Available Strengths | 4 mg, 8 mg |
| HS Code | 3004.90.99 (Medicaments) / 2933.99.00 |
| Packaging | Alu-Alu Blister (Crucial for light-sensitive ODT variants) |
Manufacturing Authority
Marketed and Distributed by Healthy Inc from ISO 9001:2015 certified units.
- ODT Technology: For patients suffering from severe nausea who cannot swallow, we offer Mouth Dissolving Tablets (MDT) that disintegrate on the tongue in seconds without the need for water.
- Bioavailability Precision: Our formulation ensures consistent pharmacokinetic profiles, essential for oncology patients who require predictable plasma levels to endure rigorous treatment cycles.
- Stability Validation: Validated for Climatic Zone IVb. Our tablets maintain chemical integrity and rapid disintegration times even in high-humidity tropical export markets.
Therapeutic Indications & Clinical Symptoms
- Chemotherapy-Induced Nausea & Vomiting (CINV): Prevention of acute and delayed emesis.
- Radiotherapy-Induced Nausea & Vomiting (RINV): Management of symptoms in patients undergoing total body or localized irradiation.
- Post-Operative Nausea & Vomiting (PONV): Prophylaxis and treatment in surgical settings.
- Severe Gastroenteritis: Off-label use in pediatric emergency care to reduce the need for IV rehydration.
Dosage & Administration
- CINV: Typically 8 mg taken 30 minutes before chemotherapy, followed by subsequent doses as prescribed.
- PONV: 16 mg administered one hour prior to the induction of anesthesia.
- Safety Note: May cause a mild increase in QT interval. Use with caution in patients with electrolyte imbalances or underlying cardiac conditions. Common side effects include headache and constipation.
Global Export & Contract Manufacturing Services
Healthy Inc is a verified Pharmaceutical Exporter in Mumbai, catering to Specialty Oncology Hospitals and Ministry of Health Tenders. We offer Third Party Manufacturing for Ondansetron with full CTD Dossier and COPP support. Our logistics network ensures secure transit to Vietnam, Nigeria, UAE, and the Philippines, providing WHO-GMP quality at competitive B2B prices.
Commercial Inquiries
WhatsApp/Call: +91 7710003340
Email: info@healthyinc.co.in
