Description
Olanzapine Tablet
Olanzapine Tablets (2.5 mg / 5 mg / 10 mg)
Healthy Life Pharma Private Limited, alongside our specialized global marketing and export division Healthy Inc, is a leading Indian manufacturer, CDMO partner, and bulk exporter of advanced neuro-psychiatry, mood stabilization, and mental health therapeutics. We manufacture ultra-high-purity, kinetically stable Olanzapine Tablets within our WHO–GMP certified, high-containment solid dosage manufacturing facilities. This advanced “Thienobenzodiazepine Atypical Antipsychotic” serves as a high-volume strategic export to psychiatric hospital networks, national health ministries, institutional procurement pipelines, and international B2B wholesale marketplaces across Europe, the CIS region, Africa, LATAM, and South-East Asia.
Product Overview
This formulation operates as a “Dual-System Monoaminergic Stabilizer.” It ensures patient safety by tuning down overactive neural transmission lines across both dopamine and serotonin networks, managing both the positive and negative symptoms of psychiatric disorders.
Mechanism 1 (Serotonin-Dopamine Antagonism): Olanzapine physically binds to and chemically blocks postsynaptic Serotonin $5\text{-HT}_{2\text{A}}$ receptors and Dopamine $D_{2}$ receptors in the brain. Its higher binding affinity for serotonin receptors chemically defines its “atypical” classification, minimizing severe motor side effects.
Mechanism 2 (Broad Receptor Affinity Network): It physically interacts as an antagonist across Muscarinic ($M_{1}\text{-}M_{5}$), Histaminergic ($H_{1}$), and Alpha-1 Adrenergic pathways, chemically contributing to its profound calming and sleep-stabilizing effects during acute manic crises.
Mechanism 3 (Mesolimbic Tuning): By chemically suppressing dopamine hyperactivity specifically within the mesolimbic pathway while sparing the nigrostriatal tract, it physically eliminates delusions and hallucinations without paralyzing the patient’s physical coordination.
Product Composition & Available Strengths
We supply Olanzapine in standard, exact strengths to facilitate initial titration phases and safe daily maintenance therapy.
| Active Ingredient | Available Strengths | Primary Clinical Target |
| Olanzapine IP / BP / USP | 2.5 mg | Introductory Titration: For low-dose introductory cycles, elderly adjustment, or sensitive patient profiles. |
| Olanzapine IP / BP / USP | 5 mg | Standard Maintenance: The baseline daily dosage for long-term schizophrenic and bipolar maintenance. |
| Olanzapine IP / BP / USP | 10 mg | Acute Crisis Control: High-potency therapeutic dosing to stabilize acute manic or severe psychotic episodes. |
Technical & Logistics Specifications
HS Code: 3004.90.99 (Medicaments acting on the central nervous system / Psychotropics)
CAS Number: 132539-06-1 (Olanzapine)
Dosage Formats: Oral Solid Film-Coated Tablets or Orally Disintegrating Tablets (ODT) designed to dissolve on the tongue in seconds without water.
Packaging: 10 or 14 Tablets per Blister packed in premium, high-barrier Alu-Alu (Cold-Form Foil) strips. Olanzapine is highly physically sensitive to ambient light and moisture; our quad-layer foil wrapping completely preserves chemical potency, ensuring a 36-month shelf life in hot, humid Zone IVb tropical environments.
Manufacturing Authority & Compliance
Psychotropic Containment Protocols: Olanzapine is a highly potent neuro-active substance. Our processing lines execute synthesis and tableting inside Dedicated, Negative-Pressure Isolation Suites running automated HEPA-filtered HVAC infrastructure, ensuring absolute containment and compliance with international B2B safety audits.
Advanced Orally Disintegrating Matrix (ODT): To prevent uncooperative psychiatric patients from pocketing or concealing tablets, we offer specialized ODT Matrix Compression Technology. These tablets physically melt upon contact with salivary fluids within 10–15 seconds, chemically forcing systemic ingestion.
Comparative Dissolution Profiling: Every production batch physically undergoes Automated Dissolution Profiling, chemically validating that our generic solid doses match the exact kinetic curves of the global innovator standard (Zyprexa).
Primary Indications
Psychiatry: Long-term management of acute and chronic Schizophrenia.
Mood Stabilization: Monotherapy or adjunctive management for Acute Manic or Mixed Episodes associated with Bipolar I Disorder.
Long-Term Prophylaxis: Prevention of symptom recurrence in patients presenting with a history of responsive bipolar management.
Usage Instructions
Standard Administration: Standard film-coated tablets must be swallowed physically whole with water, consistently either with or without food. ODT formats must be physically placed on the tongue to disintegrate instantly.
The Discontinuation Directive: It is physically vital never to halt this medication abruptly. Sudden cessation can chemically destabilize central receptor pathways, causing immediate psychotic relapse or withdrawal syndromes.
Metabolic Tracking Mandate: Because atypical antipsychotics can chemically alter insulin sensitivity and metabolic profiles, regular physical monitoring of patient body weight, fasting blood glucose, and lipid profiles is highly recommended.
Safety Warning: POTENT CRITICAL NEURO-PSYCHIATRIC AGENT. For Specialist Supervision Only. Metabolic Syndrome Risk: May chemically induce weight gain, hyperlipidemia, and hyperglycemia; monitor physical parameters closely. Drowsiness Caution: Physically induces significant central sedation; advise patients against driving or operating automated industrial machinery during initial adjustment phases. Contraindication: Do not use in patients presenting with a known history of narrow-angle glaucoma or hypersensitivity to the thienobenzodiazepine ring matrix.
Global Export & Contract Manufacturing (CDMO Services)
Healthy Life Pharma Private Limited provides complete, fully validated Third-Party Contract Manufacturing (CDMO) and bulk private-label export pipelines for generic Olanzapine Tablets and ODTs. Whether you are executing a procurement contract for a National Mental Health Tender across the CIS region, supplying a hospital pharmacy network in Africa, or managing an inventory listing on an international digital B2B Pharmaceutical Marketplace in Southeast Asia or LATAM, we deliver all required documentation (WHO-GMP Certificate, COPP, COA, Stability Testing Matrix Sheets, and Complete CTD Format Dossier sets) for seamless customs clearance.
Commercial & Bulk Procurement Inquiries:
Corporate Head Office: Mumbai, Maharashtra, India
Primary Manufacturing Base: Boisar, Maharashtra, India
WhatsApp / Direct Call: +91 7710003340
Corporate Email: info@healthyinc.co.in
